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Rescooped by Mel Melendrez-Vallard from Bioinformatics, Comparative Genomics and Molecular Evolution
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How Computers Are Changing Biology

How Computers Are Changing Biology | Tools and tips for scientific tinkers and tailors | Scoop.it
Sophisticated computer models and simulations are replacing test tubes and beakers. This revolution in biology research is redefining medicine, agriculture, and more.

Via Arjen ten Have
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Arjen ten Have's curator insight, May 12, 4:08 PM

A rather positive view: as an independent source of evidence. I dig it but people that do not work on biocomputation just do not.

Tools and tips for scientific tinkers and tailors
Next gen sequencing, bioinformatics, virology, microbiology, genomes, zoonoses, workshops, conferences, all-around science geekery
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Reagent contamination can critically impact sequence-based microbiome analyses

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Interesting discussion in comment section Reagent contamination can impacts microbiome analyses

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Comparison of Contact Patterns Relevant for Transmission of Respiratory Pathogens in Thailand and the Netherlands Using Respondent-Driven Sampling

Comparison of Contact Patterns Relevant for Transmission of Respiratory Pathogens in Thailand and the Netherlands Using Respondent-Driven Sampling | Tools and tips for scientific tinkers and tailors | Scoop.it
by Mart L. Stein, Jim E. van Steenbergen, Vincent Buskens, Peter G. M. van der Heijden, Charnchudhi Chanyasanha, Mathuros Tipayamongkholgul, Anna E. Thorson, Linus Bengtsson, Xin Lu, Mirjam E. E.
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Controlling Cyanobacterial Blooms in Hypertrophic Lake Taihu, China: Will Nitrogen Reductions Cause Replacement of Non-N2 Fixing by N2 Fixing Taxa?

by Hans W. Paerl, Hai Xu, Nathan S. Hall, Guangwei Zhu, Boqiang Qin, Yali Wu, Karen L. Rossignol, Linghan Dong, Mark J. McCarthy, Alan R.
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NIH scientists determine how environment contributes to several human diseases

NIH scientists determine how environment contributes to several human diseases | Tools and tips for scientific tinkers and tailors | Scoop.it

Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. These damaged molecules trigger cell death that produces some human diseases, according to the researchers. The work, appearing online Nov. 17 in the journal Nature, provides a possible explanation for how one type of DNA damage may lead to cancer, diabetes, hypertension, cardiovascular and lung disease, and Alzheimer’s disease.


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Researchers move ultrafast, low-cost DNA sequencing technology a step closer to reality

A team of scientists from Arizona State University's Biodesign Institute and IBM's T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.
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Genome Biology | Full text | Next-generation pathogen genomics

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Mixture models reveal multiple positional bias types in RNA-Seq data and lead to accurate transcript concentration estimates

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Human infectious diseases in the genomics era: where do we go from here?

Ripudaman K Bains is the editor of the Genome Biology special issue content on the ‘genomics of infectious diseases’, and introduces the collection in this editorial.
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Single cell genomics of bacterial pathogens: outlook for infectious disease research

Editorial summaryGenomic sequencing from single cells is a powerful tool in microbiology and holds great promise for infectious disease research.
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Techniques for positional information integration on the transcriptome

The recent explosion of high-throughput sequencing methods applied to RNA molecules is allowing us to go beyond the description of sequence variants and their relative abundances, as measured by RNA-seq.
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A robust statistical framework for reconstructing genomes from metagenomic data

A robust statistical framework for reconstructing genomes from metagenomic data Dongwan Don Kang, Jeff Froula, Rob Egan, Zhong Wang doi: We present software that reconstructs genomes from shotgun m...
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Current data show no signal of Ebola virus adapting to humans

Current data show no signal of Ebola virus adapting to humans Stephanie J. Spielman, Austin G. Meyer, Claus O. Wilke doi: Gire et al. (Science 345:1369--1372, 2014) analyzed 81 complete genomes sam...
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CoreGenomics: Ion Proton amplicons for clinical molecular diagnostics

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A case of brucellosis mimicking Crimean-Congo hemorrhagic fever

Brucellosis is a zoonotic disease caused by Brucella spp. that is transmitted to humans by the ingestion of unpasteurized milk and other dairy products from infected animals or through close contact with secretions.
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Long-read, whole-genome shotgun sequence data for five model organisms

Long-read, whole-genome shotgun sequence data for five model organisms | Tools and tips for scientific tinkers and tailors | Scoop.it
Scientific Data, Published online: 25 November 2014; | doi:10.1038/sdata.2014.45
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Researchers move ultrafast, low-cost DNA sequencing technology a step closer to reality

A team of scientists from Arizona State University's Biodesign Institute and IBM's T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.
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Epidemiologic data and pathogen genome sequences: a powerful synergy for public health

Epidemiologists aim to inform the design of public health interventions with evidence on the evolution, emergence and spread of infectious diseases.
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Splash of Cold Water for Clinical Genomics at Cold Spring Harbor Personal ... - Bio-IT World

Splash of Cold Water for Clinical Genomics at Cold Spring Harbor Personal ...
Bio-IT World
“I think the analytical validity is not equivalent to other medical tests.
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Genomic analysis of emerging pathogens: methods, application and future trends

The number of emerging infectious diseases is increasing. Characterizing novel or re-emerging infections is aided by the availability of pathogen genomes.
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Rescooped by Mel Melendrez-Vallard from Virology and Bioinformatics from Virology.ca
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Five ingredients to become a bioinformatician. - atcgeek

How to become a bioinformatician? Many people, at different career stages, are trying to answer this question, looking for the best path to achieve the required knowledge to become a bioinformatician.

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Serological Evidence of Henipavirus Exposure in Cattle, Goats and Pigs in Bangladesh

by Sukanta Chowdhury, Salah Uddin Khan, Gary Crameri, Jonathan H. Epstein, Christopher C. Broder, Ausraful Islam, Alison J. Peel, Jennifer Barr, Peter Daszak, Lin-Fa Wang, Stephen P.
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Avian Flu Diary: CIDRAP: Migrations in West Africa seen as challenge to stopping Ebola

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How Well Can We Detect Shifts in Rates of Lineage Diversification? A Simulation Study of Sequential AIC Methods

How Well Can We Detect Shifts in Rates of Lineage Diversification? A Simulation Study of Sequential AIC Methods Michael R May, Brian R Moore doi: Evolutionary biologists have long been fascinated b...
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The threat of zoonotic diseases

The threat of zoonotic diseases | Tools and tips for scientific tinkers and tailors | Scoop.it
While zoonotic EIDs are a major concern globally, their impact in less developed countries is disproportionately high.
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A virus that melts sea stars

Sea star associated densovirus might be the cause of a lethal disease that melts these marine invertebrates into piles of slime and ossicles.
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