Alternatives and refinements to animal research
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Alternatives and refinements to animal research
News about the replacement and reduction of animals in scientific research, and improvements in welfare practice.
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Nature jobs: Making the transition to computational research

Nature jobs: Making the transition to computational research | Alternatives and refinements to animal research | Scoop.it
Biologists frustrated with wet-lab work can find rewards in a move to computational research.

Via Mary Williams
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NC3Rs - £1.26m committed for postgraduate training to reduce and refine animal use in research

NC3Rs - £1.26m committed for postgraduate training to reduce and refine animal use in research | Alternatives and refinements to animal research | Scoop.it
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BASF receives 2013 Animal Protection Research Prize

BASF receives 2013 Animal Protection Research Prize | Alternatives and refinements to animal research | Scoop.it
For developing animal-free testing methods for skin sensitisation, as well as eye and skin irritation (Researchers win prize for their work aiming to reduce & replace animal experimentation @BMELV http://t.co/iatiA5KXVT)...
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NC3Rs - 2013 Research Review

NC3Rs - 2013 Research Review | Alternatives and refinements to animal research | Scoop.it
National Centre for the 3Rs - Pioneering Better Science's insight:

#3Rs research spotlight: 3D tumour models provide high throughput screening tool for the development of cancer drugs 

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Pioneering better science through research funding | NC3Rs blog

Pioneering better science through research funding | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it
National Centre for the 3Rs - Pioneering Better Science's insight:

Delivering genuine and sustained progress in the 3Rs is primarily dependent upon scientific discovery and technological innovation. Research funding is essential. 

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Getting the measure of replacement, reduction and refinement | NC3Rs blog

Getting the measure of replacement, reduction and refinement | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it
National Centre for the 3Rs - Pioneering Better Science's insight:

Science is full of measurements but, ironically, one of the most difficult things to measure accurately is the growth of science itself, and the impact it has on human and animal lives and behaviour...

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3-D printers could become research animals' best friends

3-D printers could become research animals' best friends | Alternatives and refinements to animal research | Scoop.it
Alan Faulkner-Jones, a bioengineering PhD student at the University of Edinburgh, believes 3-D printed human cells could eliminate the use of live animals to test drugs within five years, and with more potential accuracy to boot.
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NC3Rs - NC3Rs makes a commitment to public engagement with research

National Centre for the 3Rs - Pioneering Better Science's insight:

"The NC3Rs is now funding a diverse portfolio of inspiring science through a thriving cross-discipline community of researchers up and down the country. This critical mass of research provides us with a unique opportunity to better inform ongoing dialogue on animal research with cutting-edge technologies and approaches as alternatives to animals, along with significant improvements to animal care and handling. By applying the 3Rs, often improved scientific approaches not only benefit animals, but go a long way to further our understanding of health and disease, and can easily illustrate the 3Rs as a working scientific methodology."

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How and why do we use animals in research? - New Statesman

How and why do we use animals in research? - New Statesman | Alternatives and refinements to animal research | Scoop.it
How and why do we use animals in research?
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Is poor reporting of animal research hindering scientific progress? | NC3Rs blog

Is poor reporting of animal research hindering scientific progress? | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it
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AstraZeneca, Wyss Institute To Develop Animal Organs-on-Chips - Drug Discovery & Development

AstraZeneca, Wyss Institute To Develop Animal Organs-on-Chips - Drug Discovery & Development | Alternatives and refinements to animal research | Scoop.it
Drug Discovery & Development AstraZeneca, Wyss Institute To Develop Animal Organs-on-Chips Drug Discovery & Development "Comparing human and animal Organs-on-Chips is an exciting example of what we call 'predictive science,' in which we harness the...
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Improving welfare practice in rodent studies of fatigue | NC3Rs blog

Improving welfare practice in rodent studies of fatigue | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it

Previously a laboratory animal veterinarian, NC3Rs David Sainsbury Fellow Dr Claire Richardson is now working to improve the welfare of mice used in chronic liver disease research. 

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Bristol University | News from the University | School of Veterinary Sciences

Bristol University | News from the University | School of Veterinary Sciences | Alternatives and refinements to animal research | Scoop.it
New research, carried out in collaboration between the University of Bristol’s School of Veterinary Sciences and AstraZeneca Brixham Environmental Laboratory, could improve the welfare standards of millions of fish used by scientists around the...
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A bioreactor to predict the efficacy of antifungal therapies | NC3Rs blog

National Centre for the 3Rs - Pioneering Better Science's insight:

"Our dynamic in vitro model of the human alveolus can be used to study the pharmacokinetics and pharmacodynamics of antifungal agents. It has reduced mouse use in my laboratory alone 2,000 animals per year.”

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Call for CCTV to monitor welfare of lab animals | The Times

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Novo Nordisk Honors Employees Who Improve the Lives of Research Animals - 3BL Media (press release)

Novo Nordisk Honors Employees Who Improve the Lives of Research Animals - 3BL Media (press release) | Alternatives and refinements to animal research | Scoop.it
Novo Nordisk Honors Employees Who Improve the Lives of Research Animals 3BL Media (press release) The judges based their decision on a number of criteria such as global applicability, number of animals affected, ingenuity, simplicity and “simply...
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When Mice Mislead

National Centre for the 3Rs - Pioneering Better Science's insight:

An article in Science discusses the translation of animal studies into human studies and urges researchers to have stricter safeguards and better statistics to ensure their science is solid

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Futuristic “Human-on-Chip” Models Will Help Drug Development | Xconomy

Futuristic “Human-on-Chip” Models Will Help Drug Development | Xconomy | Alternatives and refinements to animal research | Scoop.it
The pharmaceutical industry needs better scientific models for testing drugs before they get to the proving ground of human clinical trials. Current lab di
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“Human lung” model developed to replace animal testing

“Human lung” model developed to replace animal testing | Alternatives and refinements to animal research | Scoop.it
Researchers at a Welsh university have developed a human tissue model of the lung which can be used to detect the toxicity of cosmetics to humans without the need for animal testing.
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Maximising the potential of the 3Rs

National Centre for the 3Rs - Pioneering Better Science's insight:

The ethics of animal research are not a black and white issue. Between the nothing goes and the anything goes there are at least 50 shades of grey. The common ground across these shades is the 3Rs principles of replacement, reduction and refinement. Taking an evidence-based approach to the 3Rs brings objectivity to the debate and acts as a catalyst for change. Most importantly, it can lead to better science and business, which should be everyone’s mutual goal.

- See more at: http://blog.nc3rs.org.uk/maximising-the-potential-of-the-3rs/#sthash.Oun3d0l0.dpuf

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3Rs Prize 2013 open for nominations

3Rs Prize 2013 open for nominations | Alternatives and refinements to animal research | Scoop.it
International prize for excellence champions the 3Rs globally
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NC3Rs - Important breakthrough in identifying the effect of epilepsy treatment

NC3Rs - Important breakthrough in identifying the effect of epilepsy treatment | Alternatives and refinements to animal research | Scoop.it

Social amoeba used to identify molecular mechanism by which valproate blocks seizures in the brain

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Scientists Find a Way to Reduce Fish and Animal Usage in Experiments by ... - Science World Report

Scientists Find a Way to Reduce Fish and Animal Usage in Experiments by ... - Science World Report | Alternatives and refinements to animal research | Scoop.it

Scientists have found a new way to cut the use of fish and other animals to test the toxicity of natural and man-made chemicals by using cells from the gills and liver of the rainbow trout fish.


Via Global Aqua Link
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NC3Rs - Experimental design and statistical analysis

NC3Rs - Experimental design and statistical analysis | Alternatives and refinements to animal research | Scoop.it
Appropriate experimental design & statistical analysis techniques - key to minimise the use of animals in research http://t.co/YQZESiSVGd
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Inside the mouse house: animal testing in Irish labs

Inside the mouse house: animal testing in Irish labs | Alternatives and refinements to animal research | Scoop.it
Animals are used all the time for research in Ireland but scientists are split about whether or not to talk openly about it
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