Traditional cell culture on plastic dishes or in flasks, rarely recapitulates the conditions cells experience in vivo. Over the past 20 years, many researchers looked for ways to culture cells in a more physiologically relevant manner. It is important to note that there is no silver bullet, each cell type needs a different environment and may need specific methods to study them. Content in this scoop aims to explain what real 3D culture really is and how it can be best applied to individual research needs.
White paper: Incorporating the Extracellular Matrix: New Opportunities in Cancer Research
Learn about the ECM proteins most relevant to cancer research. Self-organization models are described, with particular focus on the use of reconstituted basement membrane to study epithelial behavior. The broader application of ECM substrates is also explored in studying motility, in the context of adhesion, migration and invasion assays. Additional use of ECM products in vivo is discussed as a method to enhance the use of animal models.
An informative interactive guide (also available in downloadable pdf version)
which looks at different 3D cell culture technologies and it's application. Read the guide to learn which 3D cell culture format is best for you, which matrix or scaffold is most applicable to your needs and how to integrate your read-outs when implementing 3D cell culture.
3D Cell Culture in Drug Discovery presented by Dr. Erik Miljan
About Dr. Erik Miljan-
Dr Erik Miljan has over 10 years' experience in the stem cell biotech sector, from intellectual property (IP) portfolio management through product development to regulatory approval.
He initiated, implemented and delivered the operational and management strategy leading to the first ever stem cell-based product approved for clinical trial in the UK, in addition to delivering non-therapeutic stem cell products to market.
He has experience in international settings across both academia and industry in the US, Japan, Australia and the European Union
Dr.Erik Miljan talks the most important advances in the 3D technology and its contribution to conducting more realistic research.
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