This research investigates the relationship between students’ field of study and their preference for distance education. For this research, data were used from the National Postsecondary Student Aid Study: Undergraduate, which uses a complex survey design to collect data from a nationally representative sample of undergraduate postsecondary students in the US. Results show that a student’s field of study is significantly related to enrollment in distance education classes, enrollment in a distance education program, and satisfaction with distance education. Full-time employment, presence of dependents, and a mobility-limiting disability are also significantly associated with distance education preference. Enrollment trends show significant growth in distance education enrollment over 2000 to 2008 among students in all fields of study.