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Type 1 diabetes—progress and prospects : The Lancet

Type 1 diabetes—progress and prospects. By - The Lancet

Via Ellen H Ullman, MSW
Gilbert Faure au nom de l'ASSIM's insight:

link with a report on paediatric diabetes in UK

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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert Faure au nom de l'ASSIM
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Autoimmunity

Pathology, Diagnosis and Therapy

Gilbert Faure au nom de l'ASSIM's insight:

Autoimmunity is indeed one of the biggest challenge of Immunology!

Understanding the mechanisms of this physiological immune phenomenon inducing such a diverse array of diseases, joint and muscular, digestive, endocrinological, neurological, cutaneous..

 

Improving the molecular and cellular tools in use for a few decades for diagnosis and follow-up of patients, perhaps screening in the future

Mastering the molecular and cellular therapies to treat patients.

 

You can also find relevant informations on some other topics curated  here such as

Rheumatology http://www.scoop.it/t/rheumatology-rhumatologie

Immunology and biotherapies http://www.scoop.it/t/immunology-and-biotherapies

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Altered CD161bright CD8+ Mucosal Associated Invariant T (MAIT)-Like Cell Dynamics and Increased Differentiation States among Juvenile Type 1 Diabetics

Altered CD161bright CD8+ Mucosal Associated Invariant T (MAIT)-Like Cell Dynamics and Increased Differentiation States among Juvenile Type 1 Diabetics | AUTOIMMUNITY | Scoop.it
by Robert Z. Harms, Kristina M. Lorenzo, Kevin P. Corley, Monina S. Cabrera, Nora E. Sarvetnick
Type 1A diabetes (T1D) is believed to be caused by immune-mediated destruction of β-cells, but the immunological basis for T1D remains controversial.
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Frontiers | Environment, autoantibodies and autoimmunity | B Cell Biology

Environment, autoantibodies and autoimmunity.

Kenneth Michael Pollard, PhD
Department of Molecular and Experimental Medicine,
The Scripps Research Institute,
La Jolla, CA, US...
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IL-35 and Autoimmunity: a Comprehensive Perspective. - PubMed - NCBI

Clin Rev Allergy Immunol. 2015 Jan 27. [Epub ahead of print]
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Graphene Oxide Interfaces in Serum Based Autoantibody Quantification - Analytical Chemistry (ACS Publications)

Graphene Oxide Interfaces in Serum Based Autoantibody Quantification - Analytical Chemistry (ACS Publications) | AUTOIMMUNITY | Scoop.it
Graphene oxide interfaces in serum based autoantibody quantification http://t.co/r2oiKNGBIN
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Unconventional apoptosis of polymorphonuclear neutrophils (PMN): st... - PubMed - NCBI

Clin Exp Immunol. 2015 Jan;179(1):75-84. doi: 10.1111/cei.12412. Research Support, Non-U.S. Gov't
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The association of cytotoxic T-lymphocyte antigen-4 + 49A/G and CT60 polymorphisms with type 1 diabetes and latent autoimmune diabetes in Chinese adults - Springer

The association of cytotoxic T-lymphocyte antigen-4 + 49A/G and CT60 polymorphisms with type 1 diabetes and latent autoimmune diabetes in Chinese adults - Springer | AUTOIMMUNITY | Scoop.it
The association of cytotoxic T-lymphocyte antigen-4 + 49A/G and CT60 polymorphisms with type 1 diabetes and la... http://t.co/uQ6YL50x0G
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Self-Organized Criticality Theory of Autoimmunity

Self-Organized Criticality Theory of Autoimmunity | AUTOIMMUNITY | Scoop.it
Background
The cause of autoimmunity, which is unknown, is investigated from a different angle, i.e., the defect in immune ‘system’, to explain the cause of autoimmunity.
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Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts

Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts | AUTOIMMUNITY | Scoop.it
by Michael E. Johnson, J. Matthew Mahoney, Jaclyn Taroni, Jennifer L. Sargent, Eleni Marmarelis, Ming-Ru Wu, John Varga, Monique E. Hinchcliff, Michael L.
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King's College London signs licence agreement with UCB in immunology and ... - Science Business

King's College London signs licence agreement with UCB in immunology and ... - Science Business | AUTOIMMUNITY | Scoop.it
King’s College London announced that it has entered an exclusive licence agreement with UCB that grants the company the rights to develop a peptide-based immunotherapy programme for type 1 diabetes.
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SLU Researcher Prevents Type I Diabetes in Lab - Saint Louis University

SLU Researcher Prevents Type I Diabetes in Lab - Saint Louis University | AUTOIMMUNITY | Scoop.it
A new approach developed by researcher Thomas Burris, Ph.D., stops the destruction of beta cells and preserves insulin production.
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A Comparison of Assays for Accurate Copy Number Measurement of the Low-Affinity Fc Gamma Receptor Genes FCGR3A and FCGR3B

A Comparison of Assays for Accurate Copy Number Measurement of the Low-Affinity Fc Gamma Receptor Genes FCGR3A and FCGR3B | AUTOIMMUNITY | Scoop.it
by Umi Shakina Haridan, Umairah Mokhtar, Lee R. Machado, Abu Thalhah Abdul Aziz, Rafidah Hanim Shueb, Masliza Zaid, Benedict Sim, Mahiran Mustafa, Nik Khairudin Nik Yusof, Christopher K. C. Lee, Suhaili Abu Bakar, Sazaly AbuBakar, Edward J.
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Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

RT @toates_19: Great stuff as usual in @ASH_hematology #BloodJournal
Interest: http://t.co/V8PPXUHkwp #STAT3
Practice: http://t.co/sdDIYvdE…
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Using Parasites to Fight Autoimmune Diseases - IsraCast

Using Parasites to Fight Autoimmune Diseases - IsraCast | AUTOIMMUNITY | Scoop.it
Using Parasites to Fight Autoimmune Diseases IsraCast Indeed, says the world-renowned Israeli autoimmunologist, prolific author and founder and editor of the Israel Medical Association Journal, Autoimmunity Reviews and J Autoimmunity: “Women are...
Gilbert Faure au nom de l'ASSIM's insight:

Y Shoenfeld

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Molecular mimicry as a mechanism for food immune reactivities and a... - PubMed - NCBI

Altern Ther Health Med. 2015;21(1 Suppl 1):34-45.
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16th International Coeliac Disease Symposium, 21–24 June 2015, Prague, Czech Republic

16th International Coeliac Disease Symposium, 21–24 June 2015, Prague, Czech Republic | AUTOIMMUNITY | Scoop.it
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IL-17A-producing CD8+T cells as therapeutic targets in autoimmunity, Expert Opinion on Therapeutic Targets, Informa Healthcare

IL-17A-producing CD8+T cells as therapeutic targets in autoimmunity, Expert Opinion on Therapeutic Targets, Informa Healthcare | AUTOIMMUNITY | Scoop.it
IL-17A-producing CD8+T cells as therapeutic targets in autoimmunity http://t.co/1Mv57xRxd6
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UAB research probes molecular basis of rare genetic disorder - UAB News

UAB research probes molecular basis of rare genetic disorder - UAB News | AUTOIMMUNITY | Scoop.it
Together with European partners, UAB unravels basis of Singleton-Merten Syndrome, which causes heart calcification and early periodontitis. Mary MacDo...
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MDA5 mutations

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Evaluation of B lymphocyte stimulator and a pro...

Evaluation of B lymphocyte stimulator and a pro... | AUTOIMMUNITY | Scoop.it
Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephrit... http://t.co/78vzFQCDny
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Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy -- P...

Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy -- P... | AUTOIMMUNITY | Scoop.it
Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephrit... http://t.co/78vzFQCDny
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On The Evolution Of Immune Response Genes In Plants

On The Evolution Of Immune Response Genes In Plants | AUTOIMMUNITY | Scoop.it
RT @NaturePlants: "On The Evolution Of Immune Response Genes In Plants", about autoimmunity in Arabidopsis hybrids http://t.co/tdDcCh4MDA @…
Gilbert Faure au nom de l'ASSIM's insight:

autoimmunity in plants?

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Infection and autoimmunity in Sjogren's syndrome: a clinical study ... - PubMed - NCBI

J Autoimmun. 2014 Jun;51:17-22. doi: 10.1016/j.jaut.2014.02.008. Epub 2014 Mar 15.
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Proteins likely to trigger psoriasis identified

Proteins likely to trigger psoriasis identified | AUTOIMMUNITY | Scoop.it
Scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world.
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Autoimmunity and tumor immunology: two facets of a probabilistic im... - PubMed - NCBI

BMC Syst Biol. 2014 Nov 11;8(1):120. [Epub ahead of print]
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