Wonder if VEGF and PL4 would predict #cardiotoxicity? RT @harvardmed: Biomarkers signal early #heart txp rejection: http://t.co/kfABICSH
Brian Shields's insight:
Important quote from the article:
"The discovery, if validated in a larger population of patients, could be a boon for transplant recipients by allowing their care team to address rejection-related problems before the risk of graft loss becomes too high. "There are a number of medications available and in the pipeline to treat CAV and other forms of chronic rejection," said Briscoe. "The problem has been detecting disease early, when these drugs would be most effective." "
Study Challenges FDA on PlavixWall Street Journal"I tend to agree that it may be a little premature in genotyping everyone before giving them the drug," said Gordon Tomaselli, president of the American Heart Association and chief of cardiology at...
A combination of three blood-borne proteins may bolster efforts to prevent graft loss years after transplantBOSTON, Dec.
Brian Shields's insight:
"Researchers at Boston Children's Hospitalhave found a combination of biomarkers related to blood vessel and tissue injury that, when measured together, could signal when a transplanted heart is becoming damaged to the point of failure, a process that is often undetected. The markers would give doctors an opportunity to intervene and save a recipient's heart, and also provide a starting point for identifying long-term rejection biomarkers for several kinds of organ transplants.
The research team—led by Kevin P. Daly, MD, and David M. Briscoe, MD, of the Transplant Research Program (TRP) at Boston Children's Hospital, and S. Ananth Karumanchi, MD, of Beth Israel Deaconess Medical Center—published their findings online Dec. 26 in the Journal of Heart and Lung Transplantation."
Biomarker Tests Could Significantly Speed Up Heart Attack DiagnosisMedical News TodayAccording to a study in the December issue of JAMA, using a contemporary or highly sensitive test for levels of the biomarker troponin I, a protein in the muscle...
Nissen and Topol Clash Over Genetics and Personalized MedicineForbesTopol has been a leading advocate for genomics and personalized medicine, while Nissen has now publicly questioned whether the enthusiasm for these technologies has outpaced their...
One of the most common reasons people go to the emergency room is for serious chest pains. Time is crucial when someone is having a heart attack. If doctors don't make a diagnosis quickly, it can mean the difference between life and death.
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