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Stanford scientists build a microscope to spot the seeds of cancer

Stanford scientists build a microscope to spot the seeds of cancer | Brain Tumors | Scoop.it

One of the cruelest truths about cancer is that even after you beat the disease, it can still come back to kill you. A tumor growing in the prostate gland, breast, or any other organ can shed cancerous cells into the blood. These cancerous seeds travel the body and can take root nearly anywhere, growing into a new cancer threat even after the initial cancer is treated.

 

The rule of thumb with cancer is that the earlier you can detect the disease, the more effective the treatment, and hence better potential outcomes.

 

Currently, doctors draw a patient's blood and analyze it using special antibodies to detect the presence of the seeds, called circulating tumor cells (CTCs). This works well if CTCs are present in large numbers, but may fail to detect smaller numbers released by earlier tumors.

 

Now, a team of engineers, scientists and doctors from Stanford is developing a mini-microscope that might be able to noninvasively detect the CTCs earlier than ever, allowing for earlier interventions.

 

"There has been a huge push to increase sensitivity," said Bonnie King, an instructor at Stanford School of Medicine. "We suspect that CTCs often circulate in numbers below our current threshold of detectability."

 

A major advantage with the microscopic technique, King said, is the ability to screen much larger volumes of blood, rather than just a small vial collected from a patient. This will be done using a method called in vivo flow cytometry – a laser-based technology for counting cells in a live subject.

 
Via nrip
Pacific Cove's insight:

The rule of thumb with cancer is that the earlier you can detect the disease, the more effective the treatment, and hence better potential outcomes.

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Mohamed Haroon's curator insight, October 4, 2013 12:26 AM

Interesting Techonology - 

jacob kleboe's curator insight, October 6, 2013 5:27 AM
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Brain Tumors
Brain Cancer Awareness - Diffuse Intrinsic Pontine Glioma (DIPG) - Glioblastoma
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Terminally ill boy from Florida travels to NY to raise money for local ... - wwlp.com

Terminally ill boy from Florida travels to NY to raise money for local ... - wwlp.com | Brain Tumors | Scoop.it
A little boy from Florida was back in the Capital Region on Thursday for a second time to see the snow and give back to a local organization…
Pacific Cove's insight:

#BrainTumorThursday - In 2013 he was diagnosed with a rare and incurable brain tumor known as Diffuse Intrinsic Pontine Glioma or DIPG. He was given 9 months to a year to live.   Ryder does have a Facebook page called “Fight For Ryder” where you can follow his journey: https://www.facebook.com/FightforRyder    #BrainCancer #BrainTumor #BTSM 

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Novel drug mechanism that fights brain cancer

Novel drug mechanism that fights brain cancer | Brain Tumors | Scoop.it
Researchers at UC Davis have developed and characterized a molecule that interferes with the internal regulation of cancer cells, causing them to self-destruct. This…
Pacific Cove's insight:

#BrainTumorThursday - “We are hopeful that this new class of drug will one day become an important adjunct to conventional therapies in fighting these especially difficult-to-treat cancers.”  #BrainCancer #BrainTumor #BTSM 

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Man Celebrates 108th Birthday and 82 Years of Marriage to 104-Year-Old

Man Celebrates 108th Birthday and 82 Years of Marriage to 104-Year-Old | Brain Tumors | Scoop.it
On Saturday, Duranord Veillard of Spring Valley, N.Y., marks the twin milestone with his wife, Jeanne.
Pacific Cove's insight:

During an early birthday celebration Thursday at the couple’s home, Jeanne recounted to USA Today how they met.  “I found him in the street,” she joked in Haitian creole to a room full of relatives, the news outlet writes. #Senior #SeniorCare #Caregiving #Caregivers

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Deputy with brain cancer now unemployed

Deputy with brain cancer now unemployed | Brain Tumors | Scoop.it
A Palm Beach County sheriff's deputy who has been fighting brain cancer for more than a year retired on Tuesday but he said he didn't want to.
Pacific Cove's insight:

#BrainTumorThursday   -  Then, in October of 2014, doctors found another brain tumor which led to another surgery. Through it all, Monti has fought and he's turned his "six months to live" into 13 months and counting. #BrainCancer #BrainTumor #BTSM 

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New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme | Brain Tumors | Scoop.it
There are no effective available treatments for sufferers of Glioblastoma multiforme (GBM), the most aggressive and devastating form of brain tumor. The disease, always fatal, has a survival rate of only 6-18 months.
Pacific Cove's insight:

#BrainTumorThursday - "Unfortunately, gene therapy, bacterial toxin therapy, and high-intensity focused ultrasound therapy had all failed as approaches to treat malignant brain tumors," said Dr. Cohen.  #BrainCancer #BrainTumor #BTSM #

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Darren Daulton passes along good news in battle against brain cancer - CBSSports.com

Darren Daulton passes along good news in battle against brain cancer - CBSSports.com | Brain Tumors | Scoop.it
Former Phillies catcher Darren Daulton passed along good news on Thursday as he battles a "highly malignant" form of brain cancer.
Pacific Cove's insight:

#BrainTumorThursday - It goes without saying this is outstanding news. Daulton's fight is not over, he is battling a severe form of brain cancer, but right now things are looking good. Let's hope this continues.  #BrainCancer #BrainTumor  #BTSM #Caregiving


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UPDATE: Lexie's legacy - Lexie Seaver, died last Sunday after a four-year battle with brain cancer.

UPDATE: Lexie's legacy - Lexie Seaver, died last Sunday after a four-year battle with brain cancer. | Brain Tumors | Scoop.it
On Saturday, loved ones and community members celebrated the life of Lexie Seaver, who died last Sunday after a four-year battle with brain cancer.
Pacific Cove's insight:

#BrainTumorThursday - The 30-year-old Janesville resident was known by many for her decision not to seek treatment for cancer, and instead choosing to live life to the fullest. She feared radiation would prevent her from doing the things she loved to do. #BrainCancer

#BrainTumor #BTSM #Caregiving

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Living Life In Full: The One in Which I Thank the Carson Family & Say Good-bye to One of Our Own

Living Life In Full: The One in Which I Thank the Carson Family & Say Good-bye to One of Our Own | Brain Tumors | Scoop.it
RT @joonbuggirl: Living Life In Full: The One in Which I Thank the Carson Family & Say G... http://t.co/wgOALqr8LS #btsm #braintumorThursda…
Pacific Cove's insight:

#BrainTumorThursday - Unfortunately, that was the end of my first new cycle of chemotherapy with the higher dosage, and I was/am still trying to work it out. (It's almost a week later, and I will don't feel 100% yet....) #BrainCancer #BrainTumor #BTSM #Caregiving 

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Personalized T cell therapy shows promise in stopping brain tumor growth - UPI.com

Personalized T cell therapy shows promise in stopping brain tumor growth - UPI.com | Brain Tumors | Scoop.it
Scientists have proven successful in engineering immune cells to track down and attack glioblastomas, the most common and aggressive type of brain tumor.
Pacific Cove's insight:

#BrainTumorThursday - While the cancer-hunting T cells weren't enough to thwart cancer alone, when mice with human brain tumors were treated simultaneously with chemotherapy and targeted T cell therapy, researchers were able to control the growth of the glioblastomas.  #BrainCancer #BrainTumor @BTSM #Glioblastomas #Caregiving 

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DIPG Angels - The Cristian Rivera Foundation

DIPG Angels - The Cristian Rivera Foundation | Brain Tumors | Scoop.it
The Cristian Rivera Foundation is a New York City based not-for-profit organization, founded in memory of Cristian Rivera, that is committed to finding a cure for Pontine Glioma through education and program funding.
Pacific Cove's insight:

#BrainTumorThursdy - After the doctors examined Cristian and reviewed his MRI, Cristian's mother and father received the worst news of our lives.   The tumor was inoperable and the average lifespan for a child with Pontine Glioma after diagnosis is 3 to 18 months.  #BrainCancer #BrainTumor #BTSm #Caregiving 

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Lauren Hill's team held its end-of-season banquet in hospital

Lauren Hill's team held its end-of-season banquet in hospital | Brain Tumors | Scoop.it
Lauren Hill's Mount Saint Joseph teammates held their end-of-season banquet at the hospital so she could attend. Hill, who has inoperable brain cancer, scored in her first college basketball game...
Pacific Cove's insight:

#BrainTumorThursday - "Day by day, I hope my message has resided through everyone — that just even more that it's precious every amount of time you get with someone, no material item matters," Hill said. "Every moment you get with someone is a moment that [is] blessed, really blessed." #BrainCancer #BrainTumor #BTSM #Caregiving


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Cincinnati meteorologist Rich Apuzzo diagnosed with stage 4 brain cancer - WCPO

Cincinnati meteorologist Rich Apuzzo diagnosed with stage 4 brain cancer - WCPO | Brain Tumors | Scoop.it
Cincinnati meteorologist Rich Apuzzo is weathering the storm of his life.
Pacific Cove's insight:

#BrainTumorThursday - When doctors gave him an estimated number of days he had left to live, he said it didn’t scare him.

Instead of cowering in fear, he said he decided to fight and seek aggressive treatments. #BrainCancer #BrainTumor #BTSM 

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Jack's Angels Foundation | Awareness, Support and Research for DIPG

Jack's Angels Foundation | Awareness, Support and Research for DIPG | Brain Tumors | Scoop.it

On Sunday, February 22, 2015, (2/22/2015) at 12pm, the first DIPG Awareness Run will begin across the Santa Clarita Valley.  The Run starts at the entrance to Six Flags Magic Mountain, at the Old Road and Magic Mountain Parkway and the entrance to Interstate 5, proceeds south to Valencia Blvd., and then goes east past the College of the Canyons and City Hall.  The run stays on this trajectory while Valencia Blvd. becomes Soledad Canyon Rd., and continues until reaching the Von’s shopping center at Sand Canyon Rd—and the entrance to the 14 freeway.

Pacific Cove's insight:

#BrainTumorThursday  - #BrainCancerAwareness -  @JacksAngels1 And as more and more families suffer from DIPG, it won’t be long before the status quo’s unacceptability is too strong in our collective consciousness to ignore.  This is now my personal mission.”   –J. Demeter, Jack’s mom #BrainCancer #BrainTumor #DIPG #BTSM #Caregivers #Caregiving

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Little Rock runner raising money for brain cancer research

Little Rock runner raising money for brain cancer research | Brain Tumors | Scoop.it
For the past three months, a Little Rock couple has been preparing for today's marathon. In addition to training in the gym and on the road, they've also been raising money for a cause close to their hearts.
Pacific Cove's insight:

#BrainTumorThursday - Jeremy Hinton was diagnosed with brain cancer last April. Since then he's had surgery to remove a tumor and has undergone chemotherapy and radiation, all the while training for the half marathon.  #BrainCancer #BrainTumors #BTSM 

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Friends provide family vacations for Moore man with brain cancer

Friends provide family vacations for Moore man with brain cancer | Brain Tumors | Scoop.it
Friends raised funds to allow a Moore man with terminal brain cancer to go to Disney World and Hawaii with his wife and their son.
Pacific Cove's insight:

#BrainTumorThursday - Schneberger, 35, said he always knew what things were truly important — his wife, Susan, their 4-year-old son Blake, family, friends and church — but the disease highlighted how precious every second with them was.  #Alzheimer's #Dementia  #Caregivers #Caregiving  #Seniors #SeniorCare

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Brain cancer survior, UW-Madison student celebrates huge milestone - 620 WTMJ - Milwaukee's Source for Local News and Weather

Brain cancer survior, UW-Madison student celebrates huge milestone - 620 WTMJ - Milwaukee's Source for Local News and Weather | Brain Tumors | Scoop.it
Sunday marked a huge milestone for a University of Wisconsin student. Two years ago she underwent surgery for a potentially deadly brain cancer.
Pacific Cove's insight:

#BrainTumorThursday - While there is no evidence of an active tumor now, Stewart will have to undergo scans for the rest of her life.

She said she wants to the help others now, agreeing to participate in a study on recurring tumors. #BrainCancer #BrainTumor #BTSM 

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I know I’m probably going to die of a brain tumor

I know I’m probably going to die of a brain tumor | Brain Tumors | Scoop.it
But a physician says experimental therapies may at least delay the worst, possibly for years.
Pacific Cove's insight:

#BrainTumorThursday - My medical career ended the day I was diagnosed with a glioma brain tumor, back in 2008. While it was surgically removed several days later, the cancerous growth had already seeded my brain with microscopic deposits, which will help it to return as an angrier and more aggressive glioblastoma.  #BrainCancer #BrainTumor #BTSM 

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Fundraiser started for Allen Park kindergartener diagnosed with rare brain tumor - Southgate News Herald

Fundraiser started for Allen Park kindergartener diagnosed with rare brain tumor - Southgate News Herald | Brain Tumors | Scoop.it
Fundraiser started for Allen Park kindergartener diagnosed with rare brain tumor - Allen Park kindergartener Tristan Molina is a lot like many other 5-year-old boys; he loves to play hockey, enjoys watching and reading about his favorite super...
Pacific Cove's insight:

#BrainTumorThursday - Two days later, Tristan underwent a 20-hour surgery, during which the surgeons were able to remove 90 percent of the tumor. The remaining 10 percent was attached to the nerves in his brain, a factor that made Tristan’s type of brain tumor very rare and more difficult to remove, resulting in the doctor’s recommendation that Tristan go through chemotherapy  #BrainCancer #BrainTumor #BTSM  #Caregiving

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Community rallies for local mom with brain tumor; daughter with rare disease

Community rallies for local mom with brain tumor; daughter with rare disease | Brain Tumors | Scoop.it
A mother battling a brain tumor refuses to have surgery until her 1-year-old with a rare disease gets help.On Friday a charity bowling benefit had the community rallying for Twenty-month-old Zofia ...
Pacific Cove's insight:

#BrainTumorThursday - Zofia's mother Maria has multiple sclerosis, a neurological disease and a brain tumor. Maria has postponed her surgery twice because she can't leave her baby's side.  #BrainCancer

#BrainTumor #BTSM #Caregiving

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Brain Tumor Survivor Spotligh Glynnda Johnson's Glioblastoma Story

Brain Tumor Survivor Spotligh Glynnda Johnson's Glioblastoma Story | Brain Tumors | Scoop.it

After being diagnosed, Johnson underwent a craniotomy where the Glioblastoma was completely removed.  Afterward she went through a round of chemotherapy to make sure it was gone.  Amazingly, the tumor has not returned over 10 years later.  

Pacific Cove's insight:

#BrainTumorThursday - Johnson was diagnosed with a Glioblastoma the size of a racquetball growing behind her eye in April of 2004. Her husband, Henry, thought she was having a stroke and took her to Saint Anthony's.  #BrainCancer #BrainTumor #BTSM #Caregiving

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Toddler with brain tumour given second chance thanks to children's cancer charity

Toddler with brain tumour given second chance thanks to children's cancer charity | Brain Tumors | Scoop.it
A two-year-old girl diagnosed with a rare brain tumour has been given a second chance thanks to help from a children's cancer charity and donations.
Pacific Cove's insight:

#BrainTumorThursday - Atherine and John Paul Bevan were left trying to find £170,000 for Freya's treatment - when the charity Kids N Cancer got in touch.  #BrainCancer #BrainTumor #BTSM #DIPG #Caregiving

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Former NFLer Adrian Peterson Loses 7-Year-Old Son to Cancer - Eurweb.com

Former NFLer Adrian Peterson Loses 7-Year-Old Son to Cancer - Eurweb.com | Brain Tumors | Scoop.it
*Former NFL Chicago running back, Adrian Peterson wrote a heart-wrenching goodbye to his 7-year-old son, A.J., who he lost to cancer on Facebook. “#Ajsoa
Pacific Cove's insight:

#BrainTumorThursday - Peterson and wife, Angela were told back then A.J. had an inoperable brainstem tumor, or Diffuse Intrinsic Pontine Glioma (DIPG). He was given a five to nine percent survival rate prognosis, according to News One. #BrainCancer #BrainTumor #BTSM #Caregiving #DIPG

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Gordon Supercomputer Advances Fight Against Deadly Brain Cancer

Gordon Supercomputer Advances Fight Against Deadly Brain Cancer | Brain Tumors | Scoop.it
A collaboration between San Diego Supercomputer Center (SDSC), Moores Cancer Center, and Department of Neurosciences at the University of California, San D
Pacific Cove's insight:

#BrainTumorThursday - These are the most important gene modules responsible for cancer growth and proliferation, and understanding how they work is key to the development of new drug therapies. #BrainCancer #BrainTumors #BTSM #Caregiving 

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Lauren Hill: One More Game

ESPN Video: Tom Rinaldi tells the story of Lauren Hill, diagnosed with inoperable brain cancer and expected to live only until December, as she takes the basketball court for Division III Mount St. Joseph.
Pacific Cove's insight:

#BrainTumorThursday -  Lauren Hill, diagnosed with inoperable brain cancer and expected to live only until December... #BrainCancer #BrainTumor #BTSM

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Let There Be, in 2015: An Awareness Day for DIPG!

Let There Be, in 2015:  An Awareness Day for DIPG! | Brain Tumors | Scoop.it

For decades in the darkness of despair, thousands dead, it is time. | We the People: Your Voice in Our Government

Pacific Cove's insight:

Pls RT - #BrainTumorThursday - #DIPGAwareness - @JacksAngels1:  The darkness of this disease has few parallels; please help bring light and hope to those currently fighting! Please help us declare an Awareness Day for DIPG in 2015! @BrainCancer @BrainTumor #BTSM #DIPG #Caregiving #Caregivers

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