Background: Many of the well-studied prognostic factors for patients with breast cancer (BC) brain metastases (BM) are based on data from an era when stereotactic radiosurgery (SRS) was not commonly used. In this study, we examined patient characteristics and outcomes for patients with CNS metastases who recently underwent cranial radiation at MSKCC. Methods: 173 consecutive BC patients with CNS metastases receiving SRS or WBRT from January 2009 to December 2011 were identified. Clinico-pathologic and treatment information was obtained by retrospective review. Patient characteristics and associations were evaluated. Time from BM to death was evaluated by Kaplan-Meier and log-rank tests. Results: Of 173 patients (2 missing HER2 status), the subgroups were: HR+HER2-: 77 (45%), HR+HER2+: 28 (16%), HR-HER2+: 17(10%), and HR-HER2-(TNBC): 49 (29%). 121 had whole brain radiotherapy (4 with prior SRS), and 50 had SRS only. The use of SRS differed by subtype (overall Fisher’s exact p=0.02): 59% (HR-HER2+), 33% (TNBC), 29% (HR+HER2+), 21% (HR+HER2-). There were a total of 110 deaths. The median follow-up for survivors was 19mo (range: 6-67mo). The median time from BM to death for all patients was 17.5mo (95% confidence interval: 14-20mo): 41mo (HR-HER2+), 63mo (HR+HER2+), 14.5mo (HR+HER2-), 14mo (TNBC; log-rank test p=0.0001).
United Nations report: US 17th happiest country in the world CBS News Can living in America put a smile on your face? A new United Nations report on happiness shows that the U.S. ranks 17th out of 156 countries.
In The Wall Street Journal, Kirk McDonald writes that college graduates without basic computer programming skills are shortchanging their career choices.
In part, it's not your fault. If you grew up and went to school in the United States, you were educated in a system that has eight times as many high-school football teams as high schools that teach advanced placement computer-science classes. Read more...
"As I head into the new school year, I'm not scrambling for my old lesson plan book or looking for notes in some long buried folder. All of my work is saved in Evernote and I will be sharing the work with my students on the second day of school. As I was sitting and thinking about all of the things I was going to need to start the year, I was struck by the number of things I will not need now that I'm as paperless as I can get. In no particular order, here are the things I will not miss in the upcoming school year."
Although these were designed specifically for GIS day during Geography Awareness Week, these 2 excellent map-based treasure hunts from ESRI are great any time of year. The answer to the question will only pop up in you are zoomed in the the right region (SHIFT + Make a box = Zoom to area). These links will take you to the World Cities quiz and also to the Mountains quiz.
Sharing your scoops to your social media accounts is a must to distribute your curated content. Not only will it drive traffic and leads through your content, but it will help show your expertise with your followers.
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Integrating your curated content to your website or blog will allow you to increase your website visitors’ engagement, boost SEO and acquire new visitors. By redirecting your social media traffic to your website, Scoop.it will also help you generate more qualified traffic and leads from your curation work.
Distributing your curated content through a newsletter is a great way to nurture and engage your email subscribers will developing your traffic and visibility.
Creating engaging newsletters with your curated content is really easy.