Ashutosh Hospital is portal with information about all the joint related diseases and treatments. The site not only educates you about the joint problems but also provides you details about the best joint replacement surgeons in India.
As the West African Ebola epidemic enters its second year small batches of experimental vaccines are on the cusp of reaching people in the affected countries. Nature magazine tackles the questions that will determine whether vaccines play a role in ending the current epidemic — and can prevent future flare-ups. Two vaccines are leading contenders to be deployed in West Africa early next year. The furthest along is one co-developed by London-based drug firm GlaxoSmithKline (GSK) and the US National Institute for Allergy and Infectious Disease (NIAID) in Bethesda, Maryland. Their vaccine is made of an inactivated chimpanzee cold-causing adenovirus (called ChAd3) that has been engineered to produce an Ebola protein.
Only efficacy trials — slated for next year in Liberia and Sierra Leone — can determine whether a vaccine can prevent Ebola infection. But researchers are scouring data from safety trials to identify the doses and regimens that offer the best chances of working. Those decisions will be made by mid-January, according to Ballou.
One big question is whether the GSK–NIAID vaccine will need to be accompanied with a booster shot (such as the one manufactured by Bavarian Nordic). Monkeys that were protected from Ebola infection by a similar vaccine had received a booster. But a single-shot regimen would be simpler to administer during the current epidemic in West Africa, as well as future Ebola outbreaks.
Adrian Hill, a vaccine scientist at the University of Oxford, UK, who is leading a safety trial of the GSK–NIAID vaccine in the United Kingdom, is a proponent of a booster. Tests of vaccines against other diseases have shown that boosters can drastically increase the levels of infection-battling antibodies and T cells, a type of white blood cell. On 12 December he told a Washington DC conference on Ebola immunology that Bavarian Nordic's booster worked as expected. Fourteen volunteers who got the booster several weeks after their first shot produced higher levels of antibodies within a week (compared with levels in their blood after the first vaccination) and these responses were similar to those seen in monkeys protected from Ebola.
Hill says that a booster might be the only way to get an Ebola vaccine that prevents infection. Others, such as NIAID director Anthony Fauci, argue that a booster shot is important mostly for prolonging vaccine protection and that higher doses of the first shot should be effective in the short term.
The Liberia trial will probably enrol around 30,000 people living in Monrovia. The plan is for volunteers to be randomly assigned to receive either the GSK–NIAID vaccine, the NewLink–Merck vaccine or a saline-solution injection that will serve as a placebo control. But it is unclear how the suspension of the NewLink–Merck safety trial in Geneva will affect those plans. “If that means it is not going forward rapidly for safety reasons, it would impact on plans for the efficacy trial in Liberia,” Hill says. One possibility is to delay this arm of the trial until additional safety tests are completed.
A phase 3 trial of around 6,000 health-care workers in Sierra Leone is also in the planning stages. The current strategy is for all the volunteers to receive a vaccine (yet to be selected) in a phased roll-out. Researchers will determine whether the vaccine works by comparing infection rates among vaccinated and unvaccinated people.
Officials are also discussing the possibility of a third efficacy trial to test whether a strategy known as ring vaccination can quell the epidemic. In this approach, patients living around a newly diagnosed case are vaccinated, in an attempt to prevent transmission.
Pain in the rear or leg that is worse when sittingBurning or tingling down the legWeakness, numbness, or difficulty moving the leg or footA constant pain on one side of the rearA shooting pain that makes it difficult to stand up
Sciatica usually affects only one side of the lower body. Often, the pain extends from the lower back all the way through the back of the thigh and down through the leg. Depending on where the sciatic nerve is affected, the pain may also extend to the foot or toes.
Motion is lotion. Motion helps reduce the risk for osteoarthritis. It both lubricates and nourishes your knees.Camel up. Drink plenty of water. Drying out reduces flexibility and increases wear and tear. On average, you need to drink eight glasses of water (eight ounces each) each day. When you exercise, you will need substantially more water to balance fluid loss."Good" pain. A little discomfort may occur and will lessen after regular exercise. But watch for "bad" pain. Stop if you have more severe, sharp pain, especially if you are limping.Get strong. Do leg lifts that strengthen your quadriceps (front thigh) muscle, which is the main protector of your knee.Warm up, then stretch. Break a light sweat, then stretch to help maintain mobility and reduce joint stiffness.Stay warm. Knees are like barometers and cold, damp weather can make them more symptomatic. Try keeping your knees warm with a neoprene sleeve or knee wrap.Chill out. Ice your knees for 15 minutes after activity or exercise if you tend to develop soreness.Eat for healthy joints. Lose extra pounds to take stress of your knees. Avoid sugary, processed food, as well as foods high in saturated fat, in order to minimize inflammation.
The most common type of arthritis is osteoarthritis, which is a progressive wearing of the cartilage in the knee joint. It occurs more frequently in individuals 50 and older. After 50, the impact of osteoarthritis can worsen due to accumulated use and the wearing down of cartilage that occurs with age. Osteoarthritis of the knee causes pain, limited range of motion, stiffness of the knee, swelling of the joint, tenderness, deformity and weakness.
Causes of osteoarthritis include age, weight, genetics, previous injuries, infections, and illness (such as a tumor or gout). Osteoarthritis can also be caused by sports injuries and wear and tear resulting from physical work in occupations, such as construction and manufacturing.
Neck pain has been around for as long as we can tell. There is mention of neck pain in ancient medical texts from 3500 B.C. and it continues to be a frequent cause of visits to doctors offices. The pain is generally in the back of the neck or along the muscles on the sides of the neck.
We also provide Joint Replacement Services to the patients. These services can be considered as a treatment, when severe joint pain or dysfunction is not alleviated by less-invasive therapies. We are also associated with recognized hospitals from across the country that enables us in offering best solution to you in timely manner.
Elaborating about the patient, whom senior spine and joint replacement surgeon at Gian Sagar Hospital Dr MS Narula, director — spine and joint replacement unit successfully operated, said that the patient said that with the advancements in...
causes of back pain are usually physical, it is important to know that emotional stress can play a role in how severe pain is and how long it lasts.
Dr. Kunal Shah's insight:
Back pain is sometimes linked with pain in the legs, and there may be numbness or a tingling feeling. This is called sciatica. This is due to irritation or squeezing of one of the spinal nerves (called the sciatic nerve). For most people who develop sciatica, the leg pain tends to be the most troublesome symptom and they may not have back pain at all.
The human spine is made up of bones known as vertebrae. These vertebrae are anatomically divided into various regions as cervical (neck region), thoracic (midback), lumbar (lower back), sacral and coccygeal (pelvic region). Most of the fractures that occur due to major car accidents or fall from height affect the thoracic and the lumbar region. Spinal fracture mainly indicates an injury to the vertebrae, but may also affect the nerves, spinal cord, or the ligaments in the spinal column.
No matter how much we fight it as we begin to age, we become more and more susceptible to back problems. This infographic by the Ashutosh Hospital hopes to help educate men and women about back-related health issues so that they know when and where to spot trouble-related areas.
Use recreation methods and regular exercise to prevent unnecessary stress and tension to the neck muscles.Learn stretching exercises for your neck and upper body. Stretch every day, especially before and after exercise. Do it with the help of a physician.If you tend to get neck pain from exercise, apply ice to your neck after physical activity.Use good posture, especially if you sit at a desk all day. Always keep your back supported. Adjust your computer monitor to eye level. This prevents you from one angle view.If you work at a computer, stretch your neck every hour or so.When reading or typing from documents at your desk, place them in a holder at eye level.Assess your sleeping conditions. Make sure your pillow is properly and comfortably supporting your head and neck.
Knee Ligaments Injuries Treatments in India - A ligament is a short band of tough fibrous connective tissue composed mainly of long, stringy collagen molecules
Dr. Kunal Shah's insight:
Knee ligament injuries can cause pain, swelling, tenderness, bruising and reduced movement of your knee. Your knee joint may feel unstable and you may walk with a limp. Treatment of a knee ligament injury can depend on a number of things including which ligament is injured and how sporty and active you are.
Low back pain is one of the most common reasons why adults in North America visit their doctor or miss work. Some estimate that as many as 70% of us will have at least one major episode of debilitating low back pain during their lifetime.
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