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Clinical Immunology | Vol 149, Iss 3, Part A, Pgs 265-356, (December, 2013) | ScienceDirect.com

The online version of Clinical Immunology at ScienceDirect.com, the world's leading platform for high quality peer-reviewed full-text journals.

Via Ellen H Ullman, MSW
Gilbert Faure au nom de l'ASSIM's insight:

survey of clinical trials focusing on immune pathogenesis

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Ellen H Ullman, MSW's curator insight, November 16, 2013 8:52 PM

Current Trials in Type 1 Diabetes

AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert Faure au nom de l'ASSIM
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Autoimmunity

Pathology, Diagnosis and Therapy

Gilbert Faure au nom de l'ASSIM's insight:

Autoimmunity is indeed one of the biggest challenge of Immunology!

Understanding the mechanisms of this physiological immune phenomenon inducing such a diverse array of diseases, joint and muscular, digestive, endocrinological, neurological, cutaneous..

 

Improving the molecular and cellular tools in use for a few decades for diagnosis and follow-up of patients, perhaps screening in the future

Mastering the molecular and cellular therapies to treat patients.

 

You can also find relevant informations on some other topics curated  here such as

Rheumatology http://www.scoop.it/t/rheumatology-rhumatologie

Immunology and biotherapies http://www.scoop.it/t/immunology-and-biotherapies

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HLA-DRB1 and HLA-DQB1 Are Associated with Adult-Onset Immunodeficiency with Acquired Anti-Interferon-Gamma Autoantibodies

HLA-DRB1 and HLA-DQB1 Are Associated with Adult-Onset Immunodeficiency with Acquired Anti-Interferon-Gamma Autoantibodies | AUTOIMMUNITY | Scoop.it
by Manop Pithukpakorn, Ekkapong Roothumnong, Nasikarn Angkasekwinai, Bhoom Suktitipat, Anunchai Assawamakin, Voravich Luangwedchakarn, Pinklow Umrod, Wanna Thongnoppakhun, Suporn Foongladda, Yupin Suputtamongkol Recently a newly identified clinical...
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Association studies of SEPS1 gene polymorphisms with Hashimoto's thyroiditis ... - Nature.com

Association studies of SEPS1 gene polymorphisms with Hashimoto's thyroiditis ...
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Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease | AUTOIMMUNITY | Scoop.it
RT @DrBonnie360: Increase in #leaky gut+#autoimmune related to increase in food additives?http://t.co/MKFp0a3Prx #autoimmunity #crohns http…
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Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. - PubMed - NCBI

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Nat Immunol. 2015 May 25. doi: 10.1038/ni.3175. [Epub ahead of print]
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Antigen-based immunotherapy (AIT) for autoimmune and allergic disease. - PubMed - NCBI

Antigen-based immunotherapy (AIT) for autoimmune and allergic disease. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Curr Opin Pharmacol. 2015 May 21;23:11-16. doi: 10.1016/j.coph.2015.05.003. [Epub ahead of print] REVIEW
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Genes and Immunity - Abstract of article: Suppression of autoimmunity by CD5+ IL-10-producing B cells in lupus-prone mice

Genes and Immunity is a journal dedicated to functional genetics of the immune response.
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Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review

Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review | AUTOIMMUNITY | Scoop.it
RT @Lewis_Lab: "Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review" http://t.co/oyjKhIhAfI
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Aberrant expression of regulatory cytokine IL-35 in patients with systemic lupus erythematosus. - PubMed - NCBI

Aberrant expression of regulatory cytokine IL-35 in patients with systemic lupus erythematosus. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Lupus. 2015 May 11. pii: 0961203315585815. [Epub ahead of print]
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Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome

IntroductionThe lacrimal gland (LG) of the CD25-/- model of Sjögren’s syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines.
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Environmental Basis of Autoimmunity. - PubMed - NCBI

Environmental Basis of Autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Clin Rev Allergy Immunol. 2015 May 22. [Epub ahead of print]
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Psychiatric Autoimmunity: N-Methyl-d-Aspartate Receptor IgG and Beyond. - PubMed - NCBI

Psychiatric Autoimmunity: N-Methyl-d-Aspartate Receptor IgG and Beyond. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Psychosomatics. 2015 May-Jun;56(3):227-41. doi: 10.1016/j.psym.2015.01.003. Epub 2015 Feb 4.
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Circulating IGF-I and IGFBP-3 in relation to the development of β-cell autoimmunity in young children.

Circulating IGF-I and IGFBP-3 in relation to the development of β-cell autoimmunity in young children. | AUTOIMMUNITY | Scoop.it
Authors: Aleksandr Peet, Anu-Maaria Hämäläinen, Pille Kool, Jorma Ilonen, Mikael Knip, Vallo Tillmann, Discipline: Medicine, Type: Journal Article
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Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes

Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes | AUTOIMMUNITY | Scoop.it
Endocrinology Article: Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes...
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Anti-endothelin receptor type a autoantibody in systemic lupus erythematosus associated pulmonary arterial hypertension - Guo - Arthritis & Rheumatology - Wiley Online Library

Anti-endothelin receptor type a autoantibody in systemic lupus erythematosus associated pulmonary arterial hypertension - Guo - Arthritis & Rheumatology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
RT @IMxWatch: Anti-endothelin receptor type A autoantibody in SLE associated PAH #PAH #SLE
http://t.co/HwBwO3GgUK http://t.co/VXBKjCXXOO
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Examination of autoantibody status and clinical features associated with cancer risk and cancer-associated scleroderma. - PubMed - NCBI

Examination of autoantibody status and clinical features associated with cancer risk and cancer-associated scleroderma. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Arthritis Rheumatol. 2015 Apr;67(4):1053-61. doi: 10.1002/art.39022. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study. - PubMed - NCBI

HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Am J Gastroenterol. 2015 May 26. doi: 10.1038/ajg.2015.150. [Epub ahead of print]
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Altered antibody response to vaccination in patients with SLE - Nature.com

Nature.com Altered antibody response to vaccination in patients with SLE Nature.com To characterize the antibody response to foreign antigens in the context of SLE, plasmablasts from patients with this disease (n = 10) or controls (n = 8) were...
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Tpl2 enzyme may be target for treating autoimmune diseases - HealthCanal.com

Tpl2 enzyme may be target for treating autoimmune diseases - HealthCanal.com | AUTOIMMUNITY | Scoop.it
Tpl2 enzyme may be target for treating autoimmune diseases
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The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of ... - Nature.com

Nature.com
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of ...
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Neuroimmunology: an expanding frontier in autoimmunity. - PubMed - NCBI

Neuroimmunology: an expanding frontier in autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Front Immunol. 2015 Apr 29;6:206. doi: 10.3389/fimmu.2015.00206. eCollection 2015. Review
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J&J picks up where Novo left off with an autoimmune licensing deal - FierceBiotech

J&J picks up where Novo left off with an autoimmune licensing deal - FierceBiotech | AUTOIMMUNITY | Scoop.it
Novo Nordisk, gradually exiting the world of autoimmune R&D, has found a home for one of its former projects, handing a development program over to Johnson & Johnson for an undisclosed sum.
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Inflammasomes and human autoimmunity: A comprehensive review

Good summary of #inflammasomes+ #autoimmunity http://t.co/GTJYutXezp http://t.co/jxz3XTPdZc
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The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. - PubMed - NCBI

The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Curr Opin Rheumatol. 2015 May 21. [Epub ahead of print]
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The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. - PubMed - NCBI

The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Immunity. 2015 May 11. pii: S1074-7613(15)00171-5. doi: 10.1016/j.immuni.2015.04.011. [Epub ahead of print]
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Suppression of autoimmunity by CD5 + IL-10-producing B cells in lupus-prone ... - Nature.com

Suppression of autoimmunity by CD5 + IL-10-producing B cells in lupus-prone ...
Nature.com
NKT cells were gated as PBS57-CD1d Tetramer+ TCRβ+CD19− and quantified by flow cytometry. (b) Autoantibody levels in the serum of 8–9-month-old mice.
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