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Heating up breast cancer

Heating up breast cancer | breast cancer | Scoop.it

"FRESNO, Calif. (KFSN) --

Two years ago, doctors told Lisa Ridgeway she had triple negative breast cancer, a very aggressive disease with no cure.

"There are not a lot of drugs that work, or work for a long period of time," Ridgeway told ABC30.

The mom of two was facing a typical life expectancy of just three years.

"That's a mom's horror story, knowing that you aren't going to be here," she said.

Lisa had surgery, radiation, and chemo, but her cancer came back two more times. Now she's trying something new.

Doctors at the Cleveland Clinic are offering patients hyperthermia treatment.

"Hyperthermia is heat therapy. It's actually been around since the time of the Egyptians," Jennifer Yu, MD, Radiation Oncologist at Cleveland Clinic, told ABC30.

A hot bag is placed on top of the skin. A microwave unit heats the bag and the tissue under it to about 110 degrees. The heat increases blood flow and makes tumors more sensitive to radiation.

"And it improves cell kill," Dr. Yu said.

In one study, 66 percent of cancer patients who had hyperthermia and radiation had their tumors shrink completely compared to just 42 percent who had only radiation.

Lisa hopes the treatment will give her more time.

"My choice is I want to live," she said."


Via Susan Zager
Miiko Mentz's insight:

Hyperthermia, a heat therapy, combined with radiation therapy has been shown to improve the effectiveness of radiation. "In one study, 66 percent of cancer patients who had hyperthermia and radiation had their tumors shrink completely compared to just 42 percent who had only radiation."

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Susan Zager's curator insight, June 18, 2014 4:13 PM

According to the article, there are about 10 centers around the country using hyperthermia for breast cancer. 


If you would like more information, please contact:

Tora Vinci
Media Relations Manager
Cleveland Clinic
vinciv@ccf.org

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Rescooped by Miiko Mentz from Breast Cancer News
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Heating up breast cancer

Heating up breast cancer | breast cancer | Scoop.it

"FRESNO, Calif. (KFSN) --

Two years ago, doctors told Lisa Ridgeway she had triple negative breast cancer, a very aggressive disease with no cure.

"There are not a lot of drugs that work, or work for a long period of time," Ridgeway told ABC30.

The mom of two was facing a typical life expectancy of just three years.

"That's a mom's horror story, knowing that you aren't going to be here," she said.

Lisa had surgery, radiation, and chemo, but her cancer came back two more times. Now she's trying something new.

Doctors at the Cleveland Clinic are offering patients hyperthermia treatment.

"Hyperthermia is heat therapy. It's actually been around since the time of the Egyptians," Jennifer Yu, MD, Radiation Oncologist at Cleveland Clinic, told ABC30.

A hot bag is placed on top of the skin. A microwave unit heats the bag and the tissue under it to about 110 degrees. The heat increases blood flow and makes tumors more sensitive to radiation.

"And it improves cell kill," Dr. Yu said.

In one study, 66 percent of cancer patients who had hyperthermia and radiation had their tumors shrink completely compared to just 42 percent who had only radiation.

Lisa hopes the treatment will give her more time.

"My choice is I want to live," she said."


Via Susan Zager
Miiko Mentz's insight:

Hyperthermia, a heat therapy, combined with radiation therapy has been shown to improve the effectiveness of radiation. "In one study, 66 percent of cancer patients who had hyperthermia and radiation had their tumors shrink completely compared to just 42 percent who had only radiation."

more...
Susan Zager's curator insight, June 18, 2014 4:13 PM

According to the article, there are about 10 centers around the country using hyperthermia for breast cancer. 


If you would like more information, please contact:

Tora Vinci
Media Relations Manager
Cleveland Clinic
vinciv@ccf.org

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Time to debunk the mammography myth

Time to debunk the mammography myth | breast cancer | Scoop.it
Gayle Sulik and Bonnie Spanier say the benefits of regular mammograms have been greatly exaggerated and the hazards largely ignored
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Vitamin D Increases Breast Cancer Patient Survival

Vitamin D Increases Breast Cancer Patient Survival | breast cancer | Scoop.it

"Breast cancer patients with high levels of vitamin D in their blood are twice as likely to survive the disease as women with low levels of this nutrient, report University of California, San Diego School of Medicine researchers in the March issue of Anticancer Research.

In previous studies, Cedric F. Garland, DrPH, professor in the Department of Family and Preventive Medicine, showed that low vitamin D levels were linked to a high risk of premenopausal breast cancer. That finding, he said, prompted him to question the relationship between 25-hydroxyvitamin D—a metabolite produced by the body from the ingestion of vitamin D—and breast cancer survival rates.

Garland and colleagues performed a statistical analysis of five studies of 25-hydroxyvitamin D obtained at the time of patient diagnosis and their follow-up for an average of nine years. Combined, the studies included 4,443 breast cancer patients.

“Vitamin D metabolites increase communication between cells by switching on a protein that blocks aggressive cell division,” said Garland. “As long as vitamin D receptors are present tumor growth is prevented and kept from expanding its blood supply. Vitamin D receptors are not lost until a tumor is very advanced. This is the reason for better survival in patients whose vitamin D blood levels are high.”

Women in the high serum group had an average level of 30 nanograms per milliliter (ng/ml) of 25-hydroxyvitamin D in their blood. The low group averaged 17 ng/ml. The average level in patients with breast cancer in the United States is 17 ng/ml."


Via Susan Zager
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Rescooped by Miiko Mentz from Breast Cancer News
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Report: Cancer will be No. 1 killer in U.S.

Report: Cancer will be No. 1 killer in U.S. | breast cancer | Scoop.it

"(CNN) -- In 16 years, cancer will become the leading cause of death in the United States, surpassing heart disease, according to a new report from the American Society of Clinical Oncology. The number of new cancer cases is expected to increase nearly 45% by 2030, from 1.6 million cases to 2.3 million cases annually.

This influx of new patients will place a bigger burden on a field of medicine already stretched by physician shortages and financial difficulties, says the report, which highlights growing problems for cancer care in the United States.

Dr. Jeffery Ward knows these issues well. When he joined a community oncology practice in Seattle, it had three doctors. A few years later the group merged with another practice, and connected with a national network of community doctors that enabled them to invest in new technologies and receive group discounts on cancer drugs.

In return, they paid a percentage of their practice's profit to the network.


Cancer rate jump predicted


WHO urges cancer prevention, govt. role

Over time, the doctors' profit margins became slimmer. They couldn't compete with hospitals in the area for radiation therapy and other services that would have diversified their practice, and insurers had the upper hand in contract negotiations.

It became obvious, as Ward said, "that 0% of zero would be zero." So Ward and his colleagues decided to leave the community oncology network and join a large hospital system in Seattle.


Via Susan Zager
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Susan Zager's curator insight, March 11, 2014 6:23 PM

Well worth the read and watching the videos. 

"STORY HIGHLIGHTS
  • Oncology group releases report: "The State of Cancer Care in America"
  • Number of new cases is expected to increase nearly 45% by 2030
  • Smaller community oncology practices being absorbed by larger networks
  • Patients having to travel farther and pay more for cancer services"
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New Advances In Breast Cancer Treatment

New Advances In Breast Cancer Treatment | breast cancer | Scoop.it

"A public release from the Society of Interventional Radiology’s Annual Scientific Meeting highlights a new, groundbreaking treatment modality for metastatic breast cancer that has spread to the liver.

The outpatient procedure, called yttrium-90 (Y-90) radioembolization, involves gliding a catheter through a small incision in the groin area into the artery that supplies blood to the liver. Once in place, the catheter releases small microbeads that target the cancer. The beads embed themselves into the tumor and release concentrated radiation, killing the tumor but sparing the surrounding tissue.

The treatment was analyzed after use on 75 women with metastatic breast cancer whose liver tumors did not respond to normal treatments such as chemotherapy and tumor resection. Of the 69 patients who came in for a follow up, 98.5% showed a stabilization of their tumor, and 24 had at least a 30% reduction in their tumor size.

“While patient selection is important, the therapy is not limited by tumor size, shape, location or number, and it can ease the severity of disease in patients who cannot be treated effectively with other approaches,” said Robert J. Lewandowski, M.D., FSIR, associate professor of radiology at Northwestern University Feinberg School of Medicine in Chicago.

This presentation comes on the heels of a study published last week (March 17th) in Clinical Genetics, in which researchers sought to personalize the genetic makeup of breast cancers in the same way that lung and colon cancers can be genetically tested to determine the appropriate treatment. “Molecular profiling exposes a tumor’s Achilles heel. We can see what messages the tumor cells are receiving and sending. It is a biological intelligence gathering mission in an attempt to interrupt the disease,” says Gregory Tsongalis, PhD, director of Molecular Pathology at Norris Cotton Cancer Center.


Via Susan Zager
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Susan Zager's curator insight, March 26, 2014 7:16 PM

This is new treatment for metastatic breast cancer that has spread to the liver called yttrium-90 (Y-90) radioembolization. It is an out-patient procedure and according to the article, "The treatment was analyzed after use on 75 women with metastatic breast cancer whose liver tumors did not respond to normal treatments such as chemotherapy and tumor resection. Of the 69 patients who came in for a follow up, 98.5% showed a stabilization of their tumor, and 24 had at least a 30% reduction in their tumor size." To see this Y-90 study that "shows minimally invasive treatment that may slow disease progression in the liver while maintaining quality of life" go to: http://www.eurekalert.org/pub_releases/2014-03/soir-ypn031114.php

 

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Ruling helps rein in the Wild West of genetic testing

Ruling helps rein in the Wild West of genetic testing | breast cancer | Scoop.it
On Monday, a U.S. District Court judge in Utah decided that Myriad Genetics could not stop a competitor, Ambry Genetics, from offering commercial BRCA testing as their current legal suit about "breast cancer testing" winds through the courts. Many people rightly wonder how Myriad can sue other companies for patent infringement after the Supreme Court unanimously ruled in June 2013 that patents on human genes are illegal, thus ending Myriad's long-standing monopoly on the BRCA genes. Not only have the courts pushed back on Myriad's monopoly, at the end of 2013 the Food and Drug Administration moved to stop the direct-to-consumer genetic testing company 23&Me from marketing and selling its DNA testing service without approval.
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Yoga Could Improve Quality Of Life For Women With Breast Cancer

Yoga Could Improve Quality Of Life For Women With Breast Cancer | breast cancer | Scoop.it

"Yoga may help combat pain, fatigue and depression among women battling breast cancer, according to a recent study Medical

News Today reported. Researchers found that yoga may ease some of the side effects of radiation therapy, one of the main treatments from cancer, by regulating stress hormones, improving quality of life beyond treatment, Medical News Today reported.

"The benefits of yoga are above and beyond stretching," Lorenzo Cohen, a professor of oncology at M.D. Anderson Cancer Center in Houston and lead author of the study published Monday in the Journal of Clinical Oncology, told ABC News. "These findings may improve outcomes in cancer survivors."

For the study, researchers randomly assigned 191 women with breast cancer who were undergoing radiation therapy into one of three groups. One group did yoga, another did simple stretching exercises, and a third group did neither. The participants in the yoga and stretching groups attended sessions for one hour, three days a week throughout the six weeks of their radiation therapy.

Women in the yoga group reported a reduction in fatigue, whereas the women in the other two groups did not. They also reported better general health and functioning at 1,3, and 6 months after radiation treatment."


Via Susan Zager
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