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Biosciencia News
Everyday news through scientist eyes.
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A Tumor With A Sweet Tooth: Innovative MRI Technique Uses Sugar To Track Cancer

A Tumor With A Sweet Tooth: Innovative MRI Technique Uses Sugar To Track Cancer | Biosciencia News | Scoop.it
Scientists at University College London use sugar to make cancer light up on magnetic resonance imaging (MRI) scanners.
Biosciencia's insight:

"We can detect cancer using the same sugar content found in half a standard sized chocolate bar," said senior author Professor Mark Lythgoe, the Director of Centre for Advanced Biomedical Imaging at University College London. His team's work was published today in Nature Medicine.

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Whole human brain mapped in 3D

Whole human brain mapped in 3D | Biosciencia News | Scoop.it
Ten-year 'BigBrain' effort yields 10-trillion-byte atlas of fine-scale cerebral anatomy.
Biosciencia's insight:

Researchers used a special tool called a microtome cut a human brain preserved in paraffin wax into 20-micrometre thick slivers and map its anatomical structure with high resolution.

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Antibody wakes up T-cells to make cancer vanish

Antibody wakes up T-cells to make cancer vanish | Biosciencia News | Scoop.it
New antibody treatment halts the most deadly form of skin cancer in its tracks by prodding the immune system into action    
Biosciencia's insight:

Tumours in several people with an advanced form of skin cancer have completely disappeared after treatment with one of three drugs that force tumour cells out of hiding. The patient's own immune system can then recognise the cancer and destroy it.

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3-D printed windpipe gives infant breath of life

3-D printed windpipe gives infant breath of life | Biosciencia News | Scoop.it
A flexible, absorbable tube helps a baby boy breathe, and heralds a future of body parts printed on command.
Nature News doi: 10.1038/nature.2013.13085
Biosciencia's insight:

The trachea, or windpipe, is essentially constructed much like a vacuum cleaner hose, says Glenn Green, an ear nose and throat specialist (otolaryngologist) at the University of Michigan, who helped to develop the device.

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Stem-cell treatment restores sight to blind man

Stem-cell treatment restores sight to blind man | Biosciencia News | Scoop.it
A man blinded by the degeneration of his retinal cells can see well enough to get a driver's licence after receiving a stem-cell transplant    
Biosciencia's insight:

Age-related macular degeneration can leave people with only peripheral vision.

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Human stem cells created by cloning

Human stem cells created by cloning | Biosciencia News | Scoop.it
Breakthrough sets up showdown with induced adult lines.
Biosciencia's insight:

A paper published this week by Shoukhrat Mitalipov, a reproductive biology specialist at the Oregon Health and Science University in Beaverton, and his colleagues is sure to rekindle that debate. Mitalipov and his team have finally created patient-specific ESCs through cloning, and they are keen to prove that the technology is worth pursuing.

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New memories filmed in action for first time

New memories filmed in action for first time | Biosciencia News | Scoop.it
The processes of memory formation and retrieval have been observed across the entire brain for the first time using transparent zebrafish    
Biosciencia's insight:

Got a memory like a fish? The first study to visualise live memory retrieval in the whole brain has not only debunked the "three-second memory" myth, but also sheds light on the brain processes involved in forming long-term memories.

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New forensic technique for estimating time of death by checking internal clock of the human brain

New forensic technique for estimating time of death by checking internal clock of the human brain | Biosciencia News | Scoop.it
People with severe depression have a disrupted “biological clock” that makes it seem as if they are living in a different time zone to the rest of the healthy population living alongside them, a study has found.
Biosciencia's insight:

The researchers found that they could estimate a healthy person's time of death to within a few hours by analysing the activity levels of a set of genes.

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Bioengineered kidney makes urine

Regeneration and experimental orthotopic transplantation of a bioengineered kidney

http://www.nature.com/nm/journal/v19/n5/abs/nm.3154.html

Biosciencia's insight:

Scientists at the Massachusetts General Hospital in Boston have created a bioengineered kidney that can be transplanted back into a rat, where it begins making urine. Nature Medicine takes a look at how growing organs in the laboratory might someday be the solution to help people with end-organ failure.

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Lists of cancer mutations awash with false positives

Lists of cancer mutations awash with false positives | Biosciencia News | Scoop.it
But researchers show artefacts can be reduced by taking differing rates of mutation into account.
Biosciencia's insight:

Tumour cells, such as these from a lung cancer, are riddled with genetic mutations, but many of those are caused by the cancer rather than being involved in causing the disease.

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A step closer to artificial livers

A step closer to artificial livers | Biosciencia News | Scoop.it
Prometheus, the mythological figure who stole fire from the gods, was punished for this theft by being bound to a rock. Each day, an eagle swept down and fed on his liver, which then grew back to be eaten again the next day.
Biosciencia's insight:

MIT researchers have generated mature liver cells from induced pluripotent stem cells. In this image, the cell nuclei are stained blue. The green stain identifies liver cells, and the red stain identifies cells that are actively dividing.

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Genetic Scientists Eliminate Schizophrenia Symptoms in Mice

Genetic Scientists Eliminate Schizophrenia Symptoms in Mice | Biosciencia News | Scoop.it
A multinational group of geneticists writing in the journal Neuron has reversed schizophrenia-like symptoms in adult mice by restoring normal expression to a gene called Neuregulin-1 (NRG1 for short).
Biosciencia's insight:

Roles of Neuregulin 1 in neural development. NRG1 is released from neurons to promote the formation and maintenance of radial glial cells. Tangential migration of γ-aminobutyric acid-ergic interneurons requires NRG1 in the cortical region. Myelination and ensheathment of peripheral nerves are controlled by the amounts of NRG1 produced in substrate axons. NRG1 from axons might regulate oligodendrocyte development and myelination of axons in the CNS. NRG1 is also necessary for the formation of neuromuscular junctions

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Genetically Modified T Cell Therapy Shown to be Safe, Lasting in Decade-Long Penn Medicine Study of HIV Patients

Genetically Modified T Cell Therapy Shown to be Safe, Lasting in Decade-Long Penn Medicine Study of HIV Patients | Biosciencia News | Scoop.it
HIV patients treated with genetically modified T cells remain healthy up to 11 years after initial therapy, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the new issue of Science Translational Medicine.
Biosciencia's insight:

"We have 43 patients and they are all healthy," says senior authorCarl June, MD, a professor of Pathology and Laboratory Medicine at Penn Medicine. "And out of those, 41 patients show long term persistence of the modified T cells in their bodies."

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Shocks to the brain improve mathematical abilities

Shocks to the brain improve mathematical abilities | Biosciencia News | Scoop.it
Benefits of electrical brain stimulation lasted months but critics point to study's small size as a weakness.
Biosciencia's insight:

A gentle electrical stimulation to the brain improved university students' abilities at performing simple arithmetic calculations.

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News Centre - Fighting cancer

News Centre - Fighting cancer | Biosciencia News | Scoop.it
The Immunocore team engineered a range of TCRs to bind very tightly to cancer cells and equipped them with the ability to activate non-cancer specific T cells.
Biosciencia's insight:

Published in Nature Medicine, the study examined the potential of molecules on the surface of anti-cancer killer T cells, known as T cell receptors (TCRs) to be used to treat cancers for which few disease-specific targets are available.

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Nobel Prize Rockets Stem Cell Program to New Heights

Nobel Prize Rockets Stem Cell Program to New Heights | Biosciencia News | Scoop.it
Shinya Yamanaka's Nobel Prize for stem cell research brought fresh attention to something UCSF long ago sensed and seized: the promise of regeneration medicine for repairing or replacing damaged cells, tissues, and even whole organs.
Biosciencia's insight:

Gladstone scientists took skin cells from a patient with a heart disease and reprogrammed them into something known as iPS cells, which act very much like embryonic stem cells. In this magnified image, the iPS cells are growing into heart cells (blue) and nerve cells (green).

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