As I have mentioned elsewhere I really like many of the ideas embedded in TinkerCell - Deepak Chandran did a great job in its design and implementation. If you want to experiment with synthetic biology this is a great example for simulating a baterial photography system. Click on the image or title to learn more.
Biologists have of late been spared these dilemmas, as President Nixon officially dismantled the nation’s biological weapons program in 1969. But synthetic biology is about transforming biology into an engineering discipline, so perhaps it’s no surprise that the field is confronting the same sorts of questions that may be familiar to physical scientists and engineers.
Triton says it has developed a synthetic biology platform that also uses algae to produce “high value” proteins. The company says it already is producing complex proteins, enzymes, and other biologics that are cost-effective and can be immediately used in agricultural, pharmaceutical, and other retail markets.
Currently, for genomic editing in cultured cells, two plasmids encoding a pair of TALENs are co-transfected, followed by limited dilution to isolate cell colonies with the intended genomic manipulation. However, uncertain transfection efficiency becomes a bottleneck, especially in hard-to-transfect cells, reducing the overall efficiency of genome editing. We have developed a robust TALENs system in which each TALEN plasmid also encodes a fluorescence protein. Thus, cells transfected with both TALEN plasmids, a prerequisite for genomic editing, can be isolated by fluorescence-activated cell sorting. Our improved TALENs system can be applied to all cultured cells to achieve highly efficient genomic editing. Furthermore, an optimized procedure for genomic editing using TALENs is also presented. We expect our system to be widely adopted by the scientific community.
The EPSRC Centre for Doctoral Training in Synthetic Biology will combine world-leading expertise in engineering and the physical and life sciences at the Universities of Oxford, Bristol and Warwick to create the next generation of industrial and academic leaders in the important new field of synthetic biology.
When researchers synthesized the poliovirus from scratch 10 years ago, it was a major feat in the rapidly growing field of synthetic biology. For the first time, scientists had chemically stitched together bits of DNA to create a functional virus without the guidance of a biological template.
Now the virologist who led that team, Eckard Wimmer of Stony Brook University, continues to push the field by constructing designer viruses and, potentially, designer vaccines. New York Genome Center spoke with Wimmer recently about the future of synthetic biology.
Synthetic biology is a field of science that has been emerging in the last few years and could have a significant future impact with the potential to pro-actively manage biology and reshape many industrial sectors.
Investments in SB companies could be profitable. Intrexon is in the realm of “synthetic biology,” a more radical version of existing biotech genetic tweaking that includes reengineering living cells from the ground up. In one day only shares went up 1.5 B USD!
The emergence of synthetic biology and DIYbio has increased the likelihood that Al Qaeda will succeed in developing biological WMDs. The low cost and significantly reduced level of necessary expertise may change how many non-state actors view biological weapons as a worthwhile investment. This is not to say that suddenly anyone can make a weapon or that it is easy. To the contrary making an effective biological weapon will still be difficult, only much easier and cheaper than it has been in the past.
A nasal vaccine developed by researchers at Duke University provided protective immunity against West Nile virus in mice after two doses, according to new research presented recently at the American Society for ...