A cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective...
"Simply put, a patient in remission may still harbor malignant cells (ones that were resistant to chemotherapy or radiation), that – though we are getting diagnostically better with new testing techniques discovering CTCs, “circulating tumor cells” – not even the best diagnostic technologies can detect these with certainty."
New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led to the identification of...
Scientists have developed a statistical image analysis method which can assist in the grading of breast cancer by automatically segmenting tumour regions and detecting dividing cells in tissue samples.
"African-American women, for instance, are much more likely to develop triple-negative breast cancer, which tends to be more aggressive and does not respond to any of the targeted therapies researchers have developed."
“Early detection is not the answer. Finding and treating all stage 0 breast cancer will not prevent all breast cancer deaths. Something I have an issuewith,” wrote Dr. Attai, “is that early detection is often equated with survival."
"According to a published study in the New England Journal of Medicine, women with dense tissue in 75% or more of the breast have a risk of breast cancer four to six times as great as the risk among women with little or no dense tissue. Since dense breast tissue decreases mammography's effectiveness in detection, the somo(TM) ABUS has proven to be a tremendous advancement in the visualization of cancer-hiding tissue in dense breasts."
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