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How to End Breast Cancer: A Request

How to End Breast Cancer: A Request | Breast Cancer News | Scoop.it

"I'm just going to come right out and say it: I am beating the odds already. There are all kinds of statistics out there for the survival rates of patients with Stage 4 breast cancer. Most of them are pretty grim.

After all, there is no Stage 5.

And of course I can't remember where I saw it, but I've read a few times that the median survival time once metastases are detected is twenty-six months. That's not that many months. Ask any mother.

Only about one in five people with Stage 4 breast cancer live to see their five-year cancerversary. Go ahead and re-read that sentence. I'll wait for you.

Of course, there are a million factors that determine how any one person will fare -- extent of metastases, responsiveness to treatment, overall health other than cancer, sheer dumb luck, to name a few. So it's nearly impossible to predict accurately how long someone will live once diagnosed with cancer, and my doctors have never given me a timeframe, other to say they can treat this for years."

Susan Zager's insight:

Now that breast cancer awareness month is over, Jennifer Campisano urges everyone in the US to write your Representatives and Senatorsto maintain science research funding levels, specifically the Department of Defense's Breast Cancer Research Program and the National Cancer Institute.

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Research on Vaccines for Breast Cancer Proceeding

None FDA approved to date, but interesting research is ongoing.
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Lots of #research but no FDA approved to date,. The research is ongoing.as we hope for combination vaccines and medications that reverse terminal progression (MBC)
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On the hunt for genetic clues to breast cancers that spread to the brain — UNC Lineberger Comprehensive Cancer Center

On the hunt for genetic clues to breast cancers that spread to the brain — UNC Lineberger Comprehensive Cancer Center | Breast Cancer News | Scoop.it
UNC Lineberger researcher Carey Anders, MD, wants to understand why some breast cancers metastasize to the brain, and what drives them.
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Why Democratic convention viewers saw so many drug ads

Why Democratic convention viewers saw so many drug ads | Breast Cancer News | Scoop.it
Drug makers advertised heavily at the Democratic National Convention to promote their products — and their industry.
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Drug ads have been a major frustration. It wastes huge amounts of money and we pay the price. It's a tough dance when you need drugs to save your life and have to be subjected to their wasting money that could be spent on metastatic research.
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A Modern, Adaptive FDA Should Support Patients' Right To Try New Medications

A Modern, Adaptive FDA Should Support Patients' Right To Try New Medications | Breast Cancer News | Scoop.it
The agency’s leadership might accomplish what medicine does best: applying science humanely, so that people can get well if it’s possible, and not wait.
Susan Zager's insight:
This article by Elaine Schattner looks at the issues with medications and the FDA approvals when patients need certain meds to stay alive.
Here's some great quotes, while we recommend reading the full article.

Elaine writes:
"A little-cited fact is that many of the 97% cancer patients who aren’t on clinical trials aren’t on study because they don’t qualify for a trial. It’s not that they or their doctors don’t want to participate.
Access to life-saving drugs, within the FDA evaluation system, shouldn’t be based on a patient’s wealth or connections. I’m excited about the FDA’s news, establishing an oncology center related to the Cancer Moonshot. This should expedite the careful and informed evaluation and approval of new drugs, diagnostic tools and medical devices. Ihope the efforother diseases".
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Biden holding cancer summit to pump up support for ‘moonshot’ effort

Biden holding cancer summit to pump up support for ‘moonshot’ effort | Breast Cancer News | Scoop.it
Meetings in Washington and around the country Wednesday will focus on research needs.
Susan Zager's insight:
Check out your local areas and also links to live satellite if you can't travel. From USC go to: http://keckmedia.usc.edu/Mediasite/Catalog/catalogs/Cancer-Moonshot-Summit
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21st Century Cures Act nears passage with little news media scrutiny

21st Century Cures Act nears passage with little news media scrutiny | Breast Cancer News | Scoop.it
Veteran health care reporter and regular HealthNewsReview.org blogger Trudy Lieberman has been following the 21st Century Cures Act’s journey through Congr
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Despite ASCO Mishap, Data Still Intriguing for Sacituzumab Govitecan in TNBC | Onclive

Despite ASCO Mishap, Data Still Intriguing for Sacituzumab Govitecan in TNBC | Onclive | Breast Cancer News | Scoop.it
Sacituzumab govitecan (IMMU-132) had an objective response rate of 33% in pretreated patients with triple-negative breast cancer, according to updated findings from a phase II study reported by Immunomedics, the manufacturer of the antibody-drug conjugate.
Susan Zager's insight:

This study was excluded from the conference when ASCO became aware that its meeting embargo had been violated when the chairman of Immunomedics reported the results at a conference in April. Meanwhile the author of this article, Jason Broderick, looks at the important findings. 

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June 4, 2016: Chicago

June 4, 2016: Chicago | Breast Cancer News | Scoop.it
Right Patient, Right Treatment, Right Now Doctors, Patients, Experts and Advocates Help You Survive the Attacks on YOUR Treatments Join us for our CALL TO ACTION: Right Patient, Right Treatment, Right Now FACTS: The Obstacles to Access CLARITY:...
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Looks interesting!
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Compassion & Choices | Medical Aid in Dying Act Wins Swift Assembly Committee Vote

Compassion & Choices | Medical Aid in Dying Act Wins Swift Assembly Committee Vote | Breast Cancer News | Scoop.it
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Hopefully many more states will follow along.
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Antibody appears to attack cancer cells, leaving other cells unscathed

Antibody appears to attack cancer cells, leaving other cells unscathed | Breast Cancer News | Scoop.it

"An antibody has been developed from the body's own immune system that preferentially attacks cancer cells. The antibody works by targeting a natural defense mechanism that cancer tumors exploit. Cells in the body essentially use a home security system that relies on certain proteins to protect the cell surface and keep it safe. These proteins help the cell avoid injury and even death from unwanted activation of the immune system."

Susan Zager's insight:

To see the study go to: http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30465-X

 

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Pembrolizumab Promising in Metastatic Triple-Negative Breast Cancer | Cancer Network

Pembrolizumab Promising in Metastatic Triple-Negative Breast Cancer | Cancer Network | Breast Cancer News | Scoop.it
The KEYNOTE-012 trial shows that pembrolizumab has activity and acceptable toxicity as single-agent therapy in advanced triple-negative breast cancer.
Susan Zager's insight:

To see the original study go to: http://jco.ascopubs.org/content/early/2016/04/27/JCO.2015.64.8931.abstract

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You Pay to Read Research You Fund. That’s Ludicrous

You Pay to Read Research You Fund. That’s Ludicrous | Breast Cancer News | Scoop.it
Saying that Sci-Hub is about copyright infringement is like saying the Boston Tea Party was about late-night vandalism.
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What I Said to the Largest Convening of Cancer Researchers in the Country Yesterday:

What I Said to the Largest Convening of Cancer Researchers in the Country Yesterday: | Breast Cancer News | Scoop.it
Thank you. Thank you very, very much. You’re extremely gracious and generous.
Susan Zager's insight:

Here's a link to @VP Biden speaking about the #moonshot #cancer program. It's very important to stay involved as he spells out the key points in this speech. We must make sure treatment and reserach for Stage IV is part of the molding of this project. This approach can lead to a help real cure for all stages and end deaths from this horrible disease.

This program is for all parties to be involved- so this is not a political statement.

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California senator withdraws drug price transparency bill

California senator withdraws drug price transparency bill | Breast Cancer News | Scoop.it
The decision came after amendments were made during an assembly committee hearing that sources said “effectively gutted” the legislation.
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‘My dog has found 550 cancers.. and he saved my life’: Meet the amazing pooch that sniffs out killer disease

‘My dog has found 550 cancers.. and he saved my life’: Meet the amazing pooch that sniffs out killer disease | Breast Cancer News | Scoop.it
THIS is the dog that can sniff out cancer in seconds – and is revolutionising the way we diagnose the disease
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The sobering thing doctors do when they die

The sobering thing doctors do when they die | Breast Cancer News | Scoop.it
Doctors do the opposite of what they say want to do when they die
Susan Zager's insight:
Fascinating look at doctors and patients choices when dying. It's interesting that the article notes that Doctors usually choose less treatment and longer time in hospice. There is so much pressure to keep doing aggressive drugs that sometimes cause more progression and other side effects that end up being more harmful. Very thought provoking.
To see the original study go to: http://onlinelibrary.wiley.com/doi/10.1111/jgs.14112/abstract
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New technology helps ID aggressive early breast cancer

New technology helps ID aggressive early breast cancer | Breast Cancer News | Scoop.it
Researchers at the University of Michigan developed a new technology that can identify aggressive forms of ductal carcinoma in situ, or stage 0 breast cancer, from non-aggressive varieties.
Susan Zager's insight:

This technology will take time but it's the most no-aggressive way to go.

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Cancer, bankruptcy and death: study finds a link

Cancer, bankruptcy and death: study finds a link | Breast Cancer News | Scoop.it
A new study conducted by Fred Hutch's HICOR group has found that the 3 percent of cancer patients who go bankrupt are more likely to die. We talk to study author Dr. Scott Ramsey.
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We’re spending $107 billion on cancer drugs, but is it worth it?

We’re spending $107 billion on cancer drugs, but is it worth it? | Breast Cancer News | Scoop.it
The wave of new cancer treatments may not lengthen patients' lives much.
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The cost of cancer drugs is growing and expensive. Carolyn Johnson takes an important look on where money is spent and what is getting results as well as where the problems are.

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What You Need to Know About the World's Biggest Cancer Conference

What You Need to Know About the World's Biggest Cancer Conference | Breast Cancer News | Scoop.it
Doctors and biopharma giants will congregate in Chicago on Friday for ASCO's annual meeting, the biggest cancer conference in the business.
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Fighting to tame metastatic breast cancer

Fighting to tame metastatic breast cancer | Breast Cancer News | Scoop.it
As sleety rain kept falling, the activists anguished about whether to go ahead with plans to lie on the ground on a recent Saturday evening. Their "die-in" was intended to symbolize the fact that,
Susan Zager's insight:
Proud to be a part of this DieIn. Great article about many people working to get funding for so many #dyingforacure
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Pictilisib for Estrogen Receptor–Positive, Aromatase Inhibitor–Resistant, Advanced or Metastatic Breast Cancer

Pictilisib for Estrogen Receptor–Positive, Aromatase Inhibitor–Resistant, Advanced or Metastatic Breast Cancer | Breast Cancer News | Scoop.it
Pictilisib for Estrogen Receptor–Positive, Aromatase Inhibitor–Resistant, Advanced or Metastatic Breast Cancer
Susan Zager's insight:

You made need to sign in for the article, but it's worth it. To see the original study go to: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)00106-6/abstract?cc=y=

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Prospects in the Management of Breast Cancer

Prospects in the Management of Breast Cancer | Breast Cancer News | Scoop.it
The panelists, Adam M. Brufsky, MD; Sara A. Hurvitz, MD; Joyce A. O’Shaughnessy, MD; Hope S. Rugo, MD; and Christy A. Russell, MD, share final thoughts on future improvements in the management of breast cancer.
Susan Zager's insight:

Interesting panel discussion including Triple Negative Breast Cancer and MBC

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Beating Cancer: The Real Life Battle for Patients and Their Loved Ones

Beating Cancer: The Real Life Battle for Patients and Their Loved Ones | Breast Cancer News | Scoop.it
Community,news,cure,cure today, cure magazine
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It's time the real facts of Metastatic breast cancer come out. Great article!
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New strides in metastatic breast cancer research give patients hope

New strides in metastatic breast cancer research give patients hope | Breast Cancer News | Scoop.it
Metastatic breast cancer kills around 40,000 women (and men) a year, but a handful of MBC patients who visited Fred Hutch recently say they're more encouraged than ever. Find out why.
Susan Zager's insight:

Check out this great article and Beth Caldwell's input. It also speaks about the #MBCProject

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