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Scientists Use New Engineered Virus to Restore Sight | Medicine | Sci-News.com

Scientists Use New Engineered Virus to Restore Sight | Medicine | Sci-News.com | Biosciencia News | Scoop.it
Researchers have engineered a new adeno-associated virus that could greatly expand gene therapy to help restore sight to patients with blinding diseases.
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Over the last six years, several teams of scientists have successfully treated people with a rare inherited eye disease by injecting a virus with a normal gene directly into the retina of an eye with a defective gene.

More at : http://www.berkeley.edu/news/media/releases/2006/02/07_virus.shtml

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Reading DNA, backward and forward

Reading DNA, backward and forward | Biosciencia News | Scoop.it
MIT biologists have discovered a mechanism that allows cells to read their own DNA in the correct direction and prevents them from copying most of the so-called “junk DNA” that makes up long stretches of our genome.
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DNA, which is housed within the nucleus of cells, controls cellular activity by coding for the production of RNAs and proteins. To exert this control, the genetic information encoded by DNA must first be copied, or transcribed, into messenger RNA (mRNA).

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Mutant Silkworms Spin Fluorescent Silk in 3 Colors | Wired Science | Wired.com

Mutant Silkworms Spin Fluorescent Silk in 3 Colors | Wired Science | Wired.com | Biosciencia News | Scoop.it
Silkworms in a Japanese lab are busy spinning silks with a colorful glow.
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Malcolm Fraser, a molecular biologist at the University of Notre Dame, suggests that while the fluorescent silks are interesting, they’d be even better, and more practical, if the colors were more robust. In 2011, Fraser and his colleagues engineered a silkworm that spun spider silk. “The coloration conferred by these fluorescent protein sequences is not strong enough to impart a significant coloration in visible light,” he said. “Coloration using dyes is much more versatile in terms of the color palette, and certainly more practical in terms of creating fabrics.

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Enhancing RNA interference

Enhancing RNA interference | Biosciencia News | Scoop.it
Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes.
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Helping RNA escape from cells’ recycling process could make it easier to shut off disease-causing genes. Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes. Although this approach has shown some promise, scientists are still not sure exactly what happens to the nanoparticles once they get inside their target cells.

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The genome's 3D structure shapes how genes are expressed

The genome's 3D structure shapes how genes are expressed | Biosciencia News | Scoop.it
Scientists from Australia and the United States bring new insights to our understanding of the three-dimensional structure of the genome, one of the biggest challenges currently facing the fields of genomics and genetics.
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Dr Tim Mercer and Professor John Mattick from Sydney's Garvan Institute of Medical Research and Professor John Stamatoyannopoulos from Seattle's University of Washington analysed the genome's 3D structure, at high resolution.

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