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Pico-World of Molecular Bioscavengers, Mops and Sponges Being Designed - Science Daily (press release)

Pico-World of Molecular Bioscavengers, Mops and Sponges Being Designed - Science Daily (press release) | Bioinformatics | Scoop.it
“Pico-World of Molecular Bioscavengers, Mops and Sponges Being Designed Science Daily (press release) Khare is currently an assistant professor at Rutgers University.”
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BMC Genetics | Abstract | Nitrogen-metabolism related genes in barley - haplotype diversity, linkage mapping and associations with malting and kernel quality parameters

Background: Several studies report about intra-specific trait variation of nitrogen-metabolism related traits, such as N(itrogen)-use efficiency, protein content, N-storage and remobilization in barley and related grass species. The goal of this study was to assess the intra-specific genetic diversity present in primary N-metabolism genes of barley and to investigate the associations of the detected haplotype diversity with malting and kernel quality related traits. Results: Partial sequences of five genes related to N-metabolism in barley (Hordeum vulgare L.) were obtained, i.e. nitrate reductase 1, glutamine synthetase 2, ferredoxin-dependent glutamate synthase, aspartate aminotransferase and asparaginase. Two to five haplotypes in each gene were discovered in a set of 190 various varieties. The development of 33 SNP markers allowed the genotyping of all these barley varieties consisting of spring and winter types. Furthermore, these markers could be mapped in several doubled haploid populations. Cluster analysis based on haplotypes revealed a more uniform pattern of the spring barleys as compared to the winter barleys. Based on linear model approaches associations to several malting and kernel quality traits including soluble N and protein were identified. Conclusions: A study was conducted to investigate the presence of sequence variation of several genes related to the primary N-metabolism in barley. The detected diversity could be related to particular phenotypic traits. Specific differences between spring and winter barleys most likely reflect different breeding aims. The developed markers can be used as tool for further genetic studies and marker-assisted selection during breeding of barley.
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HIV vaccine produces no adverse effects in trials

HIV vaccine produces no adverse effects in trials | Bioinformatics | Scoop.it
"Phase I Clinical Trial (SAV CT 01) of the first and only preventative HIV vaccine based on a genetically modified killed whole virus (SAV001-H) has been successfully completed with no adverse effects in all patients, Western and Sumagen Canada Inc. announced today."
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Fernando Martin-Sanchez - The Conversation

Fernando Martin-Sanchez - The Conversation | Bioinformatics | Scoop.it
“ Fernando Martin-Sanchez The Conversation He then received his M.Sc. degree in Knowledge Engineering and a PhD in Informatics from the Technical University (UPM), also in Madrid.”
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Government Support Amplifying Bioinformatics Research

Government Support Amplifying Bioinformatics Research | Bioinformatics | Scoop.it
“ Press Release issued Sep 3, 2013: Bioinformatics market is growing enormously across the globe on back of rising government support for research and development in the sector.”
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CDC - Public Health Informatics Fellowship Program

CDC - Public Health Informatics Fellowship Program | Bioinformatics | Scoop.it
“ The Public Health Informatics Fellowship Program (PHIFP) is a 2-year paid fellowship to apply information science and technology to the practice of public health.”
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BMC Bioinformatics | Full text | 4273¿: Bioinformatics education on low cost ARM hardware

“Teaching bioinformatics at universities is complicated by typical computer classroom settings. As well as running software locally and online, students should gain experience of systems administration.”
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Computational biology: A recipe for ligand-binding proteins - Nature.com

“Computational biology: A recipe for ligand-binding proteins Nature.com Broadening this set of protein–ligand pairs with synthetic proteins that are specific for ligands of choice could transform the development of biosensors, protein-based drugs,...”
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Emerging Microbes & Infections - Zoonotic simian foamy virus in Bangladesh reflects diverse patterns of transmission and co-infection

Emerging Microbes & Infections - Zoonotic simian foamy virus in Bangladesh reflects diverse patterns of transmission and co-infection | Bioinformatics | Scoop.it
Simian foamy viruses (SFVs) are ubiquitous in non-human primates (NHPs). As in all retroviruses, reverse transcription of SFV leads to recombination and mutation. Because more humans have been shown to be infected with SFV than with any other simian borne virus, SFV is a potentially powerful model for studying the virology and epidemiology of viruses at the human/NHP interface. In Asia, SFV is likely transmitted to humans through macaque bites and scratches that occur in the context of everyday life. We analyzed multiple proviral sequences from the SFV gag gene from both humans and macaques in order to characterize retroviral transmission at the human/NHP interface in Bangladesh. Here we report evidence that humans can be concurrently infected with multiple SFV strains, with some individuals infected by both an autochthonous SFV strain as well as a strain similar to SFV found in macaques from another geographic area. These data, combined with previous results, suggest that both human-facilitated movement of macaques leading to the introduction of non-resident strains of SFV and retroviral recombination in macaques contribute to SFV diversity among humans in Bangladesh.
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TeselaGen, Redbiotech to Co-create Herpesvirus Vaccine Library - GenomeWeb

TeselaGen, Redbiotech to Co-create Herpesvirus Vaccine Library - GenomeWeb | Bioinformatics | Scoop.it
“TeselaGen, Redbiotech to Co-create Herpesvirus Vaccine Library GenomeWeb This week, TeselaGen Biotechnology and Redbiotec announced their plans to build a library that will be used to develop vaccines for the Herpesvirus.”
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Health News - Common virus is a new target for cancer treatment

Health News - Common virus is a new target for cancer treatment | Bioinformatics | Scoop.it
"Treatment for the common cytomegalovirus (CMV) has been shown to give seriously ill cancer patients a much improved prognosis."
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PLOS Computational Biology: The Next Generation of Transcription Factor Binding Site Prediction

PLOS Computational Biology: The Next Generation of Transcription Factor Binding Site Prediction | Bioinformatics | Scoop.it
“ PLOS Computational Biology is an open-access”
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