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Biotechnology Entrepreneurship Education
This collection of articles, publications and resources is curated to support the CSUPERB's Early-stage Biotechnology Commercialization Challenge and the CSU I-Corps, as well as other knowledge- and technology-transfer efforts across the California State University.
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7 Ways Universities Are (Finally) Getting With the Entrepreneurship Program

7 Ways Universities Are (Finally) Getting With the Entrepreneurship Program | Biotechnology Entrepreneurship Education | Scoop.it
In a race for relevance, universities up the entrepreneurial ante.
Susan M. Baxter's insight:

Nice summary of the entrepreneurial education needed on campuses today (students, faculty and administrators!)!

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I-Corps @ NIH – Pivoting the Curriculum

I-Corps @ NIH – Pivoting the Curriculum | Biotechnology Entrepreneurship Education | Scoop.it
We’ve pivoted our Lean LaunchPad / I-Corps curriculum. We’re changing the order in which we teach the business model canvas and customer development to better-fit therapeutics, diagnostics and medi...
Susan M. Baxter's insight:

After testing out the I-Corps curriculum during Fall 2013, Steve Blank's team learned some tweaks were needed for the life sciences.  The teaching team ran into the usual "buzz saw" of customer definition, IP and regulatory environment that foils many biotech/life science teams - nascent, novice and serial entrepreneurs alike!

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From Lab Bench to Innovation: Critical Challenges to Nascent Academic Entrepreneurs by Roman Lubynsky :: SSRN

From Lab Bench to Innovation: Critical Challenges to Nascent Academic Entrepreneurs by Roman Lubynsky :: SSRN | Biotechnology Entrepreneurship Education | Scoop.it
University research laboratories are important sources of the inventions and discoveries that become significant innovations with broad economic and societal im
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In my opinion this important 2013 paper makes key and insightful points about academic research-based innovation.  The report is based on a dissertataion by Lubynsky, who works with MIT's venture mentoring service.  A must-read for any academic administrator or policy maker involved with biotechnology entrepreneurship and technology transfer.

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Open Innovation Handbook for Researchers

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Holmberg, Norrman & Theander (Innovations-Kontor Vast, Sweden) have done a wonderful service for the academic research community. This 2013 handbook defines evolving terms used in the open innovation community (follow along at http://www.openinnovation.net/). Wonderful resource with many "clickable" links embedded.

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Leaning Out the Life Sciences: Interview with Steve Blank

Leaning Out the Life Sciences: Interview with Steve Blank | Biotechnology Entrepreneurship Education | Scoop.it
Steve Blank, ©Eric Millette If you are an entrepreneur, you probably already know who Steve Blank is. If you want to be an entrepreneur, you definitely
Susan M. Baxter's insight:

A great look back by Medgadget at Steve Blank's experience working with academic,  "nascent," life sciences  entrepreneurs. It also provides a really nice background on why biotechnology entrepreneurship might be different - but also the same as other sectors. These are lessons we've learned via the CSUPERB-I2P early-stage biotech commercialization challenge, as well!

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Why A Startup Is Not A Big Company

Why A Startup Is Not A Big Company
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Kaufmann Foundation sponsors a series featuring Steve Blank and his ideas about the fundamental differences between a start-up company and an established one.   Important distinction to make and especially important for academic researchers deciding what kind of university-industry partnerships might be interesting or useful. 

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Lesson Learned in Medical Devices

Lesson Learned in Medical Devices | Biotechnology Entrepreneurship Education | Scoop.it
This post is part of our series on the National Science Foundation I-Corps Lean LaunchPad class in Life Science and Health Care at UCSF.
Susan M. Baxter's insight:

This is a terrifically helpful post from the NSF-funded Lean LaunchPad class at UCSF.  Compared to other posts on the class, the 'lessons learned' in this blog entry from Steve Blank is the most representative of academic biotechnology commercialization in my experience.  The learning arc the KNOX team experiences is very similar to the experiences of three years of CSUPERB-I2P Challenge Teams we've worked with as well.  I call it the "buzzsaw" of biotech customer definition - it can be daunting to even the most experienced venture capitalists as well as student entrepreneurs!  I recommend you watch BOTH the videos embedded in the blog post if you're interested in mentoring or forming a bioengineering/medical device-oriented I-Corps team!

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The Ice House Manner and Mindset of Teaching Entrepreneurship

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Nifty sketchbook video (< 3min) from Kauffman Foundation that explains what entrepreneurship really is not....and why entrepreneurship education needs to encourage a mindset (not a set of disciplinary subjects). 

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Finding better ways to negotiate biotech intellectual property

Finding better ways to negotiate biotech intellectual property
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It doesn't supplant real legal advice - but Kauffman reports on Partnering for Cures meeting recommendations on negotiating life science intellectual property.

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Nevermore Sithole's curator insight, February 13, 2014 7:34 AM
Finding better ways to negotiate biotech intellectual property
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The Innovative and Entrepreneurial University Report (NACIE, 2013)

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As part of National Entrepreneurship Month (who knew?!), the Department of Commerce's National Advisory Council on Innovation and Entrepreneurship issued this report on exemplar programs on campuses nationwide. The Council was funded by the America COMPETES Act. Many program examples are described in the report - including service learning opportunities!  Examples tend to map to universities represented by Council members and grantees funded by the Commerce department's i6 program, but many "best practices" to note throughout.  See also The Chronicle's article on the report here: http://chronicle.com/blogs/wiredcampus/universities-foster-entrepreneurship-and-innovation-federal-report-says/48059

 

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Genentech start 'ordinary'

Genentech start 'ordinary' | Biotechnology Entrepreneurship Education | Scoop.it
Academics debated the fallout of Herb Boyer and Stan Cohen patenting research from...
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A little bit of history behind the commercialization effort that led to Genentech...and the academic controversy that accompanied the effort.

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Entrepreneurship Education Comes of Age on Campus

Entrepreneurship Education Comes of Age on Campus | Biotechnology Entrepreneurship Education | Scoop.it
The first paper "Entrepreneurship Education Comes of Age on Campus" is a qualitative report on a gathering of educators from 16 institutions with notable entrepreneurship education programs — including some who participated in the Kauffman Campuses...
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A new essay (August 2013) outlining high level cultural changes and projects to increase entrepreneurship focus across college campuses.  Essay is a report out on two rounds of the Kauffman Foundation's Kauffman Campus Initiative.

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Ten Tips for Raising Startup Capital in Biotech

Ten Tips for Raising Startup Capital in Biotech | Biotechnology Entrepreneurship Education | Scoop.it
Summer is gone and the hectic autumn schedule is upon us (despite hitting 96F in Boston on Wednesday): back to the routine of board meetings, SABs, conferences, diligence sessions, and a ramped up travel schedule.
Susan M. Baxter's insight:

Bruce Booth's blog has "unmasked" some of the mysteries behind finding venture capital (VC) for biopharmaceutical startups.  He's a practicing life science VC so his advice is relevant to companies trying to raise capital right now. His advice may not be applicable to all biotechnology entrepreneurs - especially those not ready for VC pitches - but is informative for all.

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Getting Real: The Latest In University-Business Partnerships

Getting Real: The Latest In University-Business Partnerships | Biotechnology Entrepreneurship Education | Scoop.it
An in-depth report on the next generation of university-business partnerships reveals several interesting trends for training a highly-skilled workforce.
Susan M. Baxter's insight:

This article starts off skating the surface of university-industry partnerships - but in the end it provides a comprehensive, up-to-the-minute view of what works and why.  Recommended read!

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NIH Looking to Kick-Start Biotech Startups

NIH Looking to Kick-Start Biotech Startups | Biotechnology Entrepreneurship Education | Scoop.it
Agency will offer I-Corps entrepreneurship boot camps
Susan M. Baxter's insight:

A very accurate and realistic view of the I-Corps program.  It isn't all about new company formation (in fact many of us think too many bioscience researchers start companies way too early merely to qualify for SBIR funding and gain additional research funding). It is important to recognize efficiency in commercialization is important - especially in the life sciences where clinical trials drive up product development costs quickly.  One way to improve commercialization efficiency is with entrepreneurship education.

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Get the Heck Out of the Building in Founder's School: Part 2

Get the Heck Out of the Building in Founder's School: Part 2 | Biotechnology Entrepreneurship Education | Scoop.it
With a ~$2 billion endowment the Kauffman Foundation is the largest non-profit focused on entrepreneurship in the world. Giving away $80 million to every year (~$25 million to entrepreneurial cause...
Susan M. Baxter's insight:

Great set of videos from Steve Blank and the Kauffman Foundation.  The series of modules addresses customer discovery and definition - the step most nascent academic entrepreneurs (especially in the life sciences) avoid until the last possible (and often too late) moment.   The videos should be of interest to entrepreneurship educators, I-Corps teams and, yes, nascent academic entrepreneurs!

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2014 Talent Integration: California Workforce Trends in the Life Science Industry

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BIOCOM Institute, BayBio Institute, the East Bay Biomedical Manufacturing Network, and the California Community Colleges combined resources to publish this biotechnology workforce trends report.  A must-read for any scientist, engineer or entrepreneur thinking about working in this industry.

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Lean LaunchPad Educators' Teaching Handbook

Susan M. Baxter's insight:

NCIIA has done a nice service by publishing this handbook (January 2013).  It does a great job introducing the Business Model Canvas as a weekly tracking tool for product concept development.

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It’s Time to Play Moneyball: The Investment Readiness Level

It’s Time to Play Moneyball: The Investment Readiness Level | Biotechnology Entrepreneurship Education | Scoop.it
Investors sitting through Incubator or Accelerator demo days have three metrics to judge fledgling startups – 1) great looking product demos, 2) compelling PowerPoint slides, and 3) a world-class t...
Susan M. Baxter's insight:

Steve Blank is adopting an "investment readiness" scale to grade product concepts based on academic discoveries and research. I think it's a pragmatic way to demonstrate the gap between typical work done in an NIH-funded setting to work with commercialization potential.  While it's not fool-proof or hype-proof - I do think it's a nice framing device to use when talking to PIs about technology commercialization. 

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Don’t Underestimate the Undergraduates

Don’t Underestimate the Undergraduates | Biotechnology Entrepreneurship Education | Scoop.it
Jim Hornthal splits his time between venture capital, entrepreneurship and education. Jim has founded six companies, including Preview Travel, one of the first online travel agencies, which went pu...
Susan M. Baxter's insight:

Jim Hornthal (Princeton) reviews his Topics in Entrepreneurship course using Steve Blank's "lessons learned" format.  Many of Hornthal's findings echo CSUPERB's experience with the Biotechnology Early-Stage Commercialization Challenge - the undergraduates are equally capable as the graduate students!  One theory that keeps cropping up is that undergrads are more likely to listen and learn from industry experts and potential customers than graduate students/postdoc/faculty researchers who are wedded to their science/ideas/technology.  Coach-ability is a wonderful trait for all entrepreneurs at any and all levels!

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Lean LaunchPad for Life Sciences - Value Proposition and Customers

Lean LaunchPad for Life Sciences - Value Proposition and Customers | Biotechnology Entrepreneurship Education | Scoop.it
We’re deep into teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) at UCSF with a team of veteran venture capitalists. (The cl...
Susan M. Baxter's insight:

NSF funded Steve Blank and UCSF to explore the application of Lean LaunchPad ideas to life science commercialization. This blog entry describes the broad and very different customer segments underneath the life science industry umbrella.  This is probably the number one lesson of the CSUPERB-I2P early-stage biotech commercialization challenge - hopefully Blank's videos and vignettes will move teams past this conceptual barrier earlier!

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How to Tissue-Engineer a Startup

How to Tissue-Engineer a Startup | Biotechnology Entrepreneurship Education | Scoop.it
How is working with stem cells like founding a startup? One entrepreneur who has done both explains.  By Ivana Gadjanski (Co-founder & Chief Science Officer, Pubsonic) I’m a stem cell scientist. I’m an entrepreneur.
Susan M. Baxter's insight:

Women 2.0 is an "online magazine" for aspirational women entrepreneurs.  This story features a stem cell researcher/entrepreneur and gives voice to "how it's done" - that is - at least one researcher's opinion!

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Beyond Metropolitan Startup Rates: Regional Factors Associated with Startup Growth

Beyond Metropolitan Startup Rates: Regional Factors Associated with Startup Growth | Biotechnology Entrepreneurship Education | Scoop.it
The paper, "Beyond Metropolitan Startup Rates: Regional Factors Associated with Startup Growth," reports on entrepreneurship activity in 356 U.S. metros.
Susan M. Baxter's insight:

This 2014 report sponsored by the Kauffman Foundation correlates college graduation rates with startup rates.  They suggest "policymakers best can influence entrepreneurship by finding ways to effectively connect these two factors."

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Contagious Entrepreneurship: People Who Know Entrepreneurs Are More Likely to Become Entrepreneurs

Contagious Entrepreneurship: People Who Know Entrepreneurs Are More Likely to Become Entrepreneurs | Biotechnology Entrepreneurship Education | Scoop.it
The new paper "Getting the Bug: Is (Growth) Entrepreneurship Contagious?
Susan M. Baxter's insight:

This is a nifty survey sponsored by the Kauffman Foundation showing the "viral transmission" of entrepreneurship through - yet again - networks.  The survey data shows especially the need for exposure to "growth" entrepreneurship (think biotech); currently those networks skew toward male & upper income practitioners. A nice justification for programs like the CSUPERB Early-stage Biotechnology Commercialization Challenge, the CSU I-Corps and other programs that bring together biotech practitioners with "nascent academic entrepreneurs."

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Centro de Innovación Educativa's curator insight, April 8, 2014 1:13 PM

¡Rodéate de gente emprendedora! Es contagioso

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This Will Save Us Years – Lean LaunchPad for Life Science

This Will Save Us Years – Lean LaunchPad for Life Science | Biotechnology Entrepreneurship Education | Scoop.it
We’re deep into week 2 of teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) this October at UCSF with a team of veteran venture capitalists.
Susan M. Baxter's insight:

Steve Blank posts a < 2 min. video demonstrating why emerging academic entrepreneurs need to talk with customers now...not "later!"

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