Biomarker
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“Over the past two decades, the promise of accelerated drug development and personalized medicine have brought heighten attention to the field of biomarker. But do you really know what biomarker are, how they are developed, and how they are used?”
Curated by Thierry Sornasse
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Created Aug 12, 2011
Created by Thierry S...
Updated Oct 30, 2011
Posts 211
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tsornasse.blogspot.com (via @tsornasse) - October 30, 2011 8:59 PM

Integrated Biomarker Strategy: The Common Rule: Human Samples, Ethics, and the Future of Biomarker Research

The Common Rule: Human Samples, Ethics, and the Future of Biomarker Research: TheCommon Rule is the regulation g...
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news.feedzilla.com (via @FZpsychiatry) - October 29, 2011 2:33 PM

New Study Method Reveals Possible Biomarker for Depression

New Study Method Reveals Possible Biomarker for Depression (Psychcentral) http://t.co/XswGAbuC...
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arthritis-research.com (via @RA_Wisdom) - October 29, 2011 11:06 AM

Arthritis Research & Therapy | Abstract | The soluble biomarker calprotectin (a S100 protein) is associated to ultrasonographic synovitis scores and is sensitive to change in patients with rheumato...

Calprotectin (MRP8/MRP14, S100A8/A9) is associated with disease activity in patients with rheumatoid arthritis (RA). Ultrasonography (US) is a reliable method for evaluation of synovitis (B-mode (BM) and power Doppler (PD)).
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www.ncbi.nlm.nih.gov (via @DetailJunkie) - October 24, 2011 10:00 PM

Elevated production of galectin-3 is correla... [Int J Rheum Dis. 2011] - PubMed - NCBI

PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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www.genomeweb.com (via @valuecreatibee) - October 22, 2011 10:18 PM

Oligo-Based Protein Capture Tools Allow Simultaneous Reporting of Genetic, Proteomic Biomarker Data | ProteoMonitor | Proteomics | GenomeWeb

http://t.co/3XLVNdkj Oligo-Based Protein Capture Tools Allow Simultaneous Reporting of Genetic, Proteomic Biomarker Data...
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www.genengnews.com (via @Meng_GenScript) - October 21, 2011 1:26 PM

GEN | Analysis & Insight: FDA Details Requirements for Regulatory Submissions of Genomic Biomarkers

Agency hopes efforts to streamline biomarker development will advance more into the clinic.
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www.newswise.com (via @rioconsulado) - October 21, 2011 1:25 PM

Biomarker Detects Graft-Versus-Host-Disease in Cancer Patients After Bone Marrow Transplant

A University of Michigan Health System-led team of researchers has found a biomarker they believe can help rapidly identify one of the most serious complications in cancer patients after a bone marrow transplant.
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www.sciencedaily.com (via @RoxanneChristie) - October 20, 2011 11:27 AM

Biomarker for autism discovered

Siblings of people with autism show a similar pattern of brain activity to that seen in people with autism when looking at emotional facial expressions.
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www.medcitynews.com - October 19, 2011 10:42 PM

PSA test recommendation needed a little healthcare PR help

Last Friday at 3 p.m., the Agency for Healthcare Research and Quality held a telephone briefing to inform the press and public about the U.S.
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www.medicalnewstoday.com (via @mnt_cardiovasc) - October 19, 2011 11:21 AM

Biomarker-Guided Heart Failure Treatment Significantly Reduces Complications

Adding regular testing for blood levels of a biomarker of cardiac distress to standard care for the most common form of heart failure may significantly reduce the incidence of cardiovascular comp (Biomarker-Guided Heart Failure Treatment Significantly...
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www.plosone.org - October 18, 2011 12:31 PM

PLoS ONE: Neuropathologic Correlates of Hippocampal Atrophy in the Elderly: A Clinical, Pathologic, Postmortem MRI Study

PLoS ONE: Neuropathologic Correlates of Hippocampal Atrophy in the Elderly: A Clinical, Pathologic, Postmortem MRI Study

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medicalxpress.com - October 17, 2011 1:13 PM

First genome-wide association study for dengue identifies candidate susceptibility genes

Researchers in South East Asia have identified two genetic variants associated with increased susceptibility to severe dengue.
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newsroom.lilly.com (via @pharmamagic) - October 17, 2011 1:10 PM

Eli Lilly and Company - GE and Lilly Achieve Significant Advancement in Cancer Research

Lilly and GE collabo creates biomarker mapping for cancer - compressing R&D timelines and increase therapy targets http://t.co/eo5QfLVt...
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biomarkercommons.org - October 29, 2011 2:35 PM

Neuronetrix Helps Put ERP Biomarkers in the Spotlight at Alzheimer's Clinical Trial Conference

Neuronetrix today announced their sponsorship of CTAD 2011 (Clinical Trials on Alzheimer's Disease) to be held November 3-5 in San Diego, CA.
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www.news-medical.net - October 29, 2011 11:08 AM

Blood biomarker panel can predict survival in IPF patients - News-Medical.net

Blood biomarker panel can predict survival in IPF patientsNews-Medical.net"This biomarker panel has predictive power that can guide our treatment plan.
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tsornasse.blogspot.com - October 24, 2011 10:01 PM

Overhaul of the FDA Medical Device Pre-Market Approval Program: What Does It Means for Diagnostics

OnOctober 19th, the FDA Center for Devices and Radiation Health (CDRH)released its Medical Device Pre-Market Programs: An Overview of FDA Actions (link).  This document presents the center’s review ofthe processes of pre-market approval of all...
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tsornasse.blogspot.com (via @tsornasse) - October 24, 2011 9:59 PM

Integrated Biomarker Strategy: Enabling Retrospective Biomarker Studies: Resolving the Conflict between Short and Long Term Goals

Enabling Retrospective Biomarker Studies: Resolving the Conflict between Short and Long Term Goals: In thefield ...
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biomarkercommons.org - October 22, 2011 11:43 AM

Metabolomics Insight Into Periodontal Disease Published in the Journal of Dental Research

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announced today the publication of "Metabolomics Revealed Elevated Macromolecular Degradation in Periodontal Disease," in the Journal of Dental Research.
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medicalxpress.com - October 21, 2011 1:25 PM

New instrument helps researchers see how diseases start and develop in minute detail

Magnetic resonance imaging (MRI) is an established technique which over the years has made it possible for researchers and healthcare professionals to study biological phenomena in the body without using ionising radiation, for example X-rays.
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www.la-press.com - October 20, 2011 11:30 AM

News: Press Release: U Of M Researchers Find Gene Biomarkers Can Predict A Patient’s Ovarian Cancer Therapy Response & Survival

MINNEAPOLIS/ST. PAUL (October 12, 2011) — University of Minnesota Medical School researchers have identified gene biomarkers that can predict which patients with advanced stages of ovarian cancer (stages III-IV) will respond to standard chem...
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www.scoop.it (via @HDCircle) - October 20, 2011 11:27 AM

A potential biomarker for SOD1 ALS | MDA/ALS Newsmagazine | Amyotrophic Lateral Sclerosis (ALS) | Scoop.it

An MDA-supported team of scientists has identified specific changes that occur in the spinal cord prior to disease onset in people with familial (inherited) ALS related to mutations in the SOD1 gene.
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www.marketwatch.com (via @pndblog) - October 19, 2011 10:40 PM

The Michael J. Fox Foundation and The Kinetics Foundation Collaborate on Search for Parkinson's Biomarker

Michael J.Fox Foundation, Kinetics Foundation Collaborate on Search for #Parkinson's Biomarker http://t.co/QXZrrwyS #health...
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tsornasse.blogspot.com - October 19, 2011 12:21 AM

Volumetric MRI and Neuropathology in the Elderly: a Key Bridging Study

In theOctober 17th issue of PLoS One, Robert Dawe and colleagues, from theIllinois Institute of Technology and the Rush Alzheimer’s Disease Center, presentthe results of a key bridging study of volumetric MRI correlation with normalaging,...
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www.pcrf.org.uk (via @PanCanResearch) - October 17, 2011 1:17 PM

Changes in saliva bacteria may offer biomarker for pancreatic cancer · News · Pancreatic Cancer Research Fund

Pancreatic Cancer Research Fund (Small-scale study, but could be interesting: biomarkers for diagnosis are much needed http://t.co/i73ZMuka...)...
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medicalxpress.com - October 17, 2011 1:12 PM

Largest ever genetic study of liver function could point the way to new treatments

Researchers have identified a large number of areas in the human genetic code that are involved in regulating the way in which the liver functions, in a new study of over 61,000 people, published today in the journal Nature Genetics.
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