Cannabidiol (CBD) seems to carry less of a stigma than tetrahydrocannabinol (THC), a psychoactive cannabinoid that is credited with the “high” associated with cannabis, and shows promise as a way to treat a variety of cancers. In turn, CBD has received a great deal of attention in recent years.
Now, a team of researchers from Italy and the UK report that cannabis extracts high in cannabidiol (CBD) can help prevent the genesis and spread of colon cancer in mice. Their study was published in Phytomedicine December 27.
According to their results, a “botanical drug substance” (BDS) with high levels of cannabidiol (CBD) inhibited the growth of tumor cells, but not healthy ones. The researchers determined that this action was mediated by activation of the cells’ CB1 and CB2 receptors.
Also investigated in the study was the effect of pure cannabidiol (CBD) on colon cancer. According to the data collected, pure CBD inhibited tumor growth also. Interestingly, it did so through activation of the CB1 receptors only.