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A Tale of Two Medicines
Natural Medicine, Pharmaceuticals and GMO’s, the Good, the Bad and the OMG! - (The information provided is not intended to be a substitute for professional medical advice, diagnosis or treatment. Never disregard professional medical advice, or delay in seeking it, because of something you have read on this scoopit page.)
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FDA Regulates Internet Search - Forbes

FDA Regulates Internet Search - Forbes | A Tale of Two Medicines | Scoop.it

The Food and Drug Administration wants to regulate Internet search.

At the least, searches that are mediated by regulated medical companies, and tie disease keywords to specific, regulated medical products.

 

The issue has come to the fore in a warning letter that FDA recently sent to Medical Doctors Research (MDR), a Florida-based researcher and manufacturer of nutritional supplements.

 

In the January 29th letter, FDA alleges a number of problems with MDR’s manufacturing and promotional activities. But the one that’s catching attention is the FDA’s beef with MDR’s website.

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Plant extract for diabetes: eight times more potent than the standard anti-diabetic drug Acarbose.

Plant extract for diabetes: eight times more potent than the standard anti-diabetic drug Acarbose. | A Tale of Two Medicines | Scoop.it

A group of researchers from the university’s School of Science, led by Dr Solomon Habtemariam, believe they have identified potential sources of medicines derived from plants which may have fewer adverse side-effects for diabetes sufferers.

 

The scientists are investigating the properties of two plants found in south-east Asia which they think could have properties that are not only anti-diabetic, but also lipid- or fat-lowering, and so can help tackle obesity.

 

Dr Habtemariam, a leading expert on drug discovery research from natural sources, says the work could prove a crucial breakthrough in the treatment of diabetes, which he describes a “growing global epidemic”.

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A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer ...

Recently, we identified Corilagin as a major active component with anti-tumor activity in this herbal medicine. Corilagin is a member of the tannin family that has been discovered in many medicinal plants and has been used as an anti-inflammatory agent.

However, there have been few reports of the anti-tumor effects of Corilagin, and its anti-tumor mechanism has not been investigated clearly. The aim of the present study is to investigate the anticancer properties of Corilagin in ovarian cancer cells.

Methods: The ovarian cancer cell lines SKOv3ip, Hey and HO-8910PM were treated with Corilagin and analyzed by Sulforhodamine B (SRB) cell proliferation assay, flow cytometry, and reverse phase protein array (RPPA).

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UNMC study suggests vitamin D could reduce lung inflammation

UNMC study suggests vitamin D could reduce lung inflammation | A Tale of Two Medicines | Scoop.it

Results of a University of Nebraska Medical Center research study suggest that vitamin D may be important for humans exposed to agricultural organic dust. In the study, researchers found a significant decrease in lung inflammation in mice exposed to hog barn dust that received high doses of vitamin D.

 

“We found that the relatively high vitamin D treatment group had significantly decreased lung inflammation. The mice still got inflammation but didn’t get it as bad,” said Jill Poole, M.D., associate professor in the UNMC Department of Internal Medicine and principal investigator of the study.

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What Really Causes Kidney Stones (And Why Vitamin C Does Not)

A recent widely-publicized study claimed that vitamin C supplements increased the risk of developing kidney stones by nearly a factor of two.[1] The study stated that the stones were most likely formed from calcium oxalate, which can be formed in the presence of vitamin C (ascorbate), but it did not analyze the kidney stones of participants. Instead, it relied on a different study of kidney stones where ascorbate was not tested. This type of poorly organized study does not help the medical profession or the public, but instead causes confusion.

 

The study followed 23,355 Swedish men for a decade. They were divided into two groups, one that did not take any supplements (22,448), and another that took supplements of vitamin C (907). The average diet for each group was tabulated, but not in much detail. Then the participants who got kidney stones in each group were tabulated, and the group that took vitamin C appeared to have a greater risk of kidney stones. The extra risk of kidney stones from ascorbate presented in the study is very low, 147 per 100,000 person-years, or only 0.15% per year.

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Jack Andraka, the Teen Prodigy of Pancreatic Cancer

Jack Andraka, the Teen Prodigy of Pancreatic Cancer | A Tale of Two Medicines | Scoop.it

The silver glint of a retainer: Andraka grins. Since he won the $75,000 grand prize at this past spring’s Intel International Science and Engineering Fair, one of the few freshman ever to do so, he’s become a North County High School celebrity to rival any soccer star or homecoming queen. A series of jokes ensue about Andraka’s mad scientist doings in the school’s imaginary “dungeon” laboratory. In reality, Andraka created his potentially revolutionary pancreatic cancer detection tool at nearby Johns Hopkins University, though he does sometimes tinker in a small basement lab at the family’s house in leafy Crownsville, Maryland, where a homemade particle accelerator crowds the foosball table.

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Exposure to pesticides increases type-2 diabetes risk

Exposure to pesticides increases type-2 diabetes risk | A Tale of Two Medicines | Scoop.it

Regardless of a person’s age, gender or body mass index, pesticides in food, air and water may be directly linked with the development of type 2 diabetes.

 

Persistent Organic Pollutants (POPs) like pesticides tend to concentrate in body fat, and they might be one of the reasons why obese people are more likely to develop diabetes, since the more fat the higher the POP concentrations in the body.

 

In a paper recently published in the journal Environmental Research, Spanish researchers analysed the concentrations of a specific group of POPs in the adipose tissue of 386 adults.

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What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations?

What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations? | A Tale of Two Medicines | Scoop.it

There have been renewed interests in natural products as drug discovery sources. In particular, natural product combinations have been extensively studied, clinically tested, and widely used in traditional, folk and alternative medicines. But opinions about their therapeutic efficacies vary from placebo to synergistic effects. The important questions are whether synergistic effects can sufficiently elevate therapeutic potencies to drug levels, and by what mechanisms and at what odds such combinations can be assembled. We studied these questions by analyzing literature-reported cell-based potencies of 190 approved anticancer and antimicrobial drugs, 1378 anticancer and antimicrobial natural products, 99 natural product extracts, 124 synergistic natural product combinations, and 122 molecular interaction profiles of the 19 natural product combinations with collective potency enhanced to drug level or by >10-fold. Most of the evaluated natural products and combinations are sub-potent to drugs. Sub-potent natural products can be assembled into combinations of drug level potency at low probabilities by distinguished multi-target modes modulating primary targets, their regulators and effectors, and intracellular bioavailability of the active natural products.

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Organic Farming Improves Pollination Success in Strawberries

Organic Farming Improves Pollination Success in Strawberries | A Tale of Two Medicines | Scoop.it

Pollination of insect pollinated crops has been found to be correlated to pollinator abundance and diversity. Since organic farming has the potential to mitigate negative effects of agricultural intensification on biodiversity, it may also benefit crop pollination, but direct evidence of this is scant. We evaluated the effect of organic farming on pollination of strawberry plants focusing on (1) if pollination success was higher on organic farms compared to conventional farms, and (2) if there was a time lag from conversion to organic farming until an effect was manifested. We found that pollination success and the proportion of fully pollinated berries were higher on organic compared to conventional farms and this difference was already evident 2–4 years after conversion to organic farming. Our results suggest that conversion to organic farming may rapidly increase pollination success and hence benefit the ecosystem service of crop pollination regarding both yield quantity and quality.

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Commonly prescribed antibiotics ineffective for treating bronchitis.

Commonly prescribed antibiotics ineffective for treating bronchitis. | A Tale of Two Medicines | Scoop.it

The antibiotic amoxicillin, that doctors typically prescribe for common lower respiratory tract infections (LRTI) such as bronchitis, is no more effective at relieving symptoms than the use of no medication, even in older patients. The findings are from the largest randomised placebo controlled trial of antibiotics for acute uncomplicated LRTI to date, which was led by the University of Southampton and published Online First in The Lancet Infectious Diseases.

“Patients given amoxicillin don’t recover much quicker or have significantly fewer symptoms," explains Paul Little, Professor of Primary Care Research at the University of Southampton.

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Monsanto Lawyer Suggests New Standard For Suing Farmers : NPR

Monsanto Lawyer Suggests New Standard For Suing Farmers : NPR | A Tale of Two Medicines | Scoop.it

For years, the biotech giant Monsanto has provoked outrage among its critics for suing farmers who save and replant seeds, such as soybeans and canola, from the company's patented Roundup Ready crops.

 

Some of that outrage is based on a decade-old case in Canada, in which a court ruled that a farmer, Percy Schmeiser, violated Monsanto's patents by planting canola that he "knew or ought to have known" contained Monsanto's Roundup Ready gene. Schmeiser argued that he didn't want the gene in his fields, and that it had become incorporated into his canola via wind-blown pollen

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Report: Death by Medicine

Report: Death by Medicine | A Tale of Two Medicines | Scoop.it

This fully referenced report shows the number of people having in-hospital, adverse reactions to prescribed drugs to be 2.2 million annually. The number of unnecessary antibiotics prescribed for viral infections is 20 million per year. The number of unnecessary medical and surgical procedures performed is 7.5 million per year. The number of people exposed to unnecessary hospitalization is 8.9 million per year.

 

The most stunning statistic, however, is that the total number of deaths caused by conventional medicine is nearly 800,000 per year. It is now evident that the American medical system is the leading cause of death and injury in the US. By contrast, the number of deaths attributable to heart disease in 2001 was 699,697, while the number of deaths attributable to cancer was 553,251

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Phytocannabinoids beyond the Cannabis plant – do they exist?

Phytocannabinoids beyond the Cannabis plant – do they exist? | A Tale of Two Medicines | Scoop.it

It is intriguing that during human cultural evolution man has detected plant natural products that appear to target key protein receptors of important physiological systems rather selectively. Plants containing such secondary metabolites usually belong to unique chemotaxa, induce potent pharmacological effects and have typically been used for recreational and medicinal purposes or as poisons. Cannabis sativa L. has a long history as a medicinal plant and was fundamental in the discovery of the endocannabinoid system. The major psychoactive Cannabis constituent Δ9-tetrahydrocannabinol (Δ9-THC) potently activates the G-protein-coupled cannabinoid receptor CB1 and also modulates the cannabinoid receptor CB2. In the last few years, several other non-cannabinoid plant constituents have been reported to bind to and functionally interact with CB receptors. Moreover, certain plant natural products, from both Cannabis and other plants, also target other proteins of the endocannabinoid system, such as hydrolytic enzymes that control endocannabinoid levels. In this commentary we summarize and critically discuss recent findings.

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IV vitamin C doubles survival time of pancreatic cancer patients in new clinical trial

IV vitamin C doubles survival time of pancreatic cancer patients in new clinical trial | A Tale of Two Medicines | Scoop.it

A small Phase I clinical trial in the U.S. has just shown that adding IV (intravenous) vitamin C to a common chemo drug for pancreatic cancer extended patients' average survival time to 12 months, compared to historical survival times of 5.65 months for such patients. More remarkable is that three of the patients were still alive at the end of the trial (two at 15 months, one at 29 months survival time) which means overall survival could further increase.

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US farmers may stop planting GMs after poor global yields.

US farmers may stop planting GMs after poor global yields. | A Tale of Two Medicines | Scoop.it

Some US farmers are considering returning to conventional seed after increased pest resistance and crop failures meant GM crops saw smaller yields globally than their non-GM counterparts.


Farmers in the USA pay about an extra $100 per acre for GM seed, and many are questioning whether they will continue to see benefits from using GMs.

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Antiproliferative activity of Alpinia officinarum extract in the human breast cancer cell line MCF-7

Alpinia officinarum (A. officinarum), a member of the ginger family, is used in traditional medicine to treat stomach ache, cold and swelling. Previous studies have demonstrated an anticancer effect of the A. officinarum extract and its major components in several cancer cell lines. However, the molecular mechanisms underlying the activity of this extract in breast cancer cells have not been fully elucidated to date. The aim of the present study was to investigate the molecular mechanisms underlying the activity of a methanolic extract of A. officinarum, by examining its effects on the proliferation of the breast cancer cell line MCF-7. Notably, the extract inhibited MCF-7 cell proliferation in a dose- and time‑dependent manner.

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Questioning the CDC 36,000 Deaths from Seasonal Flu Figure

Questioning the CDC 36,000 Deaths from Seasonal Flu Figure | A Tale of Two Medicines | Scoop.it

The fact is the 36,000 number of deaths is really an estimate and not an exact number as often it is represented.  More importantly it is a mathematical estimate based on an assumption that if a death certificate had “respiratory or circulatory disease” listed as a cause of death that it should be counted as a “flu-related” death.

Just how many deaths are directly associated with the flu?  According to Peter Doshi in the British Medical Journal:

‘… according to the CDC's National Center for Health Statistics (NCHS), “influenza and pneumonia” took 62,034 lives in 2001 - 61,777 of which were attributed to pneumonia and 257 to flu, and in only 18 cases was flu virus positively identified.  Between 1979 and 2002, NCHS data show an average 1348 flu deaths per year (range 257 to 3006).’

Jonathan Middleton's insight:

This is an old story from 2009 but well worth dragging into the now.

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Scientists Point Out Corruption in Vaccine's Promotion

Scientists Point Out Corruption in Vaccine's Promotion | A Tale of Two Medicines | Scoop.it

Researchers are speaking out about the corruption in science with regard to vaccines. Certainly, they're in the minority, but their expertise and solid evidence for their claims are resulting in both their studies and their concerns being published in medical journals.

 

The arena of vaccination, which has been adversely affecting so many children, is now a centerpoint for documenting how Big Pharma has taken over so much of science, resulting in outright fraud that's used to promote their products. Scientists Lucija Tomljenovic, Christopher A. Shaw, Judy Wilyman, Eva Vanamee, and Toni Bark use the example of Merck's Gardasil, a human papilloma virus (HPV) vaccine, to demonstrate the point that HPV vaccine activism is not based on science, but instead on misrepresentations of science.

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Vaccine hazards – what the UK government hid and ignored

Vaccine hazards – what the UK government hid and ignored | A Tale of Two Medicines | Scoop.it

It never rains but it pours and in the last couple of weeks we have found ourselves in the middle of a deluge of news stories about childhood vaccinations.

 

Perhaps as a result, an extraordinary paper, published by a respected medical researcher, which dishes the dirt on 30 years of secret official transcripts, has resurfaced. For those that missed it the first time it is a real eye opener.

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Top environmentalist converts on GMO

Top environmentalist converts on GMO | A Tale of Two Medicines | Scoop.it
By Cindy National Corn Growers Association A leading environmental activist and critic of genetically modified food recently announced the error of his ways and his conversion to being a supporter ...
Jonathan Middleton's insight:

Another sell out comes forward.

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Natural medicine demystifies cancer, says Ayodele

Natural medicine demystifies cancer, says Ayodele | A Tale of Two Medicines | Scoop.it

A frontline Naturopath, and Herbal Medicine practitioner Dr. Isaac Ayodele, has called for greater emphasis on consideration of natural medicine in the  management treatment of cancer in Nigeria.

 

Ayodele, who is CEO, Ayodele Slimmers and Naturopathic Clinic,  and Chairman, Boad of Trustees, BOT, Natural Integrative Medicine Association, NIMPA, declared:  “There is no big deal in cancer. It is not a death sentence but coined to impose fear. The fear of cancer has killed more than the ailment.”

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Omega-3 Fatty Acid and Epilepsy - A recent, small study suggests EPA could reduce seizure activity in people with epilepsy

Omega-3 Fatty Acid and Epilepsy - A recent, small study suggests EPA could reduce seizure activity in people with epilepsy | A Tale of Two Medicines | Scoop.it

Six out of 10 patients recorded a reduction of seizures in response to EPA supplementation (12–59% when compared to baseline). One patient experienced reduced severity and shortened duration, in spite of a reported increase in seizure incidence. Overall, subjects experienced a non-significant 16% reduction in total seizure activity, compared to baseline.

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Banana Peel is Capable of Absorbing the Pesticides Atrazine and Ametryne from River and Treated Waters with a 90% Removal Efficiency.

Banana Peel is Capable of Absorbing the Pesticides Atrazine and Ametryne from River and Treated Waters with a 90% Removal Efficiency. | A Tale of Two Medicines | Scoop.it

The feasibility of using banana peel for removal of the pesticides atrazine and ametryne from river and treated waters has been demonstrated, allowing the design of an efficient, fast, and low-cost strategy for remediation of polluted waters. The conditions for removal of these pesticides in a laboratory scale were optimized as sample volume = 50 mL, banana mass = 3.0 g, stirring time = 40 min, and no pH adjustment necessary. KF(sor) values for atrazine and ametryne were evaluated as 35.8 and 54.1 μg g–1 (μL mL–1) by using liquid scintillation spectrometry.

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Vitamin K2: The Missing Nutrient May Reduce The Risk Of Prostate Cancer By 35%.

Vitamin K2: The Missing Nutrient May Reduce The Risk Of Prostate Cancer By 35%. | A Tale of Two Medicines | Scoop.it

A study recently published by the European Prospective Investigation into Cancer and Nutrition (EPIC)has revealed that increased intake of vitamin K2 may reduce the risk of prostate cancer by 35 percent. The authors point out that the benefits of K2 were most pronounced for advanced prostate cancer, and, importantly, that vitamin K1 did not offer any prostate benefits.

 

The findings were based on data from more than 11,000 men taking part in the EPIC Heidelberg cohort. It adds to a small but fast-growing body of science supporting the potential health benefits of vitamin K2 for bone, cardiovascular, skin, brain, and now prostate health.

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Matcha Green Tea Contains 137x Antioxidants of Standard Green Tea says Vitalife Teas

Matcha Green Tea Contains 137x Antioxidants of Standard Green Tea says Vitalife Teas | A Tale of Two Medicines | Scoop.it
The University of Colorado discovered, in the Journal of Chromatography 2003, that matcha green tea (a powdered version of green tea - as sold by Vitalife Teas) contains 137x the antioxidant EGCG compared to traditional steeped-leaf green teas -...
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