Because all cancers occur due to abnormalities in DNA, scientists are able to use DNA sequencing to analyze the mutations in each patient's DNA.
Brian Shields's insight:
This is great news regarding the adcancement in personalized medicine. The ability to review a patient's DNA without an invasive biopsy may signficantly help clinicians target the right medicines for the right people, and also allow for a non-invasive manner of tracking acquired mutations during treatment.
Important quote below:
"This ground-breaking study uses brand new technology--the multiregional sequencing research tool will lead to routine practice leading to lower cost," said Eleftherios P. Diamandis, MD, PhD, FRCP(C), FRSC, Head of Clinical Biochemistry at Mount Sinai Hospital and Editor of this special issue of Clinical Chemistry. "This is the first time analysis has been done non-invasively instead of performing a biopsy on human tissue. The proof of principle is demonstrated and will be more readily available and cost effective in the future."
Next Generation Gene Sequencing Brings Personal Genomics Closer (RT @PedCancerCare: Lot of talk, but next generation gene sequencing research at @ChildrensPhila brings reality of personal genomics closer http://t.co/HscZDuK...)...
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