"UC San Diego Moores Cancer Center researcher says breast cancer in women of Mexican descent occurs despite seemingly protective factors
Scientific data suggest that a woman reduces her risk of breast cancer by breastfeeding, having multiple children and giving birth at a younger age. A study led by the University of California, San Diego School of Medicine and recently published online by Cancer Epidemiology, Biomarkers & Prevention, indicates that women of Mexican descent may not fit that profile. In fact, results suggest that women of Mexican descent with more children and those who breastfeed are more likely to be diagnosed with an aggressive form of breast cancer.
During the four-year Ella Binational Breast Cancer Study, scientists assessed the association between reproductive factors and tumors subtypes in 1,041 Mexican and Mexican-American female cancer patients.
The study looked at the occurrence of three tumor subtypes: luminal A, HER2 and triple negative. The luminal tumor starts in the inner cell lining of the mammary ducts and is most common. The HER2 tumor is so-named because it is positive for human epidermal growth factor receptor 2 (or HER2) – a protein shown to play a role in aggressive breast cancer. Triple negative breast cancer does not have targeted treatment options, making it difficult to treat and giving it the worst prognosis."