Biochemistry and Microbiology at UVic
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Biochemistry and Microbiology at UVic
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Biochemistry and Microbiology - University of Victoria

 

This topic will highlight some of the research and events going on in our Department.

 

You can find our web page at: 

www.uvic.ca/science/biochem

 

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Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide

Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide | Biochemistry and Microbiology at UVic | Scoop.it

Science 22 July 2011:
Vol. 333 no. 6041 pp. 463-467
Michelle L. Tonkin1,*, Magali Roques2,*, Mauld H. Lamarque2, Martine Pugnière3, Dominique Douguet4, Joanna Crawford1, Maryse Lebrun2,*†, Martin J. Boulanger1,*†

 

Apicomplexan parasites such as Toxoplasma gondii and Plasmodium species actively invade host cells through a moving junction (MJ) complex assembled at the parasite–host cell interface. We have determined the structure of TgAMA1 complexed with a RON2 peptide at 1.95 angstrom resolution. Besides providing insights into host cell invasion by apicomplexan parasites, the structure offers a basis for designing therapeutics targeting these global pathogens.

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PLOS Computational Biology: Viral Phylodynamics

PLOS Computational Biology: Viral Phylodynamics | Biochemistry and Microbiology at UVic | Scoop.it
PLOS Computational Biology is an open-access
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NSERC - E.W.R. Steacie Memorial Fellowships

NSERC - E.W.R. Steacie Memorial Fellowships | Biochemistry and Microbiology at UVic | Scoop.it
NSERC - E.W.R.Steacie Memorial Fellowships...

 

Winner 2012

Alisdair Boraston
Biochemistry and Microbiology
University of Victoria

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