21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)...
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Nanorobotic agents open the blood-brain barrier, offering hope for new brain treatments

Nanorobotic agents open the blood-brain barrier, offering hope for new brain treatments | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
(Nanowerk News) Magnetic nanoparticles can open the blood-brain barrier and deliver molecules directly to the brain, say researchers from the University of Montreal, Polytechnique Montréal, and CHU Sainte-Justine ("Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery"). This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain.


The research is important as currently 98% of therapeutic molecules are also unable to cross the blood-brain barrier.
“The barrier is temporary opened at a desired location for approximately 2 hours by a small elevation of the temperature generated by the nanoparticles when exposed to a radio-frequency field,” explained first author and co-inventor Seyed Nasrollah Tabatabaei. “Our tests revealed that this technique is not associated with any inflammation of the brain.


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(Nanowerk News) Magnetic nanoparticles can open the blood-brain barrier and deliver molecules directly to the brain, say researchers from the University of Montreal, Polytechnique Montréal, and CHU Sainte-Justine ("Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery"). This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain.


The research is important as currently 98% of therapeutic molecules are also unable to cross the blood-brain barrier.
“The barrier is temporary opened at a desired location for approximately 2 hours by a small elevation of the temperature generated by the nanoparticles when exposed to a radio-frequency field,” explained first author and co-inventor Seyed Nasrollah Tabatabaei. “Our tests revealed that this technique is not associated with any inflammation of the brain.


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http://www.scoop.it/t/21st-century-innovative-technologies-and-developments/?tag=Nano


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Krishan Maggon 's curator insight, March 26, 2015 12:33 AM

Image   Wellcome Image Awards 2015

 

Delivering drugs into the brain

Geoff Ahloy-Martin's curator insight, March 27, 2015 4:54 AM

Nanotechnology shows that we are able to be much more precise with our health and robotics applications. While previous iterations of this technology would result in problematic side-effects, the risk could be reduced or even entirely eliminated with this newer technology

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Des nanoparticules pour refermer les plaies

Des nanoparticules pour refermer les plaies | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Des chercheurs français de l'ESPCI-ParisTech viennent de démontrer l’efficacité de nanoparticules pour réparer des tissus et même des organes mous comme le foie, pour lequel aucune méthode...


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Louis Joseph's comment, May 12, 2014 12:44 PM
C'est interessant ! Il ne faut pas oublier par exemple les effets bénéfiques des nonoparticules d'argent qui entre autre remplacent plus de 600 médicaments et remèdes. Comme par hasard: on n'en parle plus (lobbies pharmaceutiques)...
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Nanotechnology researchers produce new anti-cancer drug from turmeric

Nanotechnology researchers produce new anti-cancer drug from turmeric | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Nanotechnology researchers produce new anti-cancer drug from turmeric


The compound is made of curcumin found in the extract of turmeric, and has desirable physical and chemical stability and prevents the proliferation of cancer cells.In this drug, curcumin with high efficiency (approximately 87%) was loaded in the polymeric nanocarrier, and it created a spherical structure with the size of 140 nm.

The drug has high physical and chemical stability. The drug was used successfully in laboratory conditions in the treatment of a type of aggressive tumor in the central nervous system, called glioblastoma (GBM).


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Tiny transistors for extreme environs

Tiny transistors for extreme environs | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Tiny transistors for extreme environs
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Electronic nose with artificial sensing intelligence

Electronic nose with artificial sensing intelligence | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Nanowire field-effect sensors show significant advantages of real-time, label-free and highly sensitive detection of a wide range of analytes in liquid phase, including proteins, nucleic acids, small molecules, and viruses in single-element or multiplexed formats. Motivated by the unique features of these sensors and the ease to integrate them in the currently available VLSI technology, researchers used molecularly modified silicon nanowire FETs to detect volatile organic compounds (VOCs) that are associated with environmental pollution, quality control, explosive materials, or various diseases.
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Nanotech researchers prove two-step method for potential pancreatic cancer treatment

Nanotech researchers prove two-step method for potential pancreatic cancer treatment | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
A new method of microscopic drug delivery that could greatly improve the treatment of deadly pancreatic cancer has been proven to work in mice at UCLA's Jonsson Comprehensive Cancer Center.
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Nanoparticle vaccine offers better protection - MIT News Office

Nanoparticle vaccine offers better protection - MIT News Office | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Particles that deliver vaccines directly to mucosal surfaces could defend against many infectious diseases.
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Brain-penetrating nanoparticle attacks deadly tumors

Brain-penetrating nanoparticle attacks deadly tumors | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
Brain-penetrating nanoparticle attacks deadly tumors

 

(Nanowerk News) Scientists have developed a new approach for treating a deadly brain cancer that strikes 15,000 in the United States annually and for which there is no effective long-term therapy. The researchers, from Yale and Johns Hopkins, have shown that the approach extends the lives of laboratory animals and are preparing to seek government approval for a human clinical trial.

 

“We wanted to make a system that would penetrate into the brain and deliver drugs to a greater volume of tissue,” said Mark Saltzman, a biomedical engineer at Yale and principal investigator of the research. “Drugs have to get to tumor cells in order to work, and they have to be the right drugs.


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'Glowing' new nanotechnology guides cancer surgery, also kills remaining malignant cells

'Glowing' new nanotechnology guides cancer surgery, also kills remaining malignant cells | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it

A new system developed at Oregon State University to improve cancer surgery uses a nanoparticle called a dendrimer to carry a drug into cancer cells, that can set the stage for improved surgery and also phototherapy. (Graphic courtesy of Oregon State University)


Technology such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors, as well as using near-infrared light therapies that can kill remaining cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.

Read more: 'Glowing' new nanotechnology guides cancer surgery, also kills remaining malignant cells 


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A new system developed at Oregon State University to improve cancer surgery uses a nanoparticle called a dendrimer to carry a drug into cancer cells, that can set the stage for improved surgery and also phototherapy. (Graphic courtesy of Oregon State University)


Technology such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors, as well as using near-infrared light therapies that can kill remaining cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.

Read more: 'Glowing' new nanotechnology guides cancer surgery, also kills remaining malignant cells 


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http://www.scoop.it/t/21st-century-innovative-technologies-and-developments/?tag=Nano


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Marcela Bravo's curator insight, January 13, 2015 7:15 AM

añada su visión ...

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New nanotechnology method sneaks drugs into cancer cells before triggering release

New nanotechnology method sneaks drugs into cancer cells before triggering release | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it
New nanotechnology method sneaks drugs into cancer cells before triggering release


Biomedical engineering researchers have developed a nanotechnology anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release ("Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery"). The method can be likened to keeping a cancer-killing bomb and its detonator separate until they are inside a cancer cell, where they then combine to destroy the cell.


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Biomedical engineering researchers have developed a nanotechnology anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release ("Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery"). The method can be likened to keeping a cancer-killing bomb and its detonator separate until they are inside a cancer cell, where they then combine to destroy the cell.


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Nanofiber bandages could safely seal your next wound

Nanofiber bandages could safely seal your next wound | 21st Century Innovative Technologies and Developments as also discoveries, curiosity ( insolite)... | Scoop.it

Over-the-counter liquid bandages are great for sealing up minor cuts and scrapes, but sutures are still required to close most surgical incisions and deeper wounds. A group of scientists at the...

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