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Rescooped by NCPbiology from Brain Tricks: Belief, Bias, and Blindspots
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Animations of unseeable biology

Animations of unseeable biology | AS Biology | Scoop.it
We have no ways to directly observe molecules and what they do -- Drew Berry wants to change that. In this talk, he shows his scientifically accurate (and entertaining!) animations that help researchers see unseeable processes within our own cells.

(Filmed at TEDxSydney.)

Via David Hall, Jocelyn Stoller
NCPbiology's insight:

Great for DNA replication and mitosis (extension)

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Noroviruses: The Perfect Human Pathogens?

Noroviruses: The Perfect Human Pathogens? | AS Biology | Scoop.it

Noroviruses are perhaps the perfect human pathogens. These viruses possess essentially all of the attributes of an ideal infectious agent: highly contagious, rapidly and prolifically shed, constantly evolving, evoking only limited immunity, and just moderately virulent, allowing most of those infected to fully recover, thereby maintaining a large susceptible pool of hosts. These characteristics have enabled noroviruses to become the leading cause of endemic diarrheal disease across all age groups, the leading cause of foodborne disease, and the cause of half of all gastroenteritis outbreaks worldwide. In the United States alone, noroviruses are responsible for an estimated 21 million cases of acute gastroenteritis annually, including >70,000 hospitalizations and nearly 800 deaths. In developing countries, where the greatest burden of diarrheal disease occurs, noroviruses have been estimated to cause up to 200 000 deaths each year in children <5 years of age. Although recognition of this immense disease burden is relatively recent, it is unclear whether it has long been present and failed to be recognized because of lack of sensitive diagnostics or if, in fact, noroviruses represent a truly emergent public health issue. Regardless, attempts to address the overwhelming burden of norovirus disease first require an understanding of the complexity and efficiency with which these viruses spread.


Via Dr. Stefan Gruenwald
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Interesting extra reading.

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Pathogens in Your Mouth Can Lead to Cancer

Pathogens in Your Mouth Can Lead to Cancer | AS Biology | Scoop.it
Oral pathogens can make their way to distant parts of your anatomy and cause serious problems.

Via Troy Mccomas (troy48)
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Do pathogens act as another risk factor to causing cancer?

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Gum disease bacteria may cause heart disease

Gum disease bacteria may cause heart disease | AS Biology | Scoop.it
Gum disease bacteria may cause heart disease
Medical Xpress
"We report evidence that introduction of oral bacteria into the bloodstream in mice increased risk factors for atherosclerotic heart disease.

Via 27 Heart Disease
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Is there enough evidence to prove causation?

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Researchers engineer bacterium to hunt down and kill pathogens

Researchers engineer bacterium to hunt down and kill pathogens | AS Biology | Scoop.it

Recent examples of new genetic circuits that enable cells to acquire biosynthetic capabilities, such as specific pathogen killing, present an attractive therapeutic application of synthetic biology. A team of researchers in Singapore has developed a technique for bioengineering a bacterium to seek out and kill targeted pathogens.

 

They demonstrate a novel genetic circuit that reprograms Escherichia coli to specifically recognize, migrate toward, and eradicate both dispersed and biofilm-encased pathogenic Pseudomonas aeruginosa cells. The reprogrammed E. coli degraded the mature biofilm matrix and killed the latent cells encapsulated within by expressing and secreting the antimicrobial peptide microcin S and the nuclease DNaseI upon the detection of quorum sensing molecules naturally secreted by P. aeruginosa. Furthermore, the reprogrammed E. coli exhibited directed motility toward the pathogen through regulated expression of CheZ in response to the quorum sensing molecules.

 

By integrating the pathogen-directed motility with the dual antimicrobial activity in E. coli, we achieved signifincantly improved killing activity against planktonic and mature biofilm cells due to target localization, thus creating an active pathogen seeking killer E. coli.


Via Dr. Stefan Gruenwald
NCPbiology's insight:

Interesting extra reading?

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Biology Animations Sitemap

Biology Animations and Still-graphics

Via Gabe Kraljevic
NCPbiology's insight:

Useful animations for a variety of topics

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Gabe Kraljevic's curator insight, January 30, 2013 3:57 PM

Some great animations of some complicated biological processes:  DNA coiling, mitosis, replication, etc.