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Innovations with 3Rs benefits in The Scientist Top 10 | NC3Rs blog

National Centre for the 3Rs - Pioneering Better Science's insight:

This month The Scientist magazine announced the winners of their annual Top 10 Innovations 2013 competition, which highlights the best global technologies to enter the lab. Three of these have potential to replace, reduce or refine the use of animals in research and the NC3Rs’ Technology Programme Manager, Dr Anthony Holmes, gives his own verdict on each one.

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Alternatives and refinements to animal research
News about the replacement and reduction of animals in scientific research, and improvements in welfare practice.
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Scooped by National Centre for the 3Rs - Pioneering Better Science
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Mini-liver research to reduce animal use in science - YouTube

Research that has for the first time successfully grown "mini-livers" from adult mouse stem cells has won the UK's international prize for the scientific and...
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Collaborative effort to reduce animal use and share best practise in ageing research | NC3Rs blog

Collaborative effort to reduce animal use and share best practise in ageing research | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it

A new facility called ShARM (Shared Ageing Research Models) is bringing together researchers working on mouse models of ageing, with the aim of improving scientific practice by encouraging both resource and data sharing and by creating a new forum for discussion about animal welfare issues. Ilaria Bellantuono and Adele Duran from ShARM offer further explanation...

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Research Council Celebrates 20 Years of Animal Welfare Advances

Research Council Celebrates 20 Years of Animal Welfare Advances | Alternatives and refinements to animal research | Scoop.it
UK - BBSRC has supported world-leading bioscience for over two decades. For its 20th anniversary, the Research Council will be exploring a variety of ways that BBSRC helps to deliver impact from research, focusing here on animal welfare.
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'Virtual fish' research aims to reduce the requirement for live animal testing

'Virtual fish' research aims to reduce the requirement for live animal testing | Alternatives and refinements to animal research | Scoop.it
#3Rs MT @PlymUni: 'Virtual fish' research aims to reduce the requirement for live animal testing http://t.co/bn90nASJ48
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Taking inspiration from human orthopaedics to improve research with monkeys | NC3Rs blog

Taking inspiration from human orthopaedics to improve research with monkeys | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it

A redesigned device for recording brain activity in monkeys, which is less prone to infection than standard systems, has been recognised by the NC3Rs 3Rs Prize for its potential to improve the welfare of non-human primates in research. Dr Daniel Adams speaks to the NC3Rs about how he drew on techniques from modern orthopaedics and dentistry to develop the refined recording chamber.

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Ow.ly - image uploaded by @NC3Rs (NC3Rs)

Ow.ly - image uploaded by @NC3Rs (NC3Rs) | Alternatives and refinements to animal research | Scoop.it
Book: The design & statistical analysis of animal experiments - an indispensable reference for all animal scientists http://t.co/d3yMOWtztp
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Global Market for in vitro and in silico Safety Testing Projected to Reach $9.9 Billion in 2017, According to BCC Research

Digital Journal is a digital media news network with thousands of Digital Journalists in 200 countries around the world. Join us!
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Mini-livers show promise to reduce animal use in science

Mini-livers show promise to reduce animal use in science | Alternatives and refinements to animal research | Scoop.it
International 3Rs Prize awarded for ground breaking liver research
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P&G develops first approved non-animal alternative for skin allergy testing

P&G develops first approved non-animal alternative for skin allergy testing | Alternatives and refinements to animal research | Scoop.it
Procter & Gamble scientists announce a milestone having developed the first non-animal alternative method for skin allergy testing approved by European authority.
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New technology can shorten animal testing time, lower costs: laboratory - Taipei Times

New technology can shorten animal testing time, lower costs: laboratory - Taipei Times | Alternatives and refinements to animal research | Scoop.it
The National Applied Research Laboratories yesterday said its National Laboratory Animal Center has begun using a new technology that can shorten the time needed for genetic animal testing experiments and also reduces the number of laboratory...
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3 January 2014 - Lab grown cells offer hope for new liver disease treatments - BBSRC

BBSRC funded scientists have shown that human liver cells produced from stem cells meet the current ‘gold standard’ for assessing drug toxicity, raising the possibility they could be used to develop new therapies for liver disease… (Lab grown cells...
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EU statistics show Decline in Animal Research Numbers | Speaking ...

EU statistics show Decline in Animal Research Numbers | Speaking ... | Alternatives and refinements to animal research | Scoop.it
Increasing work and funding into the 3Rs is also helping scientists find ways to reduce and replace (and refine) some animal research. The stats do provide a breakdown according to species (see pages 7-10).
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Human skin grown in laboratory

Human skin grown in laboratory | Alternatives and refinements to animal research | Scoop.it
Skin grown in the laboratory could replace animals in drug and cosmetics testing, according to UK scientists.
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Stem cells offer clue to bipolar disorder treatment - health - 25 March 2014 - New Scientist

Stem cells offer clue to bipolar disorder treatment - health - 25 March 2014 - New Scientist | Alternatives and refinements to animal research | Scoop.it
Brain cells grown from the skin cells of people with bipolar disorder are revealing details about how it arises
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From making bacteria glow to explaining science on the radio | NC3Rs blog

From making bacteria glow to explaining science on the radio | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it

Inaugural 3Rs prize winner, Siouxsie Wiles, reflects on her career progression over the eight years since receiving the prize and how the NC3Rs recognition has helped her to talk more openly about her research with animals.

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Liver Stand-In Could Replace Animal Testing : DNews

Liver Stand-In Could Replace Animal Testing : DNews | Alternatives and refinements to animal research | Scoop.it
A test tube version of a liver could one day eliminate drug testing on animals for human meds. Continue reading →
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Immune cells grown in lab could significantly reduce animal use in research

Immune cells grown in lab could significantly reduce animal use in research | Alternatives and refinements to animal research | Scoop.it

3Rs prize runner up Dr György Fejer, from Plymouth University, speaks to the NC3Rs about how his highly commended work with macrophage cells has the potential to reduce the number of mice used in infectious disease research

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Fewer laboratory animals needed for drug development thanks to fish scales

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Lab-grown human heart cells could mean fewer animals used in research - Bioengineer.org

Lab-grown human heart cells could mean fewer animals used in research - Bioengineer.org | Alternatives and refinements to animal research | Scoop.it
Scientists at Imperial College London are aiming to cut the need to use animals in research by improving methods for growing heart cells in the lab. Many new drugs fail to reach the market because of toxic effects on the heart. Research involving animals is currently integral to drug safety screening, but animal studies don’t...
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New tools – new implications for the 3Rs | NC3Rs blog

New tools – new implications for the 3Rs | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it

In the last week there have been two new technologies reported in Cell and Nature with potentially opposing implications for animal use and the 3Rs. Neuropharmacologist and NC3Rs Board member, Dr Ian Ragan explains...

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Going with the flow | NC3Rs blog

Going with the flow | NC3Rs blog | Alternatives and refinements to animal research | Scoop.it
National Centre for the 3Rs - Pioneering Better Science's insight:

Recent University of Edinburgh spin out, FibromEd Products Limited, and biotechnology company Kirkstall Limited, have been awarded funding from the NC3Rs CRACK IT Solutions programme. The award supports work to improve methods to detect potential drug toxicity in humans and aims to reduce the reliance on animal use in drug safety studies. Dr David Hay, FibromEd Products Limited, explains how. 

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Scientists develop alternative toxicity test for mascara

Scientists develop alternative toxicity test for mascara | Alternatives and refinements to animal research | Scoop.it
Researchers are developing an irritant test for mascara using the organism protozoa which could be used as an effective replacement for animal testing across the world.
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Science: High-tech drug research gives us a fuller picture - FT.com

Science: High-tech drug research gives us a fuller picture - FT.com | Alternatives and refinements to animal research | Scoop.it
From computer simulation to stem-cell cultivation, research into new drug treatments is being transformed by innovative technologies and an improved understanding of biology.
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Innovations with 3Rs benefits in The Scientist Top 10 | NC3Rs blog

National Centre for the 3Rs - Pioneering Better Science's insight:

This month The Scientist magazine announced the winners of their annual Top 10 Innovations 2013 competition, which highlights the best global technologies to enter the lab. Three of these have potential to replace, reduce or refine the use of animals in research and the NC3Rs’ Technology Programme Manager, Dr Anthony Holmes, gives his own verdict on each one.

more...
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