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Brain Immune Interactions
How the brain and the immune system 'talk to each other'
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Does the scientific journal have a future?

Does the scientific journal have a future? | Brain Immune Interactions | Scoop.it

This summer, scholars will use the break from teaching to submit manuscripts, review papers and develop new ideas. But even as the major functions of scholarly publishing march on, scholars, publishers and librarians start to ask, “What does the future of the scholarly journal look like?” (...) - by Bonnie Swoger, Blog ' Information Culture', Scientific American, June 18, 2014


Via Julien Hering, PhD
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Julien Hering, PhD's curator insight, July 6, 11:35 AM

Science 2.0, open acces archives of pre-print articles, social media measurement of impact of these article... is there a future for traditional publication pathways ? 

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Short Breastfeeding Duration and Low Birth Weight Linked To High Adulthood CRP Levels: Implications for Cardiovascular Disease Risk

Short Breastfeeding Duration and Low Birth Weight Linked To High Adulthood CRP Levels: Implications for Cardiovascular Disease Risk | Brain Immune Interactions | Scoop.it
Systemic inflammation plays a major pathogenic role in cardiovascular (CV) diseases, insulin resistance, and type 2 diabetes mellitus.
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Crowdfunding For Scientists

Crowdfunding For Scientists | Brain Immune Interactions | Scoop.it
Started only 5 years ago but thanks to pioneer sites such as Kickstarter and Indiegogo, crowdfunding is now a mainstream.
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Advice From The Youngest Self-Made Female Billionaire in History

Advice From The Youngest Self-Made Female Billionaire in History | Brain Immune Interactions | Scoop.it

I had the opportunity to attend the keynote presentation of Sara Blakely, Founder of Spanx.  In her one-hour talk, Sara highlighted her fascinating journey from launching a start-up with $5000 in savings to becoming the youngest self-made female billionaire in history. Anyone who’s heard Sara’s story knows it’s exhilarating and motivating, but to see her live brings a new dimension to her story.  She’s fresh, exuberant, funny and completely passionate about helping women feel and look their best, and about reforming all of the misguided trends that have kept in women in painful and ill-fitting undergarments over the last 50 years.


Via Vicki Kossoff @ The Learning Factor
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Jeanne Legare's curator insight, March 7, 6:22 AM

I was so inspired this morning when I read this article. That you are a female or male this article is worth the read!

Karen Kerski's curator insight, March 8, 6:49 AM

The blessing of being a US citizen...create your success. I work with a lot of start-ups and entrepreneurs. The difference between those who succeed and those that don't is fear and no funding. Overcome fear by finding experts you can rely on and spend wisely. Many fail because they cheap out - DIY website, won't spend to get the best package, website and marketing that will get success faster.

Carolyn Williams's curator insight, March 9, 4:28 AM

Body Language :-)

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Neuroendocrine Immunoregulation in Multiple Sclerosis

Neuroendocrine Immunoregulation in Multiple Sclerosis | Brain Immune Interactions | Scoop.it
... system [5]. In summary, the neuroendocrine and immune systems communicate bidirectionally via shared receptors and shared messenger molecules, variously called hormones, neurotransmitters, or cytokines.
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9th ISNIM Congress 2014 - congress announcement | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

9th ISNIM Congress 2014 - congress announcement | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it
An invitation and meeting announcement about the next International Society for NeuroImmunoModulation (ISNIM) congress in Liege, Belgium, Sept 2014
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Sleep 'cleans' the brain of toxins

Sleep 'cleans' the brain of toxins | Brain Immune Interactions | Scoop.it
The brain uses sleep to wash away the waste toxins of a hard day's thinking, US researchers have demonstrated.

Via Romylos Pantzakis
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Fibromyalgia: Dr. Frank Rice the person helping those that sufferers - Washington Times

Fibromyalgia: Dr. Frank Rice the person helping those that sufferers - Washington Times | Brain Immune Interactions | Scoop.it
Fibromyalgia: Dr. Frank Rice the person helping those that sufferers
Washington Times
Dr.
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Why We Keep Getting the Same Old Ideas

Why We Keep Getting the Same Old Ideas | Brain Immune Interactions | Scoop.it

"Aoccdrnig to a rscheearch at Cmabridge Uinvervtisy, it deosnt mttaer in waht oredr the litteers in a wrod are, the olny iprmoetnt tihng is taht the frist and lsat ltteer be at the rghit pclae. The rset can be a ttoal mses and you can sitll raed it wouthit a porbelm. Tihs is besauae ocne we laren how to raed we bgien to aargnre the lteerts in our mnid to see waht we epxcet tp see. The huamn mnid deos not raed ervey lteter by istlef, but the wrod as a wlohe. We do tihs ucnsolniuscoy. (....)


"When information enters the mind, it self-organizes into patterns and ruts much like the hot water on butter. New information automatically flows into the preformed grooves. After a while, the channels become so deep it takes only a bit of information to activate an entire channel. This is the pattern recognition and pattern completion process of the brain. Even if much of the information is out of the channel, the pattern will be activated. The mind automatically corrects and completes the information to select and activate a pattern.This is why you can read the jumbled letters above as words.

 

This is also why when we sit down and try to will new ideas or solutions; we tend to keep coming up with the same-old, same-old ideas. Information is flowing down the same ruts and grooves making the same-old connections producing the same old ideas over and over again. Even tiny bits of information are enough to activate the same patterns over and over again. (...)

 

How then can we change our thinking patterns? Think again about the dish of butter with all the preformed channels. Creativity occurs when we tilt the dish in a different direction and force the water (information) to create new channels and make new connections with other channels. These new connections give you different ways to focus your attention and different ways to interpret whatever you are focusing on. Nature gets variation with genetic mutations. Creative thinkers get variation by conceptually combining dissimilar subjects which changes our thinking patterns and provides us with a variety of alternatives and conjectures. (...)"


Via Amira
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dephunked's comment, September 26, 2012 6:47 AM
Wlidcat,

...I´ve thought about how creative thinkers have been discriminated throughout modern civilization...

...as novelty naturally falls outside the norm, and modern civilization has been inherently, systematically norm-biased, I have this feeling that non-successful creatives have been subjected to significant social and systematic discrimination...

...top down bureaucratic organization shaped the social norm to disclude creativity, novelty thinking, and social evolution, the majority of those innately prone to innovation could count on little help and reward from the norm-biased surroundings... their life was a life of struggle...

...It´s unnatural for a creative neurotype to conform to the norm, the evolutionary origin and purpose of creativity is cultural evolution. Creativity evolves the norm, it cannot fit into it, and within the creative thinkers, the creative drive is stronger then the drive to conform...

...during my brief medical practice amongst those at the bottom of civilization, the homeless, I saw so much misunderstood potential, so much creativity and ingenuity and empathy, and so little recognition from their "society". Systematically discouraged and misunderstood, forced into poverty and stigma-generated alienation...

...in every one of them, I saw myself...


These social patterns are typical for many shortcomings of top-down bureaucracy, but I have a feeling that creative thinkers in particular have suffered from the hegemonic-ish norm. I haven´t found much literature about it, and I believe it´s important for society to acknowledge this, just as important as the pride movement to end and avow the discrimination of homosexuality. Important at least, as a reminder of the darker angels of our past.

...what do you think?
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Neuroscience thinks big (and collaboratively)

espite cash-strapped times for research, several ambitious collaborative neuroscience projects have attracted large amounts of funding and media attention. In Europe, the Human Brain Project aims to develop a large-scale computer simulation of the brain, whereas in the United States, the Brain Activity Map is working towards establishing a functional connectome of the entire brain, and the Allen Institute for Brain Science has embarked upon a 10-year project to understand the mouse visual cortex (the MindScope project). US President Barack Obama's announcement of the BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies Initiative) in April 2013 highlights the political commitment to neuroscience and is expected to further foster interdisciplinary collaborations, accelerate the development of new technologies and thus fuel much needed medical advances. In this Viewpoint article, five prominent neuroscientists explain the aims of the projects and how they are addressing some of the questions (and criticisms) that have arisen. - by Kandel ER et al., Nature Reviews Neuroscience 14, 659–664 (2013) 


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Interferon and the Central Nervous System | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Interferon and the Central Nervous System | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it
Interferons (IFNs) are glycoproteins known as cytokines. These cytokines got their name by Isaacs and Lindenmann after their ability to interfere with viral
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ATP as a Neuromediator at the Brain-Immune Interface | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

ATP as a Neuromediator at the Brain-Immune Interface | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it

It has now also become clear that ATP-mediated signaling is not restricted within the border of the nervous system. Purinergic receptors are expressed in essentially all cells and tissues, including the cells of the immune system. Therefore, ATP is now regarded as a universal signaling substance, rather than a pure neurotransmitter or neuromodulator, playing a major role in the cross talk between different cell types, and at the interface between the nervous system and the immune system.

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Thymus Emergence & Evolution of Immune and Neuroendocrine Systems | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Thymus Emergence & Evolution of Immune and Neuroendocrine Systems | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it
Galen (129 – 210 or 216 AD) first described an organ located behind the sternum and named it ‘thymus’ because of its close resemblance with a leaf of the
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A Set of 10 Lipid Biomarkers May Predict Alzheimer’s and Mild Dementia

A Set of 10 Lipid Biomarkers May Predict Alzheimer’s and Mild Dementia | Brain Immune Interactions | Scoop.it
In the last 15 years there have been over 100 attempts to develop a treatment for Alzheimer’s disease (AD), but all have failed.
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Perispinal Etanercept Improves Neurological Function in Chronic Brain Injury

Perispinal Etanercept Improves Neurological Function in Chronic Brain Injury | Brain Immune Interactions | Scoop.it
A new case report by Tobinick et al. in the May 2014 issue of Clinical Drug Investigation describes striking success with a single perispinal etanercept dose in a patient who sustained brain injury 3 years prior.
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The 2nd International Meeting on Nerve-Driven Immunity | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

The 2nd International Meeting on Nerve-Driven Immunity | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it
News and announcement about the meeting that will take place at the Nobel Forum, Karolinska Institutet, Solna, Stockholm, August 20-21, 2014.
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PLOS ONE: Exercise Training Attenuates Hypertension and Cardiac Hypertrophy by Modulating Neurotransmitters and Cytokines in Hypothalamic Paraventricular Nucleus

PLOS ONE: Exercise Training Attenuates Hypertension and Cardiac Hypertrophy by Modulating Neurotransmitters and Cytokines in Hypothalamic Paraventricular Nucleus | Brain Immune Interactions | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Link between gut and brain suggests therapies for autism

Link between gut and brain suggests therapies for autism | Brain Immune Interactions | Scoop.it
Probiotics can alleviate the symptoms of autism-like disorders in mice, according to a US study published today in the journal…

Via David Holloway
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Nobel winner declares boycott of top science journals

Nobel winner declares boycott of top science journals | Brain Immune Interactions | Scoop.it
Randy Schekman says his lab will no longer send papers to Nature, Cell and Science as they distort scientific process

Via HealthRx Corporation
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Aspartame Damages The Brain At Any Dose | Alternative

Aspartame Damages The Brain At Any Dose | Alternative | Brain Immune Interactions | Scoop.it
Did you know that Aspartame has been proven to cause brain damage by leaving traces of Methanol in the blood? It makes you wonder why Aspartame has been approved as “safe” and is found in thousands of food products.
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Neuroscience and Creativity

Neuroscience and Creativity | Brain Immune Interactions | Scoop.it
Susan Greenfield is a scientist best known for her research on neurodegenerative disorders and her efforts to popularize understanding of brain mechanisms through public appearances and writings.
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'News is to the mind what sugar is to the body'. Towards a Healthy News Diet by Rolf Dobelli

'News is to the mind what sugar is to the body'. Towards a Healthy News Diet by Rolf Dobelli | Brain Immune Interactions | Scoop.it
Rolf Fobelli: News is to the mind what sugar is to the body
“ “We humans seem to be natural-born signal hunters, we’re terrible at regulating our intake of information. We’ll consume a ton of noise if...

Via Amira
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Amira's curator insight, March 2, 2013 4:45 PM

"Afraid you will miss “something important”? From my experience, if something really important happens, you will hear about it, even if you live in a cocoon that protects you from the news. Friends and colleagues will tell you about relevant events far more reliably than any news organization. They will fill you in with the added benefit of meta-information, since they know your priorities and you know how they think. You will learn far more about really important events and societal shifts by reading about them in specialized journals, in-depth magazines or good books and by talking to the people who know. (…)

The more “news factoids” you digest, the less of the big picture you will understand. (…)

Thinking requires concentration. Concentration requires uninterrupted time. News items are like free-floating radicals that interfere with clear thinking. News pieces are specifically engineered to interrupt you. They are like viruses that steal attention for their own purposes. (…) [F]ewer than 10% of the news stories are original. Less than 1% are truly investigative. And only once every 50 years do journalists uncover a Watergate.  (...) The copying and the copying of the copies multiply the flaws in the stories and their irrelevance."

“When people struggle to describe the state that the Internet puts them in they arrive at a remarkably familiar picture of disassociation and fragmentation. Life was once whole, continuous, stable; now it is fragmented, multi-part, shimmering around us, unstable and impossible to fix. The world becomes Keats’s “waking dream,” as the writer Kevin Kelly puts it.” — Adam Gopnik

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Are you a thought leader?

Are you a thought leader? | Brain Immune Interactions | Scoop.it
Ask.com says that a thought leader is an individual or firm that is recognized as an authority in a specialized field and whose expertise is sought and often rewarded.
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T Cell and Antigen Presenting Cell Activity During Sleep | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

T Cell and Antigen Presenting Cell Activity During Sleep | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it

Sleep regulates immune functions. The finding that sleep and specifically SWS has immuno-supporting effects on Th1 immune responses has broad immunological and clinical implications. It offers the opportunity to optimize vaccination strategies, the use of endogenous adjuvants  and it likely explains immunodeficiency and Th2 shifts that are observed with sleep loss due to insomnia, depression or alcoholism. In addition, the sleep-associated changes in hormones and cytokine production may help to elucidate the mechanisms contributing to the early morning peak of disease symptoms such as joint pain and stiffness in rheumatoid arthritis and to improve the timing of anti-inflammatory drug therapy

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Mainstream Immunology Research and Cultural Separation | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Mainstream Immunology Research and Cultural Separation | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Brain Immune Interactions | Scoop.it
One of the curious aspects of modern biomedicine is the “cultural separation” of immunology research from neurobiology and physiology research. One can
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