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Nanothermometer takes the temperature of living cells and can map millikelvin fluctuations

Nanothermometer takes the temperature of living cells and can map millikelvin fluctuations | ASEM Aquaculture Health | Scoop.it

A tool originally developed for quantum computers can now map temperature changes within a living cell. The technique exploits quantum effects in tiny diamond crystals, or 'nanodiamonds', to detect changes down to a few thousandths of a degree. The researchers were also able to heat selected parts of the cell using a laser. “We now have a tool to control temperature on a cellular level, and we can study how biological systems react to temperature change,” says Peter Maurer, a physicist at Harvard University in Cambridge, Massachusetts, and a member of the team publishing the result recently in Nature.

 

The researchers used a nanowire to inject diamond crystals into a human embryonic cell. They then shone green laser light on the cell, causing the nitrogen impurities to fluoresce with red light.

 

Variations in local temperatures inside the cell affect the intensity of red light emitted by the nitrogen–vacancy centres. The researchers were able to measure that intensity and use it to calculate the temperature of the corresponding nanodiamond. As diamond conducts heat well, the nanocrystal is likely to be the same temperature as its immediate cellular environment.

 

The researchers also injected the cell with gold nanoparticles, then trained a laser on them to heat up different parts of the cell. Thanks to their tiny diamond thermometers, they were able to precisely control where the temperature was rising and by how much.

 

A diamond-based thermometer could be a useful tool in basic biology, Maurer says, noting that a number of biological processes, ranging from gene expression to cellular metabolism, are strongly affected by temperature. For example, biologists could study the development of simple organisms, such as the nematode Caenorhabditis elegans, by controlling temperature locally. “You could heat individual cells and study whether surrounding cells slow down or speed up” their rate of reproduction, Maurer says.

 

Other teams have used fluorescent molecules to map temperature in human cells, but the Harvard thermometer is at least 10 times more sensitive than those techniques, Maurer says, detecting fluctuations of as little as 0.05 Kelvin. The authors say that there is room for improvement, however, because outside of living cells their tiny device has already achieved sensitivities of 0.0018 Kelvin.

 

The nanodiamond thermometers also have potential uses in chemistry to monitor how heat flows affect chemical reactions, especially at the interface between two substances, says David Awschalom, a physicist at the University of California in Santa Barbara, who led one of the earlier studies demonstrating diamond-based thermometry.


Via Dr. Stefan Gruenwald
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This looks as if it could open up some interesting new areas for research

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ASEM Aquaculture Health
Collated articles relevant to the work of the ASEM Aquaculture Platform on Aquatic Animal Health - http://sites.google.com/site/aqasemhealth
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Egypt rocked by tilapia virus scare

Egypt rocked by tilapia virus scare | ASEM Aquaculture Health | Scoop.it
A new virus that has decimated tilapia populations in Ecuador and Israel has now been found in Egypt, according to a new report from WorldFish and the University of Stirling.
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Fish Diseases - 1st Edition

Fish Diseases - 1st Edition | ASEM Aquaculture Health | Scoop.it

Fish Diseases: Prevention and Control Strategies provides information on disease prevention and treatment by some of Newthe most experienced fish culturists in the industry. The book presents both traditional and novel methodologies of identifying and addressing fish disease risk, along with preventative and responsive insights to the challenges impacting fish production today. Both specific (vaccination) and non-specific (immunostimulation) approaches are explored, from maintaining optimal environmental conditions, to understanding how stressors in fish affect their immune system.

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New publication on fish diseases edited by Galina Jeney 
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Gill Health Initiative Meeting 2017

Gill Health Initiative Meeting 2017 | ASEM Aquaculture Health | Scoop.it
The next meeting of the Gill Health Initiative will be in Bergen on April 27-28th 2017
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Abstract submission and conference registration for 18th EAFP conference - EAFP

  Abstract submission and conference registration is now open! 18th International Conference on Diseases of Fish and Shellfish 4th – 8th September 2017, Belfast, Northern Ireland www.eafp2017.com Dear Colleagues, On behalf of the Council of the European Association of Fish Pathologists and the local Organising Committee we invite you to … Read More →
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EAFP Members - time to take action!
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Mycotoxins in Aquaculture [Infographic]

Mycotoxins in Aquaculture [Infographic] | ASEM Aquaculture Health | Scoop.it

Infographic from Biomin showing the most important facts about mycotoxins in aquaculture.

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Highlighting the problem of mycotoxins in aquafeeds
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Solving the $6 billion per year global aquaculture disease problem | Marine Science

A recent Newton Fund Researcher Links workshop on aquatic animal disease gave a group of 50 early career scientists from the UK and Thailand a chance to meet and discuss the biggest issues facing expansion of the global aquaculture industry: disease. The outcome was a focus on developing solutions and new scientific paradigms required to end an era of ‘disease infamy’ in this rapidly expanding global food industry.

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Guide to Using Drugs, Biologics & Other Chemicals in Aquaculture

Guide to Using Drugs, Biologics & Other Chemicals in Aquaculture | ASEM Aquaculture Health | Scoop.it

"All aquaculture operations have occasional demand for drugs, biologics, and other chemicals, collectively referred to as “regulated products”. The Guide to Using Drugs, Biologics, and Other Chemicals in Aquaculture was developed by the Fish Culture Section WGADCB as a comprehensive introduction to the use of regulated products in aquaculture and a resource for fisheries professionals. The Guide includes updated information on aquaculture drugs and contacts for providing feedback. A companion treatment calculator is available in both Excel 97-2003 (.xls) and Excel 2010 (.xlsx) formats. These tools are indispensable for those in need of detailed information regarding the legal and judicious use of these products in aquaculture."

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Updated guide available from AFS-FCS
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H2020 New Call for Access

H2020 New Call for Access | ASEM Aquaculture Health | Scoop.it
The AQUAEXCEL2020 project invites proposals from European research groups for scientific research that utilises the facilities of any of the participating aquaculture research infrastructures. The AQUAEXCEL2020 project unites major aquaculture experimental facilities with capacity to undertake experimental trials on a selection of commercially important fish aquaculture species and system types. These installations are made available to the research community for Transnational Access (TNA) with the support of the European Union’s Horizon 2020 Research and Innovation Programme. Transnational Access involves a research group in one country collaborating with one or more AQUAEXCEL2020 Infrastructures that are located in a different country to the applicant, and which offer facilities and expertise not available in their own country. The facilities available cover the entire range of production systems (cage, pond, recirculation, flowthrough, hatchery and disease challenge); environments (freshwater, marine, cold, temperate and warm water); scales (small, medium and industrial scale); fish species (salmonids, cold and warm water marine fish, freshwater fish and artemia); and fields of expertise (nutrition, physiology, health & welfare, genetics, engineering, monitoring & management technologies). Interested researchers can propose projects that involve visits of one or in some cases two people to the chosen research infrastructure for periods of up to three months. Access to the research infrastructures and associated travel and subsistence expenses will be paid for under the project. The establishment of new transnational collaborations is strongly encouraged, as well as the participation by SMEs.
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The Second Call for AQUAEXCEL Transnational Access Projects is now open with a deadline of 8th July.
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Gent University: INTERNATIONAL TRAINING PROGRAMME ON HEALTH MANAGEMENT IN AQUACULTURE

Gent University: INTERNATIONAL TRAINING PROGRAMME  ON HEALTH MANAGEMENT IN AQUACULTURE | ASEM Aquaculture Health | Scoop.it
19 September - 17 December 2016, Gent University.

The training programme consists of theoretical parts: lectures, case studies, peer-to-peer teaching; and practical parts: wet lab experience (for instance on biofloc operation) and study visits. The lectures, which will include microteaching sessions, will make up the majority of the program. Over a period of 10 weeks, 4 courses will be taught: 

Diseases in Aquaculture by Prof. Peter Bossier & Prof. Annemie Decostere 
Virology by Prof. Hans Nauwynck 
Microbial Community Management by Dr. Peter De Schryver Immunology by Prof. Daisy Vanrompay
 
A number of guest lectures by international authorities is foreseen by Prof. Yoram Avnimelech, Prof. Jorge Galindo-Villegas and Prof. Olav Vadstein.
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MSD Animal Health Hosts Fish Health Workshops

MSD Animal Health Hosts Fish Health Workshops | ASEM Aquaculture Health | Scoop.it
UK - The team from MSD Animal Health, hosted three events across Scotland, to share results of its latest fish health monitoring programmes.
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The Basics of Aquatic Medicine - Webinar

The Basics of Aquatic Medicine - Webinar | ASEM Aquaculture Health | Scoop.it

'Welcome to the 2nd live webinar hosted by WAVMA and IVSA Standing Committee on Veterinary Education (SCoVE)! In this webinar, world leading aquatic medicine specialist Chris Walster will be talking about 'The basics of aquatic medicine' and 'What Vets need to know about fish?'.

 

This unique webinar will provide a fresh insight into the medicine of aquatic species, plus a vets role in the fish world.

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18th March 2016 at 18:00 GMT
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18th March 2016 at 18:00 GMT
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Bacterial Disease is Leading Cause of Mortality in Lumpfish

Bacterial Disease is Leading Cause of Mortality in Lumpfish | ASEM Aquaculture Health | Scoop.it
NORWAY - A new study by the Fisheries and Aquaculture Industry Research Fund (FHF) has identified atypical furunculosis as the "worst offender" of bacterial diseases in lumpfish.
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First Complete Picture of Salmon Gut Bacteria will Help Industry Sustainability

First Complete Picture of Salmon Gut Bacteria will Help Industry Sustainability | ASEM Aquaculture Health | Scoop.it

UK - Researchers from around the world are paving the way for a more ecologically sustainable salmon farming industry with the first complete picture of wild Atlantic salmon gut bacteria.This week, researcher Dr Martin Llewellyn (Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow) and co-workers in Ireland, Scotland, Canada, USA and Wales took a first step towards understanding the role of salmon gut bacteria in salmon health. After two years intensive sampling from adult salmon feeding grounds in West Greenland, returning adults and freshwater juvenile salmon in Canada and Ireland, they have developed the first compete picture of wild Atlantic Salmon gut bacterial diversity across the distribution of the species. The data show that bacterial community composition within the gut was not significantly impacted by geography. Instead life-cycle stage (parr, smolt, adult) strongly defined both the diversity and identity of gut microbial assemblages in the gut, with evidence for community destabilisation in migratory phases. Amongst other observations, Mycoplasmas were recovered in all life-cycle stages in huge abundance, suggesting a potentially vital role for this class of bacteria for gut health. 

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This is a very interesting and developing area of research

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Work on Trà Vinh’s First High-tech Shrimp Breeding Centre Begins

Work on Trà Vinh’s First High-tech Shrimp Breeding Centre Begins | ASEM Aquaculture Health | Scoop.it
VIET NAM - Thông Thuận Group started the construction of a high-tech shrimp breeding centre in the southern Trà Vinh Province’s Trường Long Hòa Commune on Saturday.
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5th Call for Transnational Access Projects | AQUAEXCEL2020

5th Call for Transnational Access Projects | AQUAEXCEL2020 | ASEM Aquaculture Health | Scoop.it
The Fifth Call for Transnational Projects to Access European Aquaculture Research Infrastructures is now open until 17th April 2017.
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Support for small research projects (up to 3 months) at 39 top aquaculture research infrastructures in Europe
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EAFP Workshop announcement - Neglected viral diseases affecting freshwater fish farming - EAFP

EAFP Workshop announcement - Neglected viral diseases affecting freshwater fish farming - EAFP | ASEM Aquaculture Health | Scoop.it
Open EAFP Workshop This open workshop will be organized by Olga Haenen (from WBVR, the Netherlands), Laurent Bigarré (from ANSES, France), Takafumi Ito (from NRIA, Japan), and Niccolò Vendramin (from the EURL for Fish Diseases). This workshop will deal with non-notifiable (but possibly emerging) viruses of farmed freshwater fish, such … Read More →
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Workshop announcement for 18th EAFP conference in Belfast  (4-8 Sept 2017) – "Neglected viral diseases affecting freshwater fish farming"
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Scottish salmon farming's sea lice 'crisis' - BBC News

Scottish salmon farming's sea lice 'crisis' - BBC News | ASEM Aquaculture Health | Scoop.it
The Scottish salmon farming industry is facing major problems from sea lice, which have led to a cut in output and fast rising costs.
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New products and management approaches are being tested or introduced, but so far, sea lice are proving highly resilient and costly!
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New Paradigms to Help Solve the Global Aquaculture Disease Crisis

New Paradigms to Help Solve the Global Aquaculture Disease Crisis | ASEM Aquaculture Health | Scoop.it
Aquatic environments impose a constant and omnipresent risk of pathogen exposure to resident hosts, perhaps even more so than terrestrial systems. Poor knowledge of background microbial diversity in farm systems leads to frequent emergence of previously unknown pathogens, surprising farmers and creating shock in the wider value chain. Scientific (pathology, systematics, diagnostics) and political (trade legislation, listing) responses to emergence are largely reactive and often slow, facilitating local–global transfer of pathogens via trading in live animals and products....

Stentiford GD, Sritunyalucksana K, Flegel TW, Williams BAP, Withyachumnarnkul B, Itsathitphaisarn O, et al. (2017) New Paradigms to Help Solve the Global Aquaculture Disease Crisis. PLoS Pathog 13(2): e1006160. doi:10.1371/journal.ppat.1006160


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Time to stand back and take a more strategic overview...
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The Aquaculturists: 19/07/2016: Benchmark’s new seabass vaccine commences commercial field trials

The Aquaculturists: 19/07/2016: Benchmark’s new seabass vaccine commences commercial field trials | ASEM Aquaculture Health | Scoop.it

Benchmark’s new seabass vaccine for nodavirus commences commercial field trials.


Via Perendale Publishers (Tuti Tan)
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European Association of Fish Pathologists | 2nd Meeting – Stirling September 2016

European Association of Fish Pathologists | 2nd Meeting – Stirling September 2016 | ASEM Aquaculture Health | Scoop.it

Conference topics include: 

Major disease challenges to the salmonid industry 
Major disease challenges to ornamental, cyprinid, shellfish, marine and wild fish industries 
Cleaner fish health
Future technologies and challenges 
Funding opportunities

Use e-mail link on page for further detials. Online registrations via http://shop.stir.ac.uk/browse/product.asp?compid=1&modid=1&catid=27 ;
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Book now for EAFP UK and Ireland meeting in September
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MSc in Aquatic Production and Veterinary Health: City University of Hong Kong

MSc in Aquatic Production and Veterinary Health: City University of Hong Kong | ASEM Aquaculture Health | Scoop.it
City University of Hong Kong’s School of Veterinary Medicine, in collaboration with the University of Stirling (Scotland), will be introducing an MSc in AQUATIC PRODUCTION AND VETERINARY HEALTH in September 2016. The demand for aquatic food worldwide is increasing significantly and at the same time there is pressure for more efficient production and safe food while taking into account the environmental and sustainability issues throughout the entire aquatic food value chain. This programme responds to the large global prevalence of aquatic products and the rising demand in the aquatic industry in Mainland China and Hong Kong. Most aquatic-related master’s programmes in the region approach aquatic production from marine biology, ecology, or environmental perspectives. This MSc programme is differentiated by its focus on aquatic production with a veterinary element, and will attract industry professionals who are seeking to deepen their knowledge in order to advance their careers moving on from production roles into specialist roles.
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With the ongoing development of the aquaculture industry and continual challenge of good health management, this new option in Asia for aquatic heath management training should be of interest to companies and individuals alike.
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Using the H-index to assess disease priorities for salmon aquaculture

Using the H-index to assess disease priorities for salmon aquaculture | ASEM Aquaculture Health | Scoop.it
Preventive Veterinary Medicine Volume 126, 1 April 2016, Pages 199–207

Alexander G. Murraya, Maya Wardehb & K. Marie McIntyreb

Highlights 
• Ranking pathogens of salmon aquaculture is difficult. 
• We use publication trends and H-index to rank pathogens. 
• Sea lice, infectious salmon anaemia, furunculosis have highest H-indices. 
• Bacterial publications in decline, reflects vaccination. 
• Virus and sea lice publications increasing reflecting emerging problems.
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Turbot: The First Vertebrate to be Sequenced in Spain

Turbot: The First Vertebrate to be Sequenced in Spain | ASEM Aquaculture Health | Scoop.it
SPAIN - Scientists from CSIC and the University of Santiago de Compostela have led the field in identifying the genes of turbot which give clues into disease resistance.
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NMBU-researchers have developed new model for vaccine trials in tilapia

NMBU-researchers have developed new model for vaccine trials in tilapia | ASEM Aquaculture Health | Scoop.it
Global intensification of tilapia production has raised questions on its susceptibility to a number of bacterial diseases.  Francisellosis is one of the most devastating tilapia infections and has a troubling impact on the tilapia production.

Researchers at NMBU’s Department of Food Safety and Infection Biology (Matinf) have recently developed a new cohabitation model for vaccine trials in tilapia, and conducted a unique experiment which have never been conducted in Norway before.
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How Norway Avoids Antibiotics in Aquaculture

How Norway Avoids Antibiotics in Aquaculture | ASEM Aquaculture Health | Scoop.it
NORWAY - Over the past few years Norway has cut its antibiotic use in salmon farming to virtually zero. This has led to a flourishing industry and a reduction in the risk of antibiotic resistance in humans.
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The success of vaccines and other health management strategies in reducing the need for antibiotics in salmon farming is well documented, but the headline numbers here are still striking - Norway's salmon farms hold more than double the biomass of the human population whilst antibiotic use is less than 2% of that used for human health in the country.

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