Brain Tumors
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Stanford scientists build a microscope to spot the seeds of cancer

Stanford scientists build a microscope to spot the seeds of cancer | Brain Tumors | Scoop.it

One of the cruelest truths about cancer is that even after you beat the disease, it can still come back to kill you. A tumor growing in the prostate gland, breast, or any other organ can shed cancerous cells into the blood. These cancerous seeds travel the body and can take root nearly anywhere, growing into a new cancer threat even after the initial cancer is treated.

 

The rule of thumb with cancer is that the earlier you can detect the disease, the more effective the treatment, and hence better potential outcomes.

 

Currently, doctors draw a patient's blood and analyze it using special antibodies to detect the presence of the seeds, called circulating tumor cells (CTCs). This works well if CTCs are present in large numbers, but may fail to detect smaller numbers released by earlier tumors.

 

Now, a team of engineers, scientists and doctors from Stanford is developing a mini-microscope that might be able to noninvasively detect the CTCs earlier than ever, allowing for earlier interventions.

 

"There has been a huge push to increase sensitivity," said Bonnie King, an instructor at Stanford School of Medicine. "We suspect that CTCs often circulate in numbers below our current threshold of detectability."

 

A major advantage with the microscopic technique, King said, is the ability to screen much larger volumes of blood, rather than just a small vial collected from a patient. This will be done using a method called in vivo flow cytometry – a laser-based technology for counting cells in a live subject.

 
Via nrip
Pacific Cove's insight:

The rule of thumb with cancer is that the earlier you can detect the disease, the more effective the treatment, and hence better potential outcomes.

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Mohamed Haroon's curator insight, October 4, 2013 12:26 AM

Interesting Techonology - 

jacob kleboe's curator insight, October 6, 2013 5:27 AM
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Brain Tumors
Brain Cancer Awareness - #BrainTumorThursday - #BrainCancer - Diffuse Intrinsic Pontine Glioma (DIPG) - Glioblastoma
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Kids share heartbreaking photo of their terminally ill parents after they die just days apart

Kids share heartbreaking photo of their terminally ill parents after they die just days apart | Brain Tumors | Scoop.it
Thousands of strangers rally around 3 siblings after their parents die within 5 days of each other
Pacific Cove's insight:
Mike, a cabinetmaker who loved to make wood furniture, had been fighting a brain tumor. He tried every treatment doctors suggested, but the tumor kept growing. Julie, a primary school teacher, was diagnosed with kidney and liver cancer. The cancer spread “everywhere,” #BrainTumor #Cancer
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'My Headaches Turned Out To Be Brain Cancer’

'My Headaches Turned Out To Be Brain Cancer’ | Brain Tumors | Scoop.it
When one woman's headache turned out to be a brain tumor, she learned to look at life with a very different perspective.
Pacific Cove's insight:
As soon as the technicians saw my scan, they took me immediately to the ER at the hospital next door. My doctor came in and told me I had a brain tumor in my left temporal lobe, the part that processes speech and vision. #BrainTumor #BrainTumorThursday
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'Tumor paint' helps surgeons remove brain tumors safely

'Tumor paint' helps surgeons remove brain tumors safely | Brain Tumors | Scoop.it
Doctors at Seattle Children's Hospital are currently studying the safety of using tumor paint to highlight significant areas of the brain.
Pacific Cove's insight:
The family agreed to allow Hunter to be part of a study that would light up his tumor during surgery using tumor paint. By using a molecule in scorpions that binds to cancerous tumors, Dr. Jim Olson created a drug that makes the cancer stand out for surgeons. #BrainCancer #BrainTumorThursday
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7-Year-Old with Brain Cancer Meets His Favorite Superhero Inside Actual Batcave: ‘It Made My Heart Melt,’ Says Mom

7-Year-Old with Brain Cancer Meets His Favorite Superhero Inside Actual Batcave: ‘It Made My Heart Melt,’ Says Mom | Brain Tumors | Scoop.it
Ty Verbanas was diagnosed with a brain tumor just two weeks ago.
Pacific Cove's insight:
The young boy was diagnosed with a brain tumor just two weeks ago. Doctors planned emergency surgery and told his mom they weren’t sure how he’d do or if he’d even survive it. Mary posted about Ty’s love for Batman on Facebook, begging anyone to help her “introduce” her son to Batman before he had to undergo the risky surgery. #BrainCancer #BrainTumorThursday
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Duke Clinical & Translational Science Institute

Duke Clinical & Translational Science Institute | Brain Tumors | Scoop.it
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“We can put the tumors in culture and keep them going for days or weeks,” Lo said. “Now we can watch the tumor grow in the normal brain environment, but because it’s in dish we can also examine them carefully, both by digital imaging and by molecular analysis.” #BrainTumorThursday #BrainCancer #BrainTumor
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Targeted radiosurgery better than whole-brain radiation for treating brain tumors

Targeted radiosurgery better than whole-brain radiation for treating brain tumors | Brain Tumors | Scoop.it

Tumors that originate in other organs of the body and spread to the brain are known as metastatic brain tumors. According to the American Brain Tumor Association, this tumor type is the most common in adults, affecting as many as 300,000 people each year." 

Pacific Cove's insight:
University of Missouri School of Medicine researchers compared two common postsurgical therapies for metastatic brain tumors and found that stereotactic radiosurgery can provide better outcomes for patients compared to whole-brain radiation.  #BrainTumorThursday 
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Family who lost daughter to liver cancer learns 9-year-old son has a brain tumor

Family who lost daughter to liver cancer learns 9-year-old son has a brain tumor | Brain Tumors | Scoop.it
A Rockwall family that has already suffered tragedy from cancer is once again facing a tough challenge. In mid-January, The Martell family got the frightening news at Children’s Medical Cente
Pacific Cove's insight:
Less than a year later on January 12th, her family was hit with yet another challenge, learning Luna’s 9-year-old step brother Simran has a brain tumor.  #BrainTumorThursday
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Childhood Cancer Part 2: Alissa Battles a Brain Tumor

Childhood Cancer Part 2: Alissa Battles a Brain Tumor | Brain Tumors | Scoop.it
According to the American Childhood Cancer Association, each year in the United States, about 16,000 children are diagnosed with cancer before the age of 19.
Pacific Cove's insight:
Doctors found a cyst, the size of a golf ball on the back of Alissa's brain. A cancerous tumor called medulloblastoma. Leah says the hardest part was not whether to start treatment, but it was deciding which treatment is going to be best for Alissa. #BrainTumor #BrainCancer #BrainTumorThursday
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Miami Dolphins employee’s life is saved by a BRAIN TUMOR

Miami Dolphins employee’s life is saved by a BRAIN TUMOR | Brain Tumors | Scoop.it
Joel Adams, 29, the Miami Dolphins' director of business development, went to the doctor last summer to complain of hearing loss out of his right ear. Soon after, a brain tumor was discovered.
Pacific Cove's insight:
Adams, 29, had complained to a doctor that he was experiencing hearing loss in his right ear, according to the Miami Herald. When the doctor ordered an MRI, he discovered a 'tennis-ball sized tumor' attached to his brain. #BrainTumor #BrainCancer #BrainTumorThursday
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Why doctors may keep a patient awake for brain surgery

Why doctors may keep a patient awake for brain surgery | Brain Tumors | Scoop.it
A rare look at brain surgery with the patient alert and awake at Smilow Cancer Hospital at Yale-New Haven.
Pacific Cove's insight:
“The more tumor you remove the better outcome the patient has,” said Moliterno. Taking a more aggressive approach like Awake Craniotomy, Dr. Moliterno says, is a growing trend among those experienced, armed with high-tech tools, all done with the patient’s safety in mind. #BrainCancer #BrainTumor #BrainTumorThursday
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NYPD Deputy Chief James Molloy dies of 9/11-related brain cancer

NYPD Deputy Chief James Molloy dies of 9/11-related brain cancer | Brain Tumors | Scoop.it
The NYPD chief died after a long struggle with the disease, officials said Tuesday. Molloy was 55.
Pacific Cove's insight:
About 31 months ago, Molloy began having vision problems and was diagnosed with a brain tumor. He had surgery that appeared to be successful, but the cancer returned, #BrainCancer #BrainTumor #BrainTumorThursday
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Brain Cancer Treatment: New Drug To Stop Tumor Growth

Brain Cancer Treatment: New Drug To Stop Tumor Growth | Brain Tumors | Scoop.it
Research reveals that chemotherapy drug, mithramycin can stop the growth of aggressive brain cancer tumors. However, repurposing mithramycin to treat brain tumors could take several years
Pacific Cove's insight:
Brain cancer is among the deadliest type of cancer. Glioblastomas particularly are very aggressive and malignant. Median survival rate among brain cancer patients receiving treatment is about two to three years. #BrainTumorThursday #BrainCancer #BrainTumor
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Family's heartbreak as 'beautiful' five-year-old girl dies from brain tumour

Family's heartbreak as 'beautiful' five-year-old girl dies from brain tumour | Brain Tumors | Scoop.it
Little Phoebe Florence Read brought 'nothing but joy and happiness' to everyone who met her, her family say
Pacific Cove's insight:
Little Phoebe Florence Read, from Swansea, Wales, was diagnosed with the inoperable diffuse intrinsic pontine glioma (DIPG) in October last year.#BrainCancer #BrainTumorThursday #DIPG
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Click here to support #TeamJay by Deanna Marquez

Click here to support #TeamJay by Deanna Marquez | Brain Tumors | Scoop.it
#TeamJay by Deanna Marquez - On Thursday March 9, 17 our world took at turn in the wrong direction! Alex and Pearl rushed my 4 month old twin neice Jayleen to CHOC due to noticing her left eye had been bothering her. For a while now we all had a feeling something was wrong with her eye by the way it looked and how Jay wa
Pacific Cove's insight:
Jay was seen at the hospital, right away she was diagnosed with Retinoblastoma not only was it her left eye it was both eyes! Bilateral Retinoblastoma is a rare form of eye cancer that begins in the back of the eye. The cancer begins when cells begin to grow out of control. Sadly for Jay her left eye had a large tumor behind it that was about to spread to the nerve, so she had to have it removed.
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Girl battling brain cancer finishes radiation

Girl battling brain cancer finishes radiation | Brain Tumors | Scoop.it

Her father, Harold Brill, described the end of the radiation treatment for his 9-year-old daughter as “pretty bittersweet.”The treatments caused her to sleep anywhere from 12 to 16 hours a day.

Pacific Cove's insight:
Ciara was diagnosed with DIPG, or diffuse intrinsic pontine glioma, right around Christmas. DIPG is a brain tumor found in a part of the brain stem called the pons. It is an aggressive brain tumor, for which there is no cure, Brill has said. It is typically a terminal diagnosis. #BrainTumor #BrainTumorThursday
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6-year-old battling brain tumor becomes police chief

6-year-old battling brain tumor becomes police chief | Brain Tumors | Scoop.it
6-year-old battling brain tumor becomes police chief
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A young boy battling a battling a rare brain tumor had his dream come true when he got to be police chief for the day at the Framingham Police Department in Massachusetts. #BrainCancer #BrainTumorThursday
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6-year-old's snowboarding injury leads to inoperable brain tumor diagnosis

6-year-old's snowboarding injury leads to inoperable brain tumor diagnosis | Brain Tumors | Scoop.it
For the family of 6-year-old Devin Suau, every day is a race against the clock.
Pacific Cove's insight:
Devin was given between eight months and two years to live after being diagnosed with an inoperable brain tumor for which there is no known cure: diffuse intrinsic pontine giloma (DIPG). #BrainCancer #BrainTumorThursday
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Boy,7, fighting rare brain tumor gets support from strangers

Boy,7, fighting rare brain tumor gets support from strangers | Brain Tumors | Scoop.it
A local 7-year-old is fighting a rare brain tumor in the brain stem called DIPG.
Pacific Cove's insight:
The second-grader was diagnosed last month with a rare brain tumor called DIPG. His mother said the doctor told her only about 200-300 children are diagnosed each year with it. It’s a tumor in the brain stem which controls most functions like breathing. #BrainTumorThursday #DIPG #BrainCancer
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Going out like fireworks: A reporter investigates his own illness — brain cancer | Life | Dallas News

Going out like fireworks: A reporter investigates his own illness — brain cancer | Life | Dallas News | Brain Tumors | Scoop.it
What I’ve learned about fighting glioblastoma — and the specific strategies I used to learn it — could be useful to people dealing with lots of other serious illnesses.
Pacific Cove's insight:
In December, I discovered I had a tumor the size of a chicken egg squashing the lower left side of my brain. I had a relatively successful surgery a couple of days after that semi-coherent Facebook post.  #BrainTumorThrusday 
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Scientists Mimic Rabies to Zap Brain Tumors

Scientists Mimic Rabies to Zap Brain Tumors | Brain Tumors | Scoop.it
Scientists are experimenting with rabies' unique method of killing brain tissue via nerve cells to find out if the pathway can be a conduit for nanoparticles which could zap brain tumors.
Pacific Cove's insight:
Rabies works its way to the brain by way of nerve cells, which effectively skirts the blood-brain barrier, a membrane that is impassable by most other pathogens — but also impassable by cancer drugs, making brain tumors deadly.  #BrainTumor #BrainCaner #BrainTumorThursday
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Yale: Analysis of brain tumor prolongs woman’s life

Yale: Analysis of brain tumor prolongs woman’s life | Brain Tumors | Scoop.it
The researchers were able to extend the findings on this case to more than 100 other glioblastoma cases, leading to the observation that most tumors change their genomic profile during therapy. “These findings have significant implications for precision treatment of these tumors” said Dr. Zeynep Erson Omay
Pacific Cove's insight:
An analysis of a patient’s deadly brain tumor helped doctors at Yale New Haven’s Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for roughly four times longer than her prognosis predicted, researchers report in the journal Genome Medicine. #BrainCancer #BrainTumor #BrainTumorThursday
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A young boy, a devastating brain tumor and parents who ‘will do anything’

A young boy, a devastating brain tumor and parents who ‘will do anything’ | Brain Tumors | Scoop.it
8-year-old Elijah and his family veer from experimental treatments in Germany to a Star Wars welcome back home.
Pacific Cove's insight:
DIPG - Diffuse intrinsic pontine glioma is a doubly devastating tumor: Not only is it in­trac­table, infiltrating the brainstem in a way that makes surgery impossible, but it affects only young children. #DIPG #BrainTumor #BrainCancer #BrainTumorThursday
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Brave Marathoner With Brain Cancer, Known for Running in a Tutu, Dies

Brave Marathoner With Brain Cancer, Known for Running in a Tutu, Dies | Brain Tumors | Scoop.it
Monika Allen (right), running with her friend Tara Baize in 2013, has died of brain cancer. Monika Allen, a girls-empowerment advocate and long-distance runner of great courage, who ran a marathon while receiving chemo treatment for brain cancer, has died of the disease. “I’ll never be in remission
Pacific Cove's insight:
“I’ll never be in remission, so I’m just living day to day,” Allen told Katie Couric about her inoperable brain tumor in 2014, on what was then the Yahoo anchor’s daytime talk show, Katie.  #BrainCancer #BrainTumor #BrainTumorThursday
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Girl, 5, diagnosed with brain cancer after feeling a slight headache

Girl, 5, diagnosed with brain cancer after feeling a slight headache | Brain Tumors | Scoop.it
Rylee Bernosky, 5, from Florida, went to the hospital complaining of a headache. Doctors found a rare brain tumor. She is now looking a 6-8 months of chemotherapy and radiation.
Pacific Cove's insight:
When five-year-old Rylee Bernosky first started complaining of headaches and nausea last month, her parents assured her it would pass. But one evening, a week before Christmas, the headaches started coming on stronger, hitting in waves of 15-20 minutes. #BrainTumorThursday #BrainCancer #BrainTumor
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Brain Cancer Patients Survive Longer by Sending Electric Fields Through Their Heads

Brain Cancer Patients Survive Longer by Sending Electric Fields Through Their Heads | Brain Tumors | Scoop.it
Novocure's gear for treating brain cancer with electric fields includes adhesive electrode patches and a battery pack.
Pacific Cove's insight:
Every few days her husband helps her switch out the adhesive patches that hold the electrodes, which requires reshaving her head, making sure the skin of her scalp is healthy, and applying the new patches. #BrainCancer #BrainTumor #BrainTumorThursday
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