"Zhang M, et al. – Triple–negative breast cancer (TNBC) is a particular type of breast cancer which is characterized by its biological aggressiveness, worse prognosis, and lack of prognostic markers or therapeutic targets in contrast with hormonal receptor–positive and human epidermal growth factor receptor 2–positive (HER2+) breast cancers. .
- A total of 136 patients who had undergone a resection of primary TNBC were enrolled at the Third Affiliated Hospital of Harbin Medical University from March 2003 to September 2005.
- Expression of ER, PR, HER2, EGFR, and survivin was assessed by immunohistochemistry.
- The association of TNBC and other clinicopathological variables and the prognostic value of survivin and EGFR expression were evaluated.