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Generex Announces Antigen Express AE37 Breast Cancer Vaccine Abstract Presentations at ASCO 2014 Meeting

Generex Announces Antigen Express AE37 Breast Cancer Vaccine Abstract Presentations at ASCO 2014 Meeting | Breast Cancer News | Scoop.it

"WORCESTER, Mass. and TORONTO, April 23, 2014 /PRNewswire/ -- Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that two abstracts in respect of results of the on-going Phase II study of a novel cancer vaccine designed to prevent relapse in patients who have had breast cancer will be presented at this year's American Society of Clinical Oncology (ASCO) Annual Meeting to be held in Chicago from May 30 to June 3, 2014.  The ASCO Annual Meeting is the premier annual oncology symposium, bringing together more than 25,000 oncology professionals from a broad range of specialties.

The abstracts, entitled "Primary analysis of prospective, randomized, single-blinded phase II trial of AE37 vaccine vs GM-CSF along administered in the adjuvant setting to high risk breast cancer patients" and "Immunogenic Comparison of Recurrent and Non-Recurrent Breast Cancer Patients Undergoing AE37 Peptide Vaccine Therapy", will be poster presentations on Monday, June 2 from 8:00 am CDT to 11:45 am CDT.

The AE37 cancer vaccine is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com).  The vaccine is designed to stimulate an immune response against the patient's cancer cells, preventing relapse in patients who have been treated for early stage breast cancer.

The recent analysis is based on data from nearly 300 patients, making this the largest controlled and randomized trial of a breast cancer vaccine trial conducted to date.  The data corroborate qualitatively the data reported after an interim analysis conducted two years ago.  Specifically, the more prevalent population of breast cancer patients ineligible to receive the drug Herceptin, and particularly those in high-risk groups (e.g., triple negative breast cancer), appear to benefit most from AE37.  Both of these patient populations represent areas of significant unmet need."



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For more information about the AE37 Breast Cancer Vaccine go to:  http://www.antigenexpress.com/AntigenExpress_FactSheet_v6%20110525.pdfhttp://www.cancernetwork.com/breast-cancer/asco-ae37-peptide-vaccine-may-help-prevent-breast-cancer-recurrence, and http://www.antigenexpress.com/AntigenExpress_FactSheet_v6%20110525.pdf

Looking forward to the new data to be presented at the ASCO Annual Meeting May 30th to June 3, 2014.


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The most common cause of cancer? Simple bad luck

The most common cause of cancer? Simple bad luck | Breast Cancer News | Scoop.it
Despite the belief cancer is usually inherited or triggered by lifestyles, two thirds of cases can be put down to DNA errors, experts from Johns Hopkins Kimmel Cancer Center claim.
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While this article lacks scientific sources, the headline and information are true! Many people with healthy lifestyles get cancer.

It would be nice to have more investigation and studies presented to the public, because there are many cancer patients who got the disease with healthy lifestyles. 

The point is no matter what stage and/or type of cancer, there are so many factors to what caused the disease and possible outcomes.

It's time people understood that cancer is a genetic disease, and at all stages blaming a patient for their disease no matter what life style, needs to stop. 

Also within the cancer community, the war of the stages and types needs to stop. 

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Big Pharma Quietly Enlists Leading Professors to Justify $1,000-Per-Day Drugs

Big Pharma Quietly Enlists Leading Professors to Justify $1,000-Per-Day Drugs | Breast Cancer News | Scoop.it
As it readies for battle with President Trump over drug prices, the pharmaceutical industry is deploying economists and health care experts from the nation’s top universities. In scholarly articles, blogs and conferences, they lend their prestige to the lobbying blitz, without always disclosing thei
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This article is long but well worth reading. It makes one wonder why the pharmaceutical industry practices in the US has never been part of the conversation of how we can improve the Affordable Care Act. 

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Revolutionary Israeli device can eliminate need for follow-up breast cancer surgery

Revolutionary Israeli device can eliminate need for follow-up breast cancer surgery | Breast Cancer News | Scoop.it
MarginProbe, which checks tumor's edges while lumpectomy patient is still on operating table, is already in use in over 100 US hospitals
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While the article is overpraising the device as eliminating the need for follow up surgery since no device can ever predict that, it still is a great new tool. 

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Enzymes' Role in Breast Cancers That Are Estrogen Receptor-positive ID'd

Enzymes' Role in Breast Cancers That Are Estrogen Receptor-positive ID'd | Breast Cancer News | Scoop.it
In a study, scientists identified the enzymes LATS1 and LATS2 as key in the development and treatment of estrogen receptor-positive breast cancer.
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Do Screening Mammograms Cut Breast Cancer Deaths Or Lead To Overtreatment? Probably Both

Do Screening Mammograms Cut Breast Cancer Deaths Or Lead To Overtreatment? Probably Both | Breast Cancer News | Scoop.it
A new study of Danish women suggests that screening mammography detects many tumors that might not have ever harmed women.
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So the debate continues about mammograms. This article looks at both sides of the issue,. Rita Rubin writes about the factors where screening could be ineffective, yet recognizing that the biggest problem is that they still don't know which tumors are going to spread. The article also recognizes the metastatic breast cancer problem as the deaths just keep coming.. With MBC we have to do better. 

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Beware of Predatory Cancer Testing Companies

Beware of Predatory Cancer Testing Companies | Breast Cancer News | Scoop.it
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What a terrible cancer scam rip off!
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Irina Bcra's curator insight, December 27, 2016 3:37 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

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Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases

Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases | Breast Cancer News | Scoop.it
Charles Perou and colleagues report on somatic mutations in primary tumors and metastases from two patients with basal-like breast cancer.
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Irina Bcra's curator insight, December 27, 2016 3:37 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

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Trend No. 1 — Cancer MoonShot

Trend No. 1 — Cancer MoonShot | Breast Cancer News | Scoop.it
This historic collaborative initiative aims to accelerate the potential of immunotherapy as the next generation standard of care for cancer.
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Cancer drugs, survival, and ethics

Cancer drugs, survival, and ethics | Breast Cancer News | Scoop.it
Despite considerable investment and innovation, chemotherapy drugs have had little effect on survival in adults with metastatic cancer.
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Irina Bcra's curator insight, December 27, 2016 3:38 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

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‘Bald Ballerina’ Keeps Dancing Through a Double Mastectomy and Treatment for Terminal Breast Cancer

‘Bald Ballerina’ Keeps Dancing Through a Double Mastectomy and Treatment for Terminal Breast Cancer | Breast Cancer News | Scoop.it
“ Maggie Kudirka was just 22 and a ballerina with the Joffrey company when she discovered a lump that turned out to be terminal breast cancer”
Via Librarian@HOPE
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Irina Bcra's curator insight, December 27, 2016 3:38 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

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Breast Cancer Drugs Price Analysis and Strategies Report 2012-2021 - Research and Markets

Breast Cancer Drugs Price Analysis and Strategies Report 2012-2021 - Research and Markets | Breast Cancer News | Scoop.it

Research and Markets has announced the addition of the "Breast Cancer Drugs Price Analysis and Strategies - 2016" report to their offering.

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Irina Bcra's curator insight, December 27, 2016 3:39 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

Irina Bcra's curator insight, January 17, 1:35 AM
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Breast Cancer's Complexity Pushes Researchers to Look Beyond the Genome

Breast Cancer's Complexity Pushes Researchers to Look Beyond the Genome | Breast Cancer News | Scoop.it
Although breast cancer research has helped chart the course for molecularly targeted therapies in oncology, next-generation sequencing technologies have revealed a disease so highly complex and heterogeneous that translating these findings into...
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Male survivors remind us that men get breast cancer, too

Male survivors remind us that men get breast cancer, too | Breast Cancer News | Scoop.it
Newsflash – men have breast tissue, which means they can get breast cancer just like women.
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Irina Bcra's curator insight, December 27, 2016 4:08 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/

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As Drug Costs Soar, People Delay Or Skip Cancer Treatments

As Drug Costs Soar, People Delay Or Skip Cancer Treatments | Breast Cancer News | Scoop.it
Cancer patients increasingly delay or skip taking medication because they can't afford it. New drugs that can cost $100,000 or more a year mean more people suffering "financial toxicity."
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This is so upsetting. The cost of drugs is out of control. 

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This Lingerie Brand Cast Breast Cancer Survivors for Its NYFW Runway

This Lingerie Brand Cast Breast Cancer Survivors for Its NYFW Runway | Breast Cancer News | Scoop.it
Lingerie and loungewear label AnaOno, which caters to breast cancer survivors, showcased the beauty and strength of its clientele on its Spring 2017 runway.
Curated by A4BC.ORG's insight:

So proud of the AnaOno lingerie and loungewear label strutting their stuff on the NYFW Runway catering to breast cancer survivors! 

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Living Beyond Breast Cancer Creates Healthcare Newsroom To Provide Policy Updates

Living Beyond Breast Cancer Creates Healthcare Newsroom To Provide Policy Updates | Breast Cancer News | Scoop.it
PHILADELPHIA, Jan. 26, 2017 /PRNewswire-USNewswire/ --�To help people affected by breast cancer understand and prepare for changes to healthcare insurance policies that might affect them, Living Beyond Breast Cancer (LBBC) has created a
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Check out the great work being done at Living Beyond Breast Cancer 

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Drug trials funded by big pharmas could be biased

Drug trials funded by big pharmas could be biased | Breast Cancer News | Scoop.it
Experts, from the University of California San Francisco, found in 58 per cent of trials the lead investigator had at least some degree of financial tie to the firm that made the drug being tested.
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One Breath Into This Breathalyzer Can Diagnose 17 Diseases

One Breath Into This Breathalyzer Can Diagnose 17 Diseases | Breast Cancer News | Scoop.it
A new breathalyzer can detect 17 different diseases, including pre-eclampsia and chronic kidney disease, from a single breath.
Curated by A4BC.ORG's insight:

To see the original study go to: http://pubs.acs.org/doi/full/10.1021/acsnano.6b04930

 

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‘Miracle Patient’ Finds New Hope with Breast Cancer Vaccine

‘Miracle Patient’ Finds New Hope with Breast Cancer Vaccine | Breast Cancer News | Scoop.it
City of Hope patient Susan Young - diagnosed with late-stage triple negative breast cancer - has had a remarkable response to a revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding...
Curated by A4BC.ORG's insight:
This is truly remarkable. Hopefully it can help more people.
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George Cahill's curator insight, December 21, 2016 4:13 AM
12-21-2016
Irina Bcra's curator insight, December 27, 2016 3:37 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/ 

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Methylation of Gene Panel May Help Predict Breast CA Survival --Doctors Lounge

Methylation of Gene Panel May Help Predict Breast CA Survival --Doctors Lounge | Breast Cancer News | Scoop.it
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Check this out!
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OncoCyte (OCX) Says Poster on Breast Cancer Diagnostic Test to Be Presented at SABCS

OncoCyte (OCX) Says Poster on Breast Cancer Diagnostic Test to Be Presented at SABCS | Breast Cancer News | Scoop.it
OncoCyte (OCX) Says Poster on Breast Cancer Diagnostic Test to Be Presented at SABCS
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Here's an example of liquid biopsy tests to be presented at SABCS.

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Take multiple biopsies in studies of personalised breast cancer treatments, study says

Take multiple biopsies in studies of personalised breast cancer treatments, study says | Breast Cancer News | Scoop.it
Clinicians should take multiple biopsies from patients in clinical trials of targeted breast cancer drugs to avoid missing key mutations with important implications for treatment, new research has found. Genetic profiling of patients' tumours using biopsies has become more common in recent years, helping to drive personalised therapy and ensure that patients receive the treatments most likely to be effective for them.
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Survivorship: Follow-Up Care | The American Society of Breast Surgeons Foundation

Survivorship: Follow-Up Care | The American Society of Breast Surgeons Foundation | Breast Cancer News | Scoop.it
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Novartis breast cancer drug gets FDA fast track, takes on Pfizer

Novartis breast cancer drug gets FDA fast track, takes on Pfizer | Breast Cancer News | Scoop.it

The U.S. Food and Drug Administration gave fast-track review status to Novartis's medication ribociclib in first-line treatment of postmenopausal women with advanced breast cancer as the Swiss company seeks to challenge Pfizer's Ibrance drug.

Curated by A4BC.ORG's insight:

Always wonder when there's a new drug like Novartis' ribocibib  competing with Pfizer's drug Ibrance , does it helps metastatic breast cancer patients by improving the drug? In this article, t's hard to tell. 

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The Case Against The Case Against Mammography

The Case Against The Case Against Mammography | Breast Cancer News | Scoop.it
The overdiagnosis campaign reflects a lack of respect for women’s capacity to act rationally upon receiving an abnormal test result.
Curated by A4BC.ORG's insight:

Great Article by Elaine Schattner, putting a real analysis on the issue for patients. It's shocking they are making this report on mammography based on 2002 data.

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