Research Biotechnologies
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Scooped by Olivier Garnier
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Autophagy in Antarctica: combating dehydration stress in the world's southernmost insect. - PubMed - NCBI

Autophagy. 2013 Apr;9(4):629-31. doi: 10.4161/auto.23643. Epub 2013 Feb 4. Research Support, U.S. Gov't, Non-P.H.S.
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Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis. - PubMed - NCBI

Mech Ageing Dev. 2016 Apr;155:10-21. doi: 10.1016/j.mad.2016.02.003. Epub 2016 Mar 7. Research Support, Non-U.S. Gov't; Review
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Dietary fat and gut microbiota interactions determine diet-induced obesity in mice. - PubMed - NCBI

Mol Metab. 2016 Oct 13;5(12):1162-1174. eCollection 2016.
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Aging | Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in Drosophila - Full Text

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A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet. - PubMed - NCBI

Obesity (Silver Spring). 2016 Nov 22. doi: 10.1002/oby.21706. [Epub ahead of print]
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A novel enzyme with antioxidant capacity produced by the ubiquitous skin colonizer Propionibacterium acnes

The role of the skin microbiota in human health is poorly understood. Here, we identified and characterized a novel antioxidant enzyme produced by the skin microbiota, designated RoxP for radical oxygenase of Propionibacterium acnes.
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Plum polyphenols inhibit colorectal aberrant crypt foci formation in rats: potential role of the miR-143/protein kinase B/mammalian target of rapam... - PubMed - NCBI

Nutr Res. 2016 Oct;36(10):1105-1113. doi: 10.1016/j.nutres.2016.06.008. Epub 2016 Jun 14.
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Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis. - PubMed - NCBI

Epigenetics Chromatin. 2016 Oct 25;9:45. eCollection 2016.
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Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice

Nutrition is important during development. This appears to be true even in utero, with potential long-lasting effects on adult phenotype and disease. Epigenetic factors are prime suspects in identifying the corresponding molecular mechanism because they can be maintained throughout cell division. Holland et al. show in mice that in utero nutritional deficits influence offspring growth through epigenetic states at multicopy ribosomal DNA elements. This effect is influenced by the genetic variation that naturally exists within the ribosomal RNA.

Science , this issue p. [495][1]

[1]: /lookup/doi/10.1126/science.aaf7040
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Lipid metabolism is associated with developmental epigenetic programming

Maternal diet and metabolism impact fetal development. Epigenetic reprogramming facilitates fetal adaptation to these in utero cues.
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The plant engineer

The plant engineer | Research Biotechnologies | Scoop.it
As a child, Dan Voytas developed a green thumb and business savvy running his own seedling business. Now, marrying his academic research with a company, he's poised to reshape 21st century agriculture. Over the past 20 years, he has pioneered new ways of precisely editing a crop's DNA to give it new traits or delete undesirable ones. It's an approach that is potentially more powerful than the traditional way of making genetically modified (GM) crops, and because it leaves no foreign DNA behind, it could free these products from the stigma and regulatory burden of being labeled as GM organisms. But to get to this point, he has had to overcome recalcitrant technologies, navigate intellectual property fights, and endure commercial failures.

Via Christophe Jacquet, Jean-Pierre Zryd
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Modulation of Behavioral Deficits and Neurodegeneration by Tannic Acid in Experimental Stroke Challenged Wistar Rats. - PubMed - NCBI

Mol Neurobiol. 2016 Sep 27. [Epub ahead of print]
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Monsanto Buys Rights to CRISPR | The Scientist Magazine®

The US agribusiness secures a global, nonexclusive licensing agreement from the Broad Institute to use the gene-editing technology for agricultural applications.
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New Trends in Aryl Hydrocarbon Receptor Biology. - PubMed - NCBI

Front Cell Dev Biol. 2016 May 11;4:45. doi: 10.3389/fcell.2016.00045. eCollection 2016. Review
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Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells. - PubMed - NCBI

PLoS One. 2016 Dec 1;11(12):e0167361. doi: 10.1371/journal.pone.0167361. eCollection 2016.
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Role of gut microbiota in atherosclerosis : Nature Reviews Cardiology : Nature Research

Role of gut microbiota in atherosclerosis : Nature Reviews Cardiology : Nature Research | Research Biotechnologies | Scoop.it
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Adipose tissue browning and metabolic health : Nature Reviews Endocrinology : Nature Research

Adipose tissue browning and metabolic health : Nature Reviews Endocrinology : Nature Research | Research Biotechnologies | Scoop.it
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Combination of the anthocyanidins malvidin and peonidin attenuates lipopolysaccharide-mediated inflammatory gene expression in primary human adipoc... - PubMed - NCBI

Nutr Res. 2016 Nov 10. pii: S0271-5317(16)30352-9. doi: 10.1016/j.nutres.2016.11.003. [Epub ahead of print]
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Gut microbial metabolism defines host metabolism: an emerging perspective in obesity and allergic inflammation. - PubMed - NCBI

Obes Rev. 2016 Nov 11. doi: 10.1111/obr.12484. [Epub ahead of print] Review
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Anti-inflammatory protection afforded by cyanidin-3-glucoside and resveratrol in human intestinal cells via Nrf2 and PPAR-γ: Comparison with 5-amin... - PubMed - NCBI

Chem Biol Interact. 2016 Nov 3. pii: S0009-2797(16)30525-7. doi: 10.1016/j.cbi.2016.11.003. [Epub ahead of print]
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Water-saving farming tech says 'sayonara' to soil- Nikkei Asian Review

Water-saving farming tech says 'sayonara' to soil- Nikkei Asian Review | Research Biotechnologies | Scoop.it
TOKYO -- Working with a startup, Japanese chemical company Denka has commercialized a new cultivation system that eliminates the need for soil.The met
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Topical treatment of green tea polyphenols emulsified in carboxymethyl cellulose protects against acute ultraviolet light B-induced photodamage in ... - PubMed - NCBI

Photochem Photobiol Sci. 2016 Oct 5;15(10):1264-1271.
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Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27 - Food & Function (RSC Publishing)

Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27 - Food & Function (RSC Publishing) | Research Biotechnologies | Scoop.it
Indigestible resistant starches (RS) are substrates for gut-microbial metabolism and have been shown to attenuate intestinal inflammation but the supporting evidence is inconsistent and lacks mechanistic explanation. We have recently reported dietary RS type 4 (RS4) induced improvements in immunometabolic fu
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Pistacia lentiscus fruit oil reduces oxidative stress in human skin explants caused by hydrogen peroxide. - PubMed - NCBI

Biotech Histochem. 2016 Sep 27:1-12. [Epub ahead of print]
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Japanese wins Nobel Prize for autophagy discovery- Nikkei Asian Review

Japanese wins Nobel Prize for autophagy discovery- Nikkei Asian Review | Research Biotechnologies | Scoop.it

TOKYO -- This year's Nobel Prize in physiology or medicine has been awarded to Yoshinori Osumi of Japan, for his discoveries of mechanisms for autopha

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